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1.
2.
FL Kiselev 《Canadian Metallurgical Quarterly》1997,42(6):248-251
The migration of substances from rubber packaging materials into drug products can be significant with certain packaging materials in contact with organic solvent systems. Recommendations for testing drug products for leachables are continually evolving to address new developments. Testing packaging materials using simulated solvents is not always an acceptable protocol for the pharmaceutical industry. We describe a rational strategy for evaluation of the drug product for packaging extractables. A profile of the extractables from rubber packaging materials was made with a range of organic solvents and stress conditions to provide information on substances to target in the drug product. The drug product was evaluated to determine if the matrix would cause interferences that might inhibit detection of the found extractables. Analytical methods were selected based on these findings. The procedures were validated according to FDA guidelines. A stability program using time and storage conditions as variables provided information for acceptance criteria. This same strategy can be used on other types of pharmaceuticals and packaging materials. 相似文献
3.
Stekloplastik—Sertifikat Corporation Moscow. Translated from Khimicheskie Volokna, No. 2, pp. 58–59, March–April, 1994. 相似文献
4.
Results of a study are reported on the utilization of ground vulcanizate, which is a waste product of rubber prcoessing plants. Loaded stocks of various commercial rubbers act as objects for the study. Talc, kaolin, silicon dioxide, and furnace carbon black are used as fillers. According to the results of a study on the effect of the amount of rubber crumb, an increase in the content of unmodified crumb leads to a decrease in tear resistance that is associated with poor wettability. To increase wettability, we use organosilicon couplings. It is shown that the addition of vulcanizate to rubber stocks, together with highly dispersed fillers treated with organosilicon couplings, leads to a significant increase in tear resistance and makes it possible to significantly reduce the cost of production and utilization. 相似文献
5.
V. F. Chirikhin Yu. N. Tuluevskii V. G. Mizin A. D. Kiselev V. B. Beizerov V. G. Milyuts 《Metallurgist》1988,32(3):114-116
Orsk-Khalilovo Metallurgical Combine. Scientific-Research Institute of Metallurgy. Translated from Metallurg, No. 3, pp. 43–45, March, 1988. 相似文献
6.
On the basis of the isomorphism of critical phenomena, the behavior of transport properties of binary mixtures in the vicinity of the vapor-liquid critical line is considered. In particular, the renormalization of the singularity of the thermal conductivity in dilute critical solutions has been analyzed in detail. It is shown that the behavior of the thermal conductivity is determined by the critical background, i.e., the fluctuation-induced regular part, which diverges at the critical point of a solvent. 相似文献
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8.
I. N. Sorokin T. M. Golovina D. S. Rutman A. D. Popov V. M. Ust'yantsev V. A. Perepelitsyn T. É. Khairov N. V. Latypova N. I. Cherneta M. V. Galkin V. N. Kiselev A. E. Fadeev 《Refractories and Industrial Ceramics》1984,25(5-6):293-296
Conclusions The possibility of obtaining clinker from high-alumina cement by melting a mixture of lime and technical alumina in an electric-arc furnace at the Klyuchevsk Ferroalloy Plant has been shown.The high-alumina cement obtained from fused clinker is significantly better in its physicochemical properties than the cement produced on the basis of the lime-alumina slags from the ferroalloy industry.Translated from Ogneupory, No. 5, pp. 25–27, May, 1984. 相似文献
9.
V. M. Boiko V. P. Kiselev S. P. Kiselev A. N. Papyrin S. V. Poplavskii V. M. Fomin 《Combustion, Explosion, and Shock Waves》1996,32(2):191-203
The present paper is devoted to experimental and theoretical investigation of shock-wave propagation in a mixture of a gas and solid particles with clearly defined boundaries of the two-phase region (cloud of particles). The effect of qualitative transformation of supersonic flow behind a shock wave in a cloud of particles is shown experimentally and substantiated theoretically for volume concentrations of the dispersed phase of 0.1–3%.Translated from Fizika Goreniya i Vzryva, Vol. 32, No. 2, pp. 86–99, March–April, 1996. 相似文献
10.
Combustion, Explosion, and Shock Waves - Results of numerical simulations of fracture of titanium and aluminum nanocrystals by the molecular dynamics method are reported. The... 相似文献