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1.
Multimedia Tools and Applications - New mobile applications need to estimate user activities by using sensor data provided by smart wearable devices and deliver context-aware solutions to users...  相似文献   
2.
Intelligent Service Robotics - Walking robots are considered as a promising solution for locomotion across irregular or rough terrain. While wheeled or tracked robots require flat surface like...  相似文献   
3.
A probability-based approach is presented as the integration of probabilistic methods and deterministic modelling based on the finite element method. An existing finite element software package was linked to an existing probabilistic package to analyse the complex mechanics that occur during the transient non-linear analysis of impact problems. This methodology is applied to a pipe whip analysis of a group-distribution-header, which results from a guillotine break, and subsequent impact with the adjacent building wall; this is a postulated accident for the Ignalina Nuclear Power Plant RBMK-1500 reactors. The uncertainties of material properties, component geometry data and loads were taken into consideration. The probabilities of failure of the impacted header and of the header support-wall were estimated given uncertainties in material properties, geometrical parameters and loading. The software ProFES was used for the probabilistic analysis and the finite element software NEPTUNE for deterministic structural integrity evaluation. The Monte Carlo Simulation, First Order Reliability method and Response Surface method were used in the probabilistic analysis.  相似文献   
4.
Local heat transfer and skin friction around the tube perimeter of coils were studied in airflow. The heat transfer experiments were performed with two different coils D/d = 23 and 15.6, and skin friction experiments were performed with three different coils D/d = 25, 13.3 and 6.67 In the wide range of Re number from 4×103 till 105 . Variation of the local heat transfer around the perimeter and along the tube was defined. The behavior of the shear stresses at the wall and of the flow modes were studied. Investigations of the heat transfer indicated that with the increase of D/d the difference between heat transfer in the initial thermal section and the stabilized heat transfer increases. Investigations of the shear stress and its fluctuations indicated that, in large-curvature coils, the transition from laminar-vortex flow to turbulent flow around the tube perimeter takes place at different values of Re. In the region of the external generatrix of the bend, the transition occurs at smaller Re, whereas a  相似文献   
5.
Recent evidence suggests that I2-imidazoline ligands have neuroprotective properties in animal models of neurodegeneration, such as Alzheimer’s disease (AD). We recently demonstrated that the I2-ligand BU224 reversed memory impairments in AD transgenic mice and this effect was not because of reductions in amyloid-β (Aβ) deposition. In this study, our aim was to determine the therapeutic potential of the powerful analgesic I2-imidazoline ligand CR4056 in the 5xFAD model of AD, since this ligand has been proven to be safely tolerated in humans. Sub-chronic oral administration of CR4056 (30 mg/kg for 10 days) led to an improvement in recognition memory in 6-month-old 5xFAD mice, but not in wild-type littermates, without affecting Aβ levels or deposition. Our results also revealed a change in the profile of microglia by CR4056, resulting in a suppression of pro-inflammatory activated microglia, but increased the density of astrocytes and the expression of ApoE, which is mainly produced by these glial cells. In addition, CR4056 restored fibrinogen extravasation, affecting the distribution of markers of astrocytic end feet in blood vessels. Therefore, these results suggest that CR4056 protects against Aβ-mediated neuroinflammation and vascular damage, and offers therapeutic potential at any stage of AD.  相似文献   
6.
Gas transmission pipeline network is of great importance to any country using natural gases in its various technological processes. However, the usefulness cannot overshadow the threat posed to people and property by the grid failures. In order to quantify the reliability of the grid, se veral widely recognized pipeline incident databases have been established. However, each database contains data about pipelines operated in remote geographical regions with varying soil types, under different incident registration criterion. For a longer time period even in single database, there is variation of these incident registration criteria. Therefore, analysis of an entire sample without regard to the incident criteria change raises suspicions about the validity of resulting inferences. Authors move beyond the qualitative pipeline incident database comparison and provide a methodology for quantitative integration of all available statistical information to improve gas pipeline network reliability evaluation. We develop a new model called Criteria‐dependent Poisson model, which takes into account various incident data collection criteria and extend it to the hierarchical (Bayesian) case when different databases with differing incident registration criteria can be joined in the same analysis. With the real data examples, we demonstrate the applicability of our method, which unfolds itself to be of great usefulness in reliability prediction. The Lithuanian pipeline network failure rate assessment shows the advantages of hierarchical structuring of Criteria‐dependent Poisson model in small sample problems. Copyright © 2015 John Wiley & Sons, Ltd.  相似文献   
7.
Synthesis and properties of the well-defined 3,6-dibromocarbazolyl-containing molecular glasses are reported. They were prepared by the nucleophilic opening of the oxirane ring of 1,3-di(3,6-dibromocarbazol-9-yl)-2-propanol glycidyl ether with aniline, 4-fluoro-, 4-bromoanilines, 2,5-dimercapto-1,3,4-thiadiazole or glycidyl ether of 1,3-di(carbazol-9-yl)-2-propanol with 4,4′-thiobisbenzenethiol and 1,9-nonanedithiol followed by bromination. The obtained materials were examined by various techniques including differential scanning calorimetry, NMR, MS, UV, PL spectrometry. The electrophotographic parameters of the molecular glasses doped with difluoroboron-1,3-bis(4-metoxyphenyl)-1,3-propanedionate have been studied. The electrochemical properties and ionization potentials, measured by electron photoemission method in air, were investigated.  相似文献   
8.
Pattern Analysis and Applications - A correction to this paper has been published: https://doi.org/10.1007/s10044-021-00969-x  相似文献   
9.
Pattern Analysis and Applications - Facial symmetry is a key component in quantifying the perception of beauty. In this paper, we propose a set of facial features computed from facial landmarks...  相似文献   
10.
Objective: To examine dysregulation in biological measures associated with histories of abuse in women and whether women with premenstrual dysphoric disorder (PMDD) differ in their dysregulation. Design: Twenty-five women meeting prospective criteria for PMDD and 42 non-PMDD controls underwent structured interview to determine abuse histories and lifetime Axis I diagnoses, excluding those with current Axis I disorders or using medications. Major Outcome Measures: Plasma cortisol and norepinephrine (NE), heart rate (HR), blood pressure (BP), and vascular resistance index (VRI) were assessed at rest and in response to mental stress. Results: A greater proportion of PMDD women had prior abuse compared with non-PMDD women. Regardless of PMDD status, all abused women had lower plasma NE and higher HRs and tended to have lower plasma cortisol at rest and during stress. Abused women also reported more severe daily emotional and physical symptoms. Greater VRI and BP at rest and during stress were seen only in PMDD women with abuse. Conclusion: There is persistent dysregulation in stress-responsive systems in all abused women that cannot be accounted for by current psychiatric illness or medications, and PMDD women may be differentially more vulnerable to the impact of abuse on measures reflecting α-adrenergic receptor function. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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