The Journal of Supercomputing - Accidents often occur in the earth—typhoons, floods, earthquakes, traffic accidents and so on. Whether these accidents can be timely and effectively responded... 相似文献
In distributed systems, user authentication schemes based on password and smart card are widely used to ensure only authorized access to the protected services. Recently, Chang et al. presented an untraceable dynamic-identity-based user authentication scheme with verifiable-password-update. In this research, we illustrate that Chang et al.’s scheme violates the purpose of dynamic-identity contrary to authors’ claim. We show that once the smart card of an arbitrary user is lost, passwords of all registered users are at risk. Using information from an arbitrary smart card, an adversary can impersonate any user of the system. In addition, its password change phase has loopholes and is misguiding. The scheme has no provision for session key agreement and the smart card lacks any verification mechanism. Then we come-up with an improved remote user authentication scheme with the session key agreement, and show its robustness over related schemes. 相似文献
In this digital era, where Internet of Things (IoT) is increasing day by day, use of resource constrained devices is also increasing. Indeed, the features such as low cost, less maintenance, more adaptive to hostile environment, etc. make the wireless multimedia devices to be the best choice as the resource constrained devices. For the security, the end user device requires to establish the session key with the server before transferring the data. Mobile is one of the device having more and more usage as wireless multimedia device in recent years. In 2013, Li et al. proposed an efficient scheme for the wireless mobile communications and claimed it to be secure against various attacks. Recently, Shen et al. claimed that the scheme of Li et al. is still vulnerable to the privileged insider attack, the stolen verifier attack and finally proposed a scheme to withstand the mentioned and other attacks. However, in this paper we claim that the scheme of Shen et al. is still susceptible to the user anonymity, the session specific temporary information attack and the replay attack. In addition, Shen et al.’s scheme requires more time due to many operations. Further, we propose an efficient scheme that is secure against various known attacks and due to reduced time complexity our scheme is a preferred choice for the wireless mobile networks and hence for wireless multimedia systems. 相似文献
Understanding the regulation of the testicular endocrine function leading to testosterone production is a major objective as the alteration of endocrine function is associated with the development of many diseases such as infertility. In the last decades, it has been demonstrated that several endogenous molecules regulate the steroidogenic pathway. Among them, bile acids have recently emerged as local regulators of testicular physiology and particularly endocrine function. Bile acids act through the nuclear receptor FXRα (Farnesoid-X-receptor alpha; NR1H4) and the G-protein-coupled bile acid receptor (GPBAR-1; TGR5). While FXRα has been demonstrated to regulate testosterone synthesis within Leydig cells, no data are available regarding TGR5. Here, we investigated the potential role of TGR5 within Leydig cells using cell culture approaches combined with pharmacological exposure to the TGR5 agonist INT-777. The data show that activation of TGR5 results in a decrease in testosterone levels. TGR5 acts through the PKA pathway to regulate steroidogenesis. In addition, our data show that TGR5 activation leads to an increase in cholesterol ester levels. This suggests that altered lipid homeostasis may be a mechanism explaining the TGR5-induced decrease in testosterone levels. In conclusion, the present work highlights the impact of the TGR5 signaling pathway on testosterone production and reinforces the links between bile acid signaling pathways and the testicular endocrine function. The testicular bile acid pathways need to be further explored to increase our knowledge of pathologies associated with impaired testicular endocrine function, such as fertility disorders. 相似文献
The mobility and openness of wireless communication technologies make Mobile Healthcare Systems (mHealth) potentially exposed to a number of potential attacks, which significantly undermines their utility and impedes their widespread deployment. Attackers and criminals, even without knowing the context of the transmitted data, with simple eavesdropping on the wireless links, may benefit a lot from linking activities to the identities of patient’s sensors and medical staff members. These vulnerabilities apply to all tiers of the mHealth system. A new anonymous mutual authentication scheme for three-tier mobile healthcare systems with wearable sensors is proposed in this paper. Our scheme consists of three protocols: Protocol-1 allows the anonymous authentication nodes (mobile users and controller nodes) and the HSP medical server in the third tier, while Protocol-2 realizes the anonymous authentication between mobile users and controller nodes in the second tier, and Protocol-3 achieves the anonymous authentication between controller nodes and the wearable body sensors in the first tier. In the design of our protocols, the variation in the resource constraints of the different nodes in the mHealth system are taken into consideration so that our protocols make a better trade-off among security, efficiency and practicality. The security of our protocols are analyzed through rigorous formal proofs using BAN logic tool and informal discussions of security features, possible attacks and countermeasures. Besides, the efficiency of our protocols are concretely evaluated and compared with related schemes. The comparisons show that our scheme outperforms the previous schemes and provides more complete and integrated anonymous authentication services. Finally, the security of our protocols are evaluated by using the Automated Validation of Internet Security Protocols and Applications and the SPAN animator software. The simulation results show that our scheme is secure and satisfy all the specified privacy and authentication goals. 相似文献
Authentication schemes are widely used mechanisms to thwart unauthorized access of resources over insecure networks. Several smart card based password authentication schemes have been proposed in the literature. In this paper, we demonstrate the security limitations of a recently proposed password based authentication scheme, and show that their scheme is still vulnerable to forgery and offline password guessing attacks and it is also unable to provide user anonymity, forward secrecy and mutual authentication. With the intention of fixing the weaknesses of that scheme, we present a secure authentication scheme. We show that the proposed scheme is invulnerable to various attacks together with attacks observed in the analyzed scheme through both rigorous formal and informal security analysis. Furthermore, the security analysis using the widely-accepted Real-Or-Random (ROR) model ensures that the proposed scheme provides the session key (SK) security. Finally, we carry out the performance evaluation of the proposed scheme and other related schemes, and the result favors that the proposed scheme provides better trade-off among security and performance as compared to other existing related schemes.