Expression of a functional tagged human thyrotropin receptor in HeLa cells using recombinant vaccinia virus

The aim of the present study was to assess the prognostic relevance of relatives' interactive behaviour towards the patient, as covered by the Münster Family Interview (MFI), to the further course of the schizophrenic illness. The MFI is a family interview (of the whole family, including the patient) designed to record the emotional family atmosphere based on the concept of expressed emotion (EE). The ratings take place directly after the interview on five scales (criticism, hostility, overinvolvement, resignation and warmth), the resignation scale being added to the 'classic' EE scales. Ninety-nine families of outpatients diagnosed with schizophrenia according to the DSM-III were examined with the MFI during a home visit. The patients were seen 1 and 2 years after the first examination. The target criteria selected for the prognostic significance of the interaction measurements were: rehospitalisation within 2 years; extent of symptoms after 1 year, and psychosocial skills after 1 year. The significance of the interaction dimensions was verified in regression models. The control variable used in the regression models was the Strauss-Carpenter scale. Regression models were produced for the total group and for a subgroup of moderately ill patients. All target criteria yielded serviceable prediction models. The most important variable for prediction was the control variable, the Strauss-Carpenter scale. However the interaction variables made additional contributions to the prognosis, especially in the subgroup of moderately ill patients. The best MFI scale for all the outcome criteria was resignation; criticism predicted only the symptomatology, and emotional overinvolvement the level of social functioning after 1 year. In conclusion, practical work with families of schizophrenic patients should emphasise the protective function of relatives towards patients more strongly.     

Relating the Morphology of Poly(p‐phenylene vinylene)/Methanofullerene Blends to Solar‐Cell Performance

The performance of bulk‐heterojunction solar cells based on a phase‐separated mixture of donor and acceptor materials is known to be critically dependent on the morphology of the active layer. Here we use a combination of techniques to resolve the morphology of spin cast films of poly(p‐phenylene vinylene)/methanofullerene blends in three dimensions on a nanometer scale and relate the results to the performance of the corresponding solar cells. Atomic force microscopy (AFM), transmission electron microscopy (TEM), and depth profiling using dynamic time‐of‐flight secondary ion mass spectrometry (TOF‐SIMS) clearly show that for the two materials used in this study, 1‐(3‐methoxycarbonyl)propyl‐1‐phenyl‐[6,6]‐methanofullerene (PCBM) and poly[2‐methoxy‐5‐(3′,7′‐dimethyloctyloxy)‐1,4‐phenylene vinylene] (MDMO‐PPV), phase separation is not observed up to 50 wt.‐% PCBM. Nanoscale phase separation throughout the film sets in for concentrations of more than 67 wt.‐% PCBM, to give domains of rather pure PCBM in a homogenous matrix of 50:50 wt.‐% MDMO‐PPV/PCBM. Electrical characterization, under illumination and in the dark, of the corresponding photovoltaic devices revealed a strong increase of power conversion efficiency when the phase‐separated network develops, with a sharp increase of the photocurrent and fill factor between 50 and 67 wt.‐% PCBM. As the phase separation sets in, enhanced electron transport and a reduction of bimolecular charge recombination provide the conditions for improved performance. The results are interpreted in terms of a model that proposes a hierarchical build up of two cooperative interpenetrating networks at different length scales.     

聚乙烯与聚丙烯单组分复合材料研究进展

综述了聚乙烯、聚丙烯单组分复合材料的发展概况及最新研究动态。介绍了熔融膜压法、粉末浸渍法、溶液浸渍法三类制备聚乙烯单组分复合材料的传统方法。重点介绍了热压法、共挤出热压法两类制备单组分复合材料的创新方法。分析了各制备方法的优缺点:熔融法、粉末法与溶液法效率均较低且复合材料中纤维含量较少,力学性能不佳;热压法由于初始材料为100％纤维,从而综合效率较高,力学性能良好,缺点为加工温度过于苛刻;共挤出热压法效率较高,在具有高的增强相含量的同时拥有较宽的加工温度范围,缺点为增强相强度需进一步提高。最后介绍了单组分复合材料的应用并对其研究与应用前景作了展望。     

Geschäftsmodelle

The business model concept, although a relatively new topic for research, has garnered growing attention over the past decade. Whilst it has been robustly defined, the concept has so far attracted very little substantive research. In the context of the wide-spread digitization of businesses and society at large, the logic inherent in a business model has become critical for business success and, hence, a focus for academic inquiry. The business model concept is identified as the missing link between business strategy, processes, and Information Technology (IT). The authors argue that the BISE community offers distinct and unique competencies (e.g., translating business strategies into IT systems, managing business and IT processes, etc.) that can be harnessed for significant research contributions to this field. Within this research gap three distinct streams are delineated, namely, business models in IT industries, IT enabled or digital business models, and IT support for developing and managing business models. For these streams, the current state of the art, suggest critical research questions, and suitable research methodologies are outlined.     

Correction to: How to model and prove hybrid systems with KeYmaera: a tutorial on safety

International Journal on Software Tools for Technology Transfer -     

User experimentation: an evaluation of velocity control techniques in immersive virtual environments

While many of the existing velocity control techniques are well designed, the techniques are often application-specific, making it difficult to compare their effectiveness. In this paper, we evaluate five known velocity control techniques using the same experimental settings. We compare the techniques based on the assumption that a good travel technique should be easy to learn and easy to use, should cause the user to have few collisions with the VE, should allow the user to complete tasks faster, and should promote better recollection of the environment afterwards. In our experiments, we ask twenty users to use each velocity control technique to navigate through virtual corridors while performing information-gathering tasks. In all cases, the users use pointing to indicate the direction of travel. We then measure the users’ ability to recollect the information they see in the VE, as well as how much time they spend in the VE and how often they collide with the virtual walls. After each test, we use questionnaires to evaluate the ease of learning and ease of use of the velocity control technique, and the users’ sense of presence in the environment. Each of the travel techniques is then evaluated based on the users’ performances in the VE and the results of their questionnaires.     

A 3D face matching framework for facial curves

Among the many 3D face matching techniques that have been developed, are variants of 3D facial curve matching, which reduce the amount of face data to one or a few 3D curves. The face’s central profile, for instance, proved to work well. However, the selection of the optimal set of 3D curves and the best way to match them has not been researched systematically. We propose a 3D face matching framework that allows profile and contour based face matching. Using this framework we evaluate profile and contour types including those described in the literature, and select subsets of facial curves for effective and efficient face matching. With a set of eight geodesic contours we achieve a mean average precision (MAP) of 0.70 and 92.5% recognition rate (RR) on the 3D face retrieval track of the Shape Retrieval Contest (SHREC’08), and a MAP of 0.96 and 97.6% RR on the University of Notre Dame (UND) test set. Face matching with these curves is time-efficient and performs better than other sets of facial curves and depth map comparison.     

Validation of interferometric imaging from a pupil-masking experiment on a solar telescope

We present the results of a pupil-masking experiment that uses the Sun as the source object. The goal of our experiment was a proof-of-concept validation for a Fizeau (image-plane) interferometric beam combination with a complex source that overfilled the field of view. We employed a phase-diversity technique to measure the optical phases required to recover the instantaneous optical transfer function for the masked pupil. We used a Wiener filter to deconvolve the dirty images.