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1.
Effect of the Twisting Motion on the Nonunifornities of Transmyocardial Fiber Mechanics and Energy Demand A Theoretical Study 总被引:3,自引:0,他引:3
The contraction of the left ventricle (LV) is manifested by a distribution of strains and strain rates throughout the muscle thickness. Using a nested shell spheroidal model of the LV, which accounts for a fiber angle distribution from + 60°at the endocardium to ?60° at the epicardium, and the radial electrical activation pattern from the endocardium to the epicardium, it can be shown that endocardial layers undergo higher strains than the epicardial layers throughout the cardiac cycle, and higher length changes characterize the endocardial sarcomeres relative to the epicardial sarcomeres. However, the calculated nonuniformities in the sarcomeres' shortening are significantly moderated when the physiological twisting motion of the LV around the longitudinal axis is accounted for. Thus, the twisting motion of the heart is a basic mechanism by which the sarcomere function is maintained within its physiological range. 相似文献
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Symbolic parametrization of curves 总被引:1,自引:0,他引:1
If algebraic varieties like curves or surfaces are to be manipulated by computers, it is essential to be able to represent these geometric objects in an appropriate way. For some applications an implicit representation by algebraic equations is desirable, whereas for others an explicit or parametric representation is more suitable. Therefore, transformation algorithms from one representation to the other are of utmost importance.We investigate the transformation of an implicit representation of a plane algebraic curve into a parametric representation. Various methods for computing a rational parametrization, if one exists, are described. As a new idea we introduce the concept of working with classes of conjugate (singular or simple) points on curves. All the necessary operations, like determining the multiplicity and the character of the singular points or passing a linear system of curves through these points, can be applied to such classes of conjugate points. Using this idea one can parametrize a curve if one knows only one simple point on it. We do not propose any new method for finding such a simple point. By classical methods a rational point on a rational curve can be computed, if such a point exists. Otherwise, one can express the coordinates of such a point in an algebraic extension of degree 2 over the ground field. 相似文献
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Javier Lara-Romero Rafael Maya-Yescas José Luis Rico-Cerda José Luis Rivera-Rojas Fernando Chiñas Castillo Matey Kaltchev 《Thin solid films》2006,496(2):463-468
The thermal decomposition of model extreme-pressure lubricant additives on clean iron was studied in ultrahigh vacuum conditions using molecular beam strategies. Methylene chloride and chloroform react to deposit a solid film consisting of FeCl2 and carbon, and evolve only hydrogen into the gas phase. No gas-phase products and less carbon on the surface are detected in the case of carbon tetrachloride. Dimethyl and diethyl disulfide react on clean iron to deposit a saturated sulfur plus carbon layer at low temperatures (∼600 K) and an iron sulfide film onto a Fe + C underlayer at higher temperatures (∼950 K). Methane is the only gas-phase product when dimethyl disulfide reacts with iron. Ethylene and hydrogen are detected when diethyl disulfide is used. 相似文献
6.
On formalism and stability of switched systems 总被引:1,自引:1,他引:0
In this paper,we formulate a uniform mathematical framework for studying switched systems with piecewise linear partitioned state space and state dependent switching.Based on known results from the the... 相似文献
7.
A fuzzy queue-aware routing approach for wireless mesh networks 总被引:1,自引:0,他引:1
Billy Pinheiro Vagner Nascimento Rafael Lopes Eduardo Cerqueira Antonio Abelem 《Multimedia Tools and Applications》2012,61(3):747-768
Recent advances in Wireless Mesh Networks (WMNs) have overcome the drawbacks of traditional wired and ad-hoc networks and now they are seen as a means of allowing last mile communications with quality level assurance in Future Multimedia Systems. However, new routing schemes are needed to provide end-to-end Quality of Service (QoS) and Quality of Experience (QoE) support for delay/loss/jitter-sensitive multimedia applications. The well-known OLSR (Optimized Link State Routing) protocol with ETX (Expected Transmission Count) metric brings many benefits to the path selection process, but has a drawback with regard to queue availability management, which reduces the system performance. This problem is caused when OLSR-EXT control messages are exchanged and the queues of mesh routers along the end-to-end communication path are overloaded. As a result, multimedia-related packets will suffer from loss/delay/jitter and the overall system performance will decrease. This paper proposes the Optimized Link State Routing-Fuzzy ETX Queue (OLSR-FEQ) protocol to overcome the limitations of OLSR-ETX regarding queue availability, QoS and QoE assurance. OLSR-FEQ optimizes network and user-based parameters by coordinating queue availability, QoS and fuzzy issues in the routing decision process as a way of allocating the best paths for multimedia applications. Performance evaluations were carried out with the Network Simulator (NS-2.34) to show the benefits of the proposed solution when compared with existing routing schemes, namely OLSR-ETX, OLSR-FLC, OLSR-MD and HWMP (IEEE 802.11s standard), regarding QoS (unsuccessful packet delivery and throughput) and QoE (PSNR, SSIM, VQM and MOS) parameters. 相似文献
8.
Ignacio Hernandez Laura Tesoro Rafael Ramirez-Carracedo Javier Diez-Mata Sandra Sanchez Marta Saura Jose Luis Zamorano Carlos Zaragoza Laura Botana 《International journal of molecular sciences》2021,22(6)
In response to cardiac ischemia/reperfusion, proteolysis mediated by extracellular matrix metalloproteinase inducer (EMMPRIN) and its secreted ligand cyclophilin-A (CyPA) significantly contributes to cardiac injury and necrosis. Here, we aimed to investigate if, in addition to the effect on the funny current (I(f)), Ivabradine may also play a role against cardiac necrosis by reducing EMMPRIN/CyPA-mediated cardiac inflammation. In a porcine model of cardiac ischemia/reperfusion (IR), we found that administration of 0.3 mg/kg Ivabradine significantly improved cardiac function and reduced cardiac necrosis by day 7 after IR, detecting a significant increase in cardiac CyPA in the necrotic compared to the risk areas, which was inversely correlated with the levels of circulating CyPA detected in plasma samples from the same subjects. In testing whether Ivabradine may regulate the levels of CyPA, no changes in tissue CyPA were found in healthy pigs treated with 0.3 mg/kg Ivabradine, but interestingly, when analyzing the complex EMMPRIN/CyPA, rather high glycosylated EMMPRIN, which is required for EMMPRIN-mediated matrix metalloproteinase (MMP) activation and increased CyPA bonding to low-glycosylated forms of EMMPRIN were detected by day 7 after IR in pigs treated with Ivabradine. To study the mechanism by which Ivabradine may prevent secretion of CyPA, we first found that Ivabradine was time-dependent in inhibiting co-localization of CyPA with the granule exocytosis marker vesicle-associated membrane protein 1 (VAMP1). However, Ivabradine had no effect on mRNA expression nor in the proteasome and lysosome degradation of CyPA. In conclusion, our results point toward CyPA, its ligand EMMPRIN, and the complex CyPA/EMMPRIN as important targets of Ivabradine in cardiac protection against IR. 相似文献
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Rafael S. Pinto João P. Serra João C. Barbosa Renato Gonçalves Maria M. Silva Senentxu Lanceros-Méndez Carlos M. Costa 《大分子材料与工程》2021,306(11):2100372
Considering the high levels of materials used in the fields of electronics and energy storage systems, it is increasingly necessary to take into consideration environmental impact. Thus, it is important to develop devices based on environmentally friendlier materials and/or processes, such as additive manufacturing techniques. In this work, poly(vinylidene fluoride) (PVDF) and poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP) are prepared by direct-ink-writing (DIW) by varying solvent evaporation temperature and fill density percentage. Different morphologies for both polymers are obtained, including dense films and porous membranes, as well as different electroactive β-phase content, thermal and mechanical properties. The dielectric constant and piezoelectric d33 coefficient for dense films reaches up to 16 at 1 kHz and 4 pC N−1, respectively for PVDF-HFP with a fill density of 80 and a solvent evaporation temperature of 50 °C. Porous structures are developed for battery separator membranes in lithium-ion batteries, with a highest ionic conductivity value of 3.8 mS cm−1 for the PVDF-HFP sample prepared with a fill density of 100 and a solvent evaporation temperature of 25 °C, the sample showing an excellent cycling performance. It is demonstrated that electroactive films and membranes can be prepared by direct-ink writing suitable for sensors/actuators and energy storage systems. 相似文献