Chromophore-Free Sealing and Repair of Soft Tissues Using Mid-Infrared Light-Activated Biosealants

Poor strength, infection, leakage, long procedure times, and inflammation limit the efficacy of common tissue sealing devices in surgeries and trauma. Light-activated sealing is attractive for tissue sealing and repair, and can be facilitated by the generation of local heat following absorption of nonionizing laser energy by chromophores. Here, the inherent ability of biomaterials is exploited to absorb nonionizing, mid-infrared (midIR) light in order to engender rapid photothermal sealing and repair of soft tissue wounds. In this approach, the biomaterial simultaneously acts as a photothermal convertor as well as a biosealant, which dispenses the need for exogeneous light-absorbing nanoparticles or dyes. Biomechanical recovery, mathematical modeling, histopathology analyses, tissue strain mapping using digital imaging correlation, and visualization of the biosealant-tissue interface using hyperspectral imaging indicate superior performance of midIR sealing in live mice compared to conventional sutures and glue. The midIR-biosealant approach demonstrates rapid sealing of soft tissues, improves cosmesis, lowers potential for scarring, obviates safety concerns because of the nonionizing light used, and allows adoption of a wide diversity of biomaterials. Taken together, the studies demonstrate a novel advance both in biomaterials for surgical sealing along with the use of nonionizing midIR light, with high potential for clinical translation.     

An epidemic of roller-blade injuries in children

Roller blading is a new and increasingly popular leisure activity in many countries. We reviewed 110 consecutive patients with roller-blade injuries between 1 January and 30 June 1996. The patients ranged from 4 to 14 years in age (mean 6.5 years). Eighty-three (75.4%) sustained injuries to the upper limb and 27 (24.5%) injured the lower limb. Fifty-six patients, were girls and 54 were boys. Of the 110 patients, 79 (72.7%) sustained fractures, 28 (25.4%) soft tissue injuries and 3 (2.7%) dislocations. Eighty-three (75.4%) of the patients wore no protective equipment on the limbs. Four months following injury 103 (93.6%) patients were fully recovered. The mean duration of school absence was 3 days. Subsequently 101 children returned to using roller-blades following injury. Seventy-three (66.3%) of these now use protective equipment. We found that injuries were unrelated to age or duration of roller-blading experience or to the brand-name of roller blades used, and that most of our patients wore no protective equipment at the time of injury.     

A spatio‐temporal water quality assessment of the Beas and Sutlej Rivers at the Harike Wetland: A Ramsar site in Punjab,India

Lakes play a vital role in regulating water storage, flow of river water, and ultimately maintaining a balanced ecosystem. Spatial and temporal variations in physicochemical parameters of water in Harike Wetland, a Ramsar site in the northwestern state of Punjab, India, were studied. This study was conducted on a monthly basis from January to December 2015. The water quality was studied at ten locations from sites 1 to 10 upstream, central and downstream from Harike Lake for ten physicochemical parameters, including temperature, pH, electrical conductivity, turbidity, dissolved oxygen concentration biological oxygen demand, nitrate and phosphate concentrations and salinity. The findings of this study revealed that, except for temperature and pH, all parameters exhibited relatively higher values for the Sutlej River, compared with the Beas River, with sampling sites 5 to site 7 exhibiting intermediate results. The mean seasonal temperature variations ranged from 16.9 to 26.6 °C, the pH from 7.7 to 8.2, electrical conductivity from 223 to 303 μS cm^?1 and TDS concentration from 148.7 to 180.4 ppm. Correlation analysis was conducted to assess the relations between the variables. The electrical conductivity exhibited a high positive correlation with salinity and biological oxygen demand, whereas it correlated negatively with the dissolved oxygen concentration. Box and whisker plots were also plotted for the study results to better examine the data distribution.     

Geospatial technology applied to spatiotemporal assessment of Harike Wetland,Punjab

The Harike Wetland situated in Punjab is a Ramsar site and a wetland of national importance. The present study was undertaken to assess the spatiotemporal dynamics of the wetland on the basis of geospatial technology and ground‐based studies. Landsat images for the years 2002 and 2014 were acquired from the United States Geological Survey and classified digitally to generate landuse/land cover maps involving four classes (water, grassland (including water hyacinth), agriculture, built‐up (settlement), barren land). The total area of the Harike Wetland was found to be 8023.68 ha. Water sampling at eleven sites was carried out and evaluated for physicochemical parameters. The water quality at several sampling points was found to be severely degraded. Change detection analysis revealed the submerged area (area under water) and grassland (including water hyacinth) had decreased over the past 12 years, whereas that area under agriculture and built‐up land has increased, indicating a shrinkage in the total wetland area. The present study also indicated that the near‐infrared band is a good indicator of water quality parameters, as indicated by the significant positive correlation between the near‐infrared band and relevant water parameters. Because the wetland is important from both an ecological perspective and economic perspective, regular monitoring is recommended, for which geospatial technology has proven to be very useful.     

A statistical framework for few-shot action recognition

Along with the exponential growth of online video creation platforms such as Tik Tok and Instagram, state of the art research involving quick and effective action/gesture recognition remains crucial. This work addresses the challenge of classifying short video clips, using a domain-specific feature design approach, capable of performing significantly well using as little as one training example per action. The method is based on Gunner Farneback’s dense optical flow (GF-OF) estimation strategy, Gaussian mixture models, and information divergence. We first aim to obtain accurate representations of the human movements/actions by clustering the results given by GF-OF using K-means method of vector quantization. We then proceed by representing the result of one instance of each action by a Gaussian mixture model. Furthermore, using Kullback-Leibler divergence (KL-divergence), we attempt to find similarities between the trained actions and the ones in the test videos. Classification is done by matching each test video to the trained action with the highest similarity (a.k.a lowest KL-divergence). We have performed experiments on the KTH and Weizmann Human Action datasets using One-Shot and K-Shot learning approaches, and the results reveal the discriminative nature of our proposed methodology in comparison with state-of-the-art techniques.

     

Supervised Multi‐Rejector of Periodic Disturbances for Nonlinear Systems Using Decoupled State Multimodel

In this paper, a multi‐rejector of periodic disturbances is proposed for discrete‐time nonlinear systems represented by a decoupled state multimodel. We report a decoupled state multimodel repetitive‐predictive control based on a supervised algorithm to ensure reference trajectory tracking and periodic disturbances rejection. Partial predictors associated to the local controllers make the best choice of the most valid partial controller that meets the desired closed loop performances. The effectiveness of the supervised multi‐rejector is shown via a simulation example. The obtained results are satisfactory and show a good rejection of periodic disturbances and reference trajectory tracking.     

Efficient hardware architecture of 2D-scan-based wavelet watermarking for image and video

This paper describes an efficient hardware architecture of 2D-Scan-based-Wavelet watermarking for image and video. The potential application for this architecture includes broadcast monitoring of video sequences for High Definition Television (HDTV) and DVD protection and access control. The proposed 2D design allows even distribution of the processing load onto a set of filters, with each set performing the calculation for one dimension according to the scan-based process. The video protection is achieved by the insertion of watermarks bank within the middle frequency of wavelet coefficients related to video frames by their selective quantization. The 2-D DWT is applied for both video stream and watermark in order to make the watermarking scheme robust and perceptually invisible. The proposed architecture has a very simple control part, since the data are operated in a row-column-slice fashion. This organization reduces the requirement of on-chip memory. In addition, the control unit selects which coefficient to pass to the low-pass and high-pass filters. The on-chip memory will be small as compared to the input size since it depends solely on the filter sizes. Due to the pipelining, all filters are utilized for 100% of the time except during the start-up and wind-down times. The major contribution of this research is towards the selection of appropriate real time watermarking scheme and performing a trade-off between the algorithmic aspects of our proposed watermarking scheme and the hardware implementation technique. The hardware architecture is designed, as a watermarking based IP core with the Avalon interface related to NIOS embedded processor, and tested in order to evaluate the performance of our proposed watermarking algorithm. This architecture has been implemented on the Altera Stratix-II Field Programmable Gate Array (FPGA) prototyping board. Experimental results are presented to demonstrate the capability of the proposed watermarking system for real time applications and its robustness against malicious attacks.     

Hybrid micro electrostatic actuator

A hybrid micro-electrostatic actuator is presented. The actuator integrates a vertical comb driving (VCD) unit and a parallel-plate driving (PPD) unit. The hybrid actuator is fabricated using a one structural layer microfabrication process, i.e., MetalMUMPs instead of a two-layer microfabrication process needed for traditional vertical comb-drive actuators by taking advantage of the residual stress gradient in the MetalMUMPs nickel layer, which raises the moving parts of the actuator above the substrate after release. The hybrid actuator significantly simplifies the fabrication process for vertical comb-drive actuators, i.e., turning a process requiring two structural layers into a process requiring only one structural layer and thus avoids any misalignment between the two layers. The hybrid actuator can generate larger force and then a larger displacement than the actuator having only the VCD with the same area since no extra space is needed for the PPD unit which uses the moving electrode existing in the VCD unit and a fixed electrode under the VCD unit. The VCD and PPD units in the hybrid actuator are subject to the same driving voltage and work together to pull the moving parts of the actuator downward. A model is established for the hybrid actuator to analyze its displacement. The analytical results show that displacement of the moving part of the hybrid actuator is about half of the gap between the electrodes of the PPD unit. Prototypes are fabricated and tested. With a driving voltage of 150 V, the hybrid actuator achieved a measured displacement of 6.48 µm.     

Fault and attack management in all-optical networks

Network management for optical networks faces additional security challenges that arise by using transparent optical network components in communication systems. While some available management mechanisms are applicable to different types of network architectures, many of these are not adequate for all-optical networks. These have unique features and requirements in terms of security and quality of service, thus requiring a much more targeted approach in terms of network management. In this article we consider management issues with particular emphasis on complications that arise due to the unique characteristics and peculiar behaviors of transparent network components. In particular, signal quality monitoring is still a major complication in all-optical networks. Despite new methods for detection and localization of attacks having been proposed, no robust standards or techniques exist to date for guaranteeing the quality of service in these networks. Therefore, sophisticated mechanisms that assist in managing and assessing the proper function of transparent network components are highly desirable. Accordingly, we present an algorithm for multiple attack localization and identification that can participate in some tasks for fault management of all-optical networks     

Requirements Scenarios Formalization Technique: N Versions Towards One Good Version

Using a notion of simulation introduced by de Roever et al. [9], we define a corresponding notion of bisimulation which we will use as a test to detect formality discrepancy between two formal versions of the same informal scenario. We will also use it, combined with the relation part of, as a test to detect discrepancy between two formal scenarios describing two different informal scenarios. We will describe a way of implementing these formality discrepancy tests in the work place. We call it N-version technique for scenario formalization. This technique allows us to (1) detect formality discrepancy between formal scenario versions corresponding to the same scenario, to (2) validate, for the given scenario, the formalization obtained by a specifier against another obtained by another specifier before bothering the stake-holder with problems of the specifier's creation (formalization errors), and to (3) detect formality discrepancy between the formal scenarios of different informal scenarios if their respective spaces share at least one component.