Survival and movement of enterovirus in connection with land disposal of sludges

Coxsackievirus and tritiated water were added to municipal sludges which were placed on lysimeters containing sandy soil or clay soil. It took 23 weeks during a normal Danish winter to inactivate virus from an initial 10⁶tcid₅₀/g sludge to a not demonstrable level. Irrespective of sludge and soil type no virus was demonstrated in the leachate water. The rainfall during December–May was 300 mm.     

Prediction of proteasome cleavage motifs by neural networks

We present a predictive method that can simulate an essentialstep in the antigen presentation in higher vertebrates, namelythe step involving the proteasomal degradation of polypeptidesinto fragments which have the potential to bind to MHC ClassI molecules. Proteasomal cleavage prediction algorithms publishedso far were trained on data from in vitro digestion experimentswith constitutive proteasomes. As a result, they did not takeinto account the characteristics of the structurally modifiedproteasomes—often called immunoproteasomes—foundin cells stimulated by     

Microscopic comparison of the synovial changes in posttraumatic synovitis and osteoarthritis

The similarity of the histopathologic changes in posttraumatic synovitis and osteoarthritis suggests that similar etiologic agents, possibly macro- and microtraumata, were pathogenetic factors in common.