Improved aqueous solubility,bioaccessibility and cellular uptake of quercetin following pH-driven encapsulation in whey protein isolate

The purpose of this study was to increase the water solubility and potential bioavailability of quercetin by encapsulation in whey protein isolate (WPI) based on a green, efficient pH-driven method. According to the results, the water solubility of quercetin increased by 346.9: times after loading into WPI nanoparticles. When the initial quercetin concentration was 0.25 mg mL⁻¹ and WPI was 2% w/v, the encapsulation efficiency reached 94.1%, the Z-average diameter was 36.63 nm, and the zeta potential was −36.4 mV at pH 7.0. The fluorescence spectroscopy assay suggested the molecular complexation of quercetin and WPI at pH 12.0. X-ray diffraction assay indicated the enclosure of amorphous quercetin in WPI. Correspondingly, the bioaccessibility increased from 2.76% to 31.23% and the Caco-2 cell monolayer uptake increased from 0% to 2.12% after nanoencapsulation. This work confirmed that the pH-driven method is an effective approach to prepare WPI–quercetin nanocapsules to improve physical and potentially biological properties of quercetin.     

超高效液相色谱串联质谱法测定烟草中的噁霉灵残留

为降低烟草中噁霉灵检测中的基质干扰，提高检测灵敏度和和稳定性，通过试验建立了以QuEChERS为样品前处理方法、液相色谱串联质谱仪为检测仪器的烟草中噁霉灵残留检测方法。样品加水浸润后，经丙酮提取、盐析试剂包除水、石墨化炭黑除杂后，采用Agilent ZORBAX 300SB-C8液相色谱柱（2.1 mm×100 mm，1.8 μm）分离，甲醇-水程序洗脱，ESI雾化，串联质谱MRM检测。结果发现，该方法在0.0025~0.0500 mg/L范围内线性良好，决定系数r²=0.9996，定量检测限1.06 μg/L，回收率在90.8%~92.0%之间，相对标准偏差为5.1%。运用该方法测定烟草中的噁霉灵，操作简单，检测精度高，满足CORESTA对烟草农残检测的要求。     

以EMD作基础的氧化锰制成湿度敏感器的新技术

最近国外报道把ＥＭＤ粉末等制成湿度敏感器的技术，但对其作用机理的解释尚有欠妥之处，本文除简介此类湿度敏感器的工艺之外，还利用我们研究水蒸气对ＥＭＤｏＡ附的理论予以阐释，并确认其合理与否     

等温脉冲自由射流压力场动态特性的实验研究

针对冶金工业过程脉冲燃烧及脉冲流技术所进行研究的基础部分,借助于计算机辅助信号分析手段,运用湍流统计理论,对等温脉冲自由射流压力场动态特性进行了系统的实验研究。实验的Re范围为19486～93936,st范围为0～0.057,所对应的射流脉冲频率为0～25Hz。研究结果表明;脉冲射流极大地提高了射流区压力波动水平,任何受气体的动量、热量和质量传递制约的工业过程均可望通过适当地采用脉冲流技术加以强化.     

iMapReduce: A Distributed Computing Framework for Iterative Computation

Iterative computation is pervasive in many applications such as data mining, web ranking, graph analysis, online social network analysis, and so on. These iterative applications typically involve massive data sets containing millions or billions of data records. This poses demand of distributed computing frameworks for processing massive data sets on a cluster of machines. MapReduce is an example of such a framework. However, MapReduce lacks built-in support for iterative process that requires to parse data sets iteratively. Besides specifying MapReduce jobs, users have to write a driver program that submits a series of jobs and performs convergence testing at the client. This paper presents iMapReduce, a distributed framework that supports iterative processing. iMapReduce allows users to specify the iterative computation with the separated map and reduce functions, and provides the support of automatic iterative processing within a single job. More importantly, iMapReduce significantly improves the performance of iterative implementations by (1) reducing the overhead of creating new MapReduce jobs repeatedly, (2) eliminating the shuffling of static data, and (3) allowing asynchronous execution of map tasks. We implement an iMapReduce prototype based on Apache Hadoop, and show that iMapReduce can achieve up to 5 times speedup over Hadoop for implementing iterative algorithms.     

高温高压设备瞬态密封分析的三维力学与传热学模型

以大型加氢反应器的高压法兰密封结构为研究对象，建立了瞬态及稳态密封分析的三维力学与传热学模型，主要解决了螺栓载荷的动态模拟和螺栓孔内空气环层的传热计算问题。利用该模型对加氢反应器的瞬态及稳态密封状况进行了计算。     

有限元方法在离心机转鼓强度分析中的应用

在回顾以往转鼓强度分析的基础上 ,指出了目前转鼓有限元应力分析所存在的问题 ,给出了提高计算精度和保证模拟有效性的注意事项 ,并探讨了转鼓强度评定准则     

在矿浆过滤预处理中表面活性剂的应用

针对钼矿的基本物性,筛选合适的表面活性剂,进行钼矿浆过滤条件的试验研究。结果表明,钼矿浆中加入合适的表面活性剂后,增加了滤饼厚度,降低了滤饼湿含量,提高了对矿浆的处理能力。     

基于隐私保护的可证明安全委托计算协议

通过云计算提供的委托计算服务能够为委托方节省大量的计算时间和计算成本,但如何保证委托计算的隐私性和可证明安全性是具有挑战性的问题。结合全同态加密和多线性映射技术的优势,提出基于隐私保护的可证明安全多元多项式委托计算协议。根据委托计算的输入输出隐私安全需求设计委托计算安全模型,通过多线性映射方案和全同态加密技术构造任意第三方可公开验证的委托计算协议,并在标准模型下基于多线性Diffie-Hellman困难性问题假设证明协议的安全性与隐私性。实验与性能分析结果表明,该协议可保证安全性,同时能够减少计算成本,满足大数据环境下委托计算模式的应用需求。     

太阳能电池自动封装系统的研究

为了保证太阳能电池在恶劣的太空环境下能可靠运行，在太阳能电池布贴前，必须进行抗辐照玻璃盖片的封装操作，以达到保护太阳能电池的目的。抗辐照特性是空间太阳能电池区别于地面应用的太阳能电池的重要特征之一。抗辐照玻璃盖片的封装操作是空间太阳能电池方阵制造过程的重要环节。本文通过机器人技术与滴胶技术的结合，设计出一套太阳能电池自动封装系统，实现太阳能电池片的高精度定量喷涂和抗辐照玻璃盖片的非真空环境下的精确封装。文章详细介绍了设计要求、设计思想、系统组成、工作原理和实现过程，并分析了系统的技术特点。