甲状腺素T4免疫传感器的研究

报道以甲基丙烯酸羟乙酯与甲基丙烯酸甲酯的共聚物为载体膜材料，研制成非酶标记的Ｔ４免疫传感器，并对载体膜材料的共聚方法及共聚物共聚比与传感器灵敏度的关系进行了探讨。     

刚玉瓷指痕缺陷的研究

本文采用两种不同Al2O3粉为原料，结合Al2O3预烧与材料的生产工艺，对刚玉瓷的指痕缺陷及其对材料性能的影响进行了研究。结果发现：Al2O3粉预烧温度不匀时，部分颗粒（γ-Al2O3）周边存在层错缺陷，激活能的存在，人体中颗粒粘连（团聚）；该团聚体在坯体及烧结体中的残留直接引起烧结体中的结构缺陷，由Al2O3预烧温度高且均匀的粉体制备材料，才能获得具有优良性能的刚玉体。     

三维荧光二阶校正法直接快速测定血浆样中川芎嗪和阿魏酸含量

本文将三维荧光光谱与二阶校正方法相结合用于人体血浆样中的中药药理活性成分川芎嗪和阿魏酸含量的直接测定.尽管预测样存在血浆内源荧光物质的基体干扰,但由于该方法基于“数学分离”的思路和具有“二阶优势”,仍能对荧光光谱严重重叠的血浆样中的目标分析物进行直接同时定量测定,为川芎嗪和阿魏酸在体内的代谢监控及其药效研究提供了一种新思路.获得的预测样中川芎嗪和阿魏酸的平均回收率分别为(95.7±2.2)％和(100.8±2.5)％.该方法简单、快速,结果可靠.     

MOLECULAR APPROACH TO MATERIAL DETACHMENT MECHANISM DURING CHEMICAL MECHANICAL PLANARIZATION

Mechanistic numerical analysis and molecular dynamics (MD) simulation are employed to understand the material detachment mechanism associated with chemical mechanical polishing. We investigate the mechanics of scratch intersection mechanism to obtain a characteristic length scale and compare the theoretical predictions with previous experimental observations on ductile copper discs at the micro-scale. First, an analytical model is developed based on mechanics of materials approach. The analytical model includes the effects of strain hardening during material removal as well as the geometry of indenter tip. In the next step, molecular simulations of the scratch intersection are performed at the atomistic scale. The embedded atom method (EAM) is utilized as the force field for workpiece material and a simplified tool-workpiece interaction is assumed to simulate material removal through scratch intersection mechanism. Both models are utilized to predict a characteristic length of material detachment related to material removal during scratch intersection. The predictions from two approaches are compared with experimental observations in order to draw correlations between experiment and simulation. The insights obtained from this work may assist in understanding the mechanism for chemical mechanical planarization (CMP), and even be applied to other different machining and polishing events.     

社会管理创新视角下审视深圳社区规划

党的十八大报告指出"社会管理创新"应在改善民生和创新管理中加强社会建设。以社区为桥梁,将城市规划与社会管理有效结合,是实现社会管理创新的有效途径。在社会管理创新的视角下,研究整理和分析了深圳特区成立20年来社区发展特征、社区管理沿革以及社区规划与管理的实践成果,从社区规划的编制、实施与管理各阶段提出观点,建议社区规划与现有规划体系衔接,开展编制方法研究;与法定图则联动,增强社区规划的法律约束力;开展社区规划实施策略研究,完善管理机制,以期为我国社会管理创新开拓思路。     

A reusable capacitive immunosensor with a novel immobilization procedure based on 1,6-hexanedithiol and nano-Au self-assembled layers

A novel immobilization procedure of antibody proteins for capacitive immunosensing, based on thiolor sulfur compound (1,6-hexanedithiol, HDT) and colloid Au layers is proposed. The insulating organic monolayer film was first formed by the spontaneous assembly of HDT from solution onto gold. When these thiol-rich surfaces are exposed to Au colloid, the sulfurs form strong bonds to gold nanoparticles, anchoring the clusters to the electrode substrate. After the assembly of gold nanoparticles layer, the original formed organic thiols surface was restored, and a new nano-Au surface was obtained. Thus, the antibody could be immobilized through electrostatic adsorption between nano-Au and the antibody proteins. After use, the formed immunocomplex layer can be rinsed out, via a saline solution with extreme pH. Therefore, the immunosensor can be regenerated repeatedly, highlighting a clear advantage of this new approach with respect to classical immunoassays employing covalent immobilization.     

一台低温穆斯堡尔装置

穆斯堡尔效应在材料科学领域中已获得相当广泛的应用,成为研究材料的微观结构、相变、磁性,氧化及腐蚀等的有力手段之一。在材料科学中,温度是很重要的,它与材料的组织、性能密切相关,因而很需要用以测量高温和低温区穆斯堡尔谱(简称M谱)的装置。本文介绍一种在77-300K范围内可任意变温及恒温的低温装置,它带有两个由Mylar膜制成的     

提高钻井泵陶瓷缸套使用寿命的研究

高压泥浆泵是油田钻井工作台的＂心脏＂,而缸套是泥浆泵的重要磨损部件。工程陶瓷以其高硬度、高耐磨性,耐腐蚀性、表面性能好等优点,在钻井泵缸套中已得到广泛应用。但目前陶瓷缸套的使用寿命相对较短,如何提高陶瓷缸套的使用寿命,已成为陶瓷缸套研究中亟待解决的问题。本研究通过对钻井泵缸套的分析,提出了长寿命陶瓷缸套的要求,从陶瓷材料的选择,力学性能及其微观结构等方面探讨了提高陶瓷缸套使用寿命的方法,为陶瓷缸套生产企业提供改善产品质量的依据和方法。     

簸箕李灌区泥沙远距离输送的研究

目前，引黄灌区渠道集中处理泥沙的模式已受到很大的限制，进一步研究分散处理泥沙的模式是非常必要的。本文在山东簸箕李灌区的基础上，分析水沙资料，总结灌区泥沙输送的经验。     

聚羧酸系高性能减水剂在预拌混凝土中的应用

聚羧酸系高性能减水剂已在上海市预拌混凝土中开始大量应用,但在应用时还存在一些问题,本文介绍了在实际施工中解决混凝土保坍性的方法,在中、低标号混凝土中大量使用的方式,表明聚羧酸系高性能减水剂可在预拌混凝土中普遍使用,具有非常广阔的应用前景。