Optimization of quinacridone magenta,Cu-phthalocyanine cyan,and arylide yellow ink films formulated for maximum color gamut

Investigation of ink formulation options with the purpose to obtain color-gamut-optimal set of Cyan Magenta and Yellow CMY inks is reported. Implementation of the thickness dependent Kubelka-Munk model on multiple ink layers having different and well-defined thicknesses, provides characteristic absorption and scattering (K, S ) spectra of the ink ingredients. These data enable accurate computation of the reflectance spectrum and thus the L*a*b* color coordinates for any given ink thickness or substrate. Pigment materials investigated are quinacridone as magenta, copper-phthalocyanine as cyan, and arylide yellow. Scaling the peak of the absorption band to the number of molecules per unit area for the specific pigments studied in this article provides the molar extinction coefficients, 1.21 × 10⁴ , 4.7 × 10⁴ , and 3.3 × 10⁴ cm²/millimole respectively, regardless of the different ink formulations used, in accord with Avogadro's principle. Having a set of three pairs of K, S spectra is used to compute the color gamut of any CMY color combination in the L*a*b* space as a function of ink layer thickness and formulation. Using an iterative algorithm, a color-gamut-optimal set of CMY inks is obtained.     

On the hardness of approximating label-cover

The Label-Cover problem, defined by S. Arora, L. Babai, J. Stern, Z. Sweedyk [Proceedings of 34th IEEE Symposium on Foundations of Computer Science, 1993, pp. 724-733], serves as a starting point for numerous hardness of approximation reductions. It is one of six ‘canonical’ approximation problems in the survey of Arora and Lund [Hardness of Approximations, in: Approximation Algorithms for NP-Hard Problems, PWS Publishing Company, 1996, Chapter 10]. In this paper we present a direct combinatorial reduction from low error-probability PCP [Proceedings of 31st ACM Symposium on Theory of Computing, 1999, pp. 29-40] to Label-Cover showing it NP-hard to approximate to within 2^{(logn)1−o(1)}. This improves upon the best previous hardness of approximation results known for this problem.We also consider the Minimum-Monotone-Satisfying-Assignment (MMSA) problem of finding a satisfying assignment to a monotone formula with the least number of 1's, introduced by M. Alekhnovich, S. Buss, S. Moran, T. Pitassi [Minimum propositional proof length is NP-hard to linearly approximate, 1998]. We define a hierarchy of approximation problems obtained by restricting the number of alternations of the monotone formula. This hierarchy turns out to be equivalent to an AND/OR scheduling hierarchy suggested by M.H. Goldwasser, R. Motwani [Lecture Notes in Comput. Sci., Vol. 1272, Springer-Verlag, 1997, pp. 307-320]. We show some hardness results for certain levels in this hierarchy, and place Label-Cover between levels 3 and 4. This partially answers an open problem from M.H. Goldwasser, R. Motwani regarding the precise complexity of each level in the hierarchy, and the place of Label-Cover in it.     

Induction of favism-like symptoms in the rat: Effects of vicine and divicine in normal and buthionine sulphoximine-treated rats

Rats were fed an adequate or a deficient diet and offered water or buthionine sulphoximine (BSO) solution for 2 weeks, and then the same diets with vicine for another week in experiment 1. BSO in combination with the deficient diet caused a marked decrease in blood glutathione (GSH) and growth retardation but failed to show any effects resulting from supplementation with vicine. In experiment 2 the rats were given an adequate diet and BSO as before, and injected intravenously with divicine (DV). Here again, BSO depressed rat growth, and so did DV. Each of the insults also caused haematological changes, especially a fall in GSH, but the most severe changes appeared in the group treated with both BSO and DV. A decrease in haematocrit and increases in adrenal and spleen weight were also noted. In experiment 3 the rats were injected with different doses of DV, without pretreatment with BSO. The main effect was a drop in blood GSH and haematocrit, and an increase in adrenal and spleen weights, all of which were dose-related. Administration of the higher doses of DV resulted in a severe cyanosis followed by death within a relatively short period of time.     

Multiway merge with constant delay in Concurrent Prolog

Multiway dynamic mergers with constant delay are an essential component of a parallel logic programming language. Previous attempts to defined efficient mergers have required complex optimising compilers and run-time support. This paper proposes a simple technique to implement mergers efficiently. The technique requires an additional data type and the definition of an operation on it. The operation allows multiple processes to access a stream without incurring the cost of searching for the end of stream. It is specified in Concurrent Prolog and is used to define multiple assignment variables using a monitor. The technique forms the basis for stream merging in Logix, a practical programming environment written in Flat Concurrent Prolog.     

The role of charcoal on DTA curves of organo-clay complexes: an overview

DTA of organo-clay complexes supplemented by other thermal analysis methods supplies information on the thermal reactions, properties and stability of the complex, the amount and properties of the adsorbed water in the organo-clay and on the bonding between the organic species and the clay. It is used to identify the mineral to differentiate between various complexes composed of the same clay and the same organic ligand and to establish their composition. During the gradual heating in oxidizing atmospheres the adsorbed organic material is oxidized, giving rise to significant exothermic peaks. DTA curves of organo-clays are divided into three regions: (1) the dehydration of the clay, (2) the thermal oxidation of the organic material and (3) the dehydroxylation of the clay. The exothermic oxidation reaction occurring during the gradual heating of the sample takes place in two steps, in the range 200–500 °C, oxidation of organic hydrogen and formation of water and charcoal, and 400–750 °C, oxidation of charcoal and formation of CO₂. The exothermic peak temperatures depend on the mineral and on the organic compound and on the types of bonding between these two components of the organo-clay complex. The present communication concentrates in the role of the combustion of charcoal in the study of the fine structure of the complex and of the type of associations between the organic compound and the clay.     

A regularized graph layout framework for dynamic network visualization

Many real-world networks, including social and information networks, are dynamic structures that evolve over time. Such dynamic networks are typically visualized using a sequence of static graph layouts. In addition to providing a visual representation of the network structure at each time step, the sequence should preserve the mental map between layouts of consecutive time steps to allow a human to interpret the temporal evolution of the network. In this paper, we propose a framework for dynamic network visualization in the on-line setting where only present and past graph snapshots are available to create the present layout. The proposed framework creates regularized graph layouts by augmenting the cost function of a static graph layout algorithm with a grouping penalty, which discourages nodes from deviating too far from other nodes belonging to the same group, and a temporal penalty, which discourages large node movements between consecutive time steps. The penalties increase the stability of the layout sequence, thus preserving the mental map. We introduce two dynamic layout algorithms within the proposed framework, namely dynamic multidimensional scaling and dynamic graph Laplacian layout. We apply these algorithms on several data sets to illustrate the importance of both grouping and temporal regularization for producing interpretable visualizations of dynamic networks.     

Hyperprolactinemia in end‐stage renal disease and effects of frequent hemodialysis

Introduction: End‐stage renal disease is associated with elevations in circulating prolactin concentrations, but the association of prolactin concentrations with intermediate health outcomes and the effects of hemodialysis frequency on changes in serum prolactin have not been examined. Methods: The FHN Daily and Nocturnal Dialysis Trials compared the effects of conventional thrice weekly hemodialysis with in‐center daily hemodialysis (6 days/week) and nocturnal home hemodialysis (6 nights/week) over 12 months and obtained measures of health‐related quality of life, self‐reported physical function, mental health and cognition. Serum prolactin concentrations were measured at baseline and 12‐month follow‐up in 70% of the FHN Trial cohort to examine the associations among serum prolactin concentrations and physical, mental and cognitive function and the effects of hemodialysis frequency on serum prolactin. Findings: Among 177 Daily Trial and 60 Nocturnal Trial participants with baseline serum prolactin measurements, the median serum prolactin concentration was 65 ng/mL (25th–75th percentile 48–195 ng/mL) and 81% had serum prolactin concentrations >30 ng/mL. While serum prolactin was associated with sex (higher in women), we observed no association between baseline serum prolactin and age, dialysis vintage, and baseline measures of physical, mental and cognitive function. Furthermore, there was no significant effect of hemodialysis frequency on serum prolactin in either of the two trials. Discussion: Serum prolactin concentrations were elevated in the large majority of patients with ESRD, but were not associated with several measures of health status. Circulating prolactin levels also do not appear to decrease in response to more frequent hemodialysis over a one‐year period.     

Effects of pH on rhodopsin photointermediates from lumirhodopsin to metarhodopsin II

Time-resolved absorption difference spectra of membrane suspensions of bovine rhodopsin at pH 5, 6, 7, 8, 9, and 10 were collected in the time range from 1 micro s to 200 ms after laser photolysis with 7-ns pulses of 477-nm light. The data were analyzed using singular value decomposition (SVD) and global exponential fitting. At pH 7 the data agree well with previously obtained data (Thorgeirsson et al. (1993) Biochemistry 32, 13861-13872) with fits improved at all pH's by inclusion of a small component due to an absorbance change caused by rotational diffusion which is detectable even at magic angle polarization. A "square scheme" suggested to best explain the previous data, which involves two branches following decay of the lumi intermediate with pathways (1) lumi --> MI480 right harpoon over left harpoon MII and (2) lumi right harpoon over left harpoon MI380 --> MII, could be confirmed throughout the entire pH range. However, to account for the increased rate of the MII --> MI480 reaction in path 1 for rising pH values, we propose that the MII in the square scheme consists of deprotonated MII and protonated MIIH+ forms in rapid equilibrium with each other, resulting in an extended square scheme and increasing the number of 380-nm products from two to three. In addition to the kinetic processes described by the extended square scheme, above pH 8 fast ( approximately 10 micro s) and slow ( approximately 50 ms) components were found. The fast component was assigned to the decay of a blue-shifted lumi intermediate, and the slow component, resolvable only at pH 10, was assigned to formation of a 450 nm absorbing photoproduct.