Parameter Uncertainty and Policy Intensity: Some Extensions and Suggestions for Further Work

The effects of parameter uncertainty on optimal policy have been a matter of interest for academics, and even for some policymakers, for a long time. Two lines of literature have developed analytical results on this matter. The first line uses static models and the second dynamic models. In this dynamic line most of the results are confined to models with a single state and a single control variable. In this paper we want to encourage the analysis of more general dynamic cases. To do so, the results in the dynamic line are extended from one-state and one-control finite horizon models to models with a pair of control variables. We then discuss some of the hurdles which must be surmounted for the results to be made more general and suggests some lines for further research. JEL classification: C61; E61     

Frequency of molecular alterations in heterozygous beta-thalassemia in southern Spain and their relation to the hematologic phenotype

INTRODUCTION: Heterozygous beta-thalassemia manifests hematologically with microcytosis, reduced red blood cell hemoglobin concentration and high hemoglobin A2 levels. Almost all molecular alterations are due to point mutations. We attempt to determinate the frequency of that mutations in the Oriental Andalusia Area, and its relationship with the hematological phenotype. PATIENTS AND METHODS: We have studied 45 heterozygous patients. DNA samples were amplified by PCR, using the printers CD7 and HI1. A 16 Kb fragment corresponding to beta globin gene was obtained and analyzed by Dot Blot assay and hybridized with allelic specific oligonucleotide (ASO) probes to detect the 6 more frequent mutations found in the South of Spain. RESULTS: Codon 39 nonsense mutation (31.1%) was the most frequent finding followed by IVS-1 NT 110 (26.7%). The relationship between hematological parameters and molecular mutations concluded that IVS-I NT 6 mutation developed a minimal anemia. DISCUSSION: From the practical point of view, this study indicates that we were able to detect more than 90% of heterozygous beta-tal. with 5 out of 6 ASO probes used in this work. Thus, our data also provides a further implication in prenatal diagnosis.     

A flexible architecture for distributed knowledge based systems with nomadic access through handheld devices

Nowadays any Knowledge Based System (KBS) realization needs of intercommunication among distributed components and to use non-connected and distributed data sources, which poses several challenges to the classical Artificial Intelligence field of KBS.

The multiagent paradigm and the use of ontologies are considered to be suitable tools to face the problems of designing and developing today KBS. On the other hand, using such networked KBS through handheld devices makes more efficient exploitation and interaction with the system.

This paper presents an open and flexible architecture for a distributed KBS and an application of it to construct a system for Psychological Disorders consulting, the so called PDA² (Psychological Disorder Assistant through PDA). We analyze the main features of the architecture as well as the agent tools we may use to construct it. Additionally, we present a support ontology for Psychological Disorders.     

Efficient procedure for computing fields created by current modes

An efficient method for computing the fields of large scatterers is presented. The current is expanded in terms of modes defined as complex exponential functions. The modes are represented efficiently by means of spline functions. Analytical expressions have been obtained to compute efficiently the fields due to the current modes.     

Theory,design, and evaluation of the rotating polarizer interferometer

We present the results of modeling the response of a Rotating Polarizer Interferometer (RPI), an actual design and the evaluation of it. The RPI was introduced almost 10 years ago by Erickson [1] and since then it has not received too much attention from the millimeter wave community despite its very attractive characteristics, this is perhaps due to a lack of proven designs to encourage potential users. Here we show that with proper design equations a predictable result can be achieved and that a working device with a low-loss dielectric filling (Teflon) is feasible     

Improving manufacturing by cost-effective process modeling

Computer-aided engineering tools are routinely used to simulate forging and heat-treatment operations and to perform thermal and stress analyses. This review gives a few examples of the current uses of process modeling tools and outlines some developing capabilities and near-term applications.     

Failure mechanism study of anisotropic conductive film (ACF) packages

Anisotropic conductive film (ACF) consists of an adhesive polymer matrix with dispersed conductive particles. In flip-chip technology, ACF has been used in place of solder and underfill for chip attachment to glass or organic substrates. The filler particles establish the electrical contacts between the interconnecting areas. ACF flip-chip bonding provides finer pitch, higher package density, reduced package size and improved lead-free compatibility. Nevertheless, the interconnection is different from traditional solder joints, the integrity and durability of the ACF interconnects have major concerns. Failures in anisotropic conductive film (ACF) parts have been reported after temperature cycling, moisture preconditioning and autoclave. The failures have not been well understood and have been attributed to a wide variety of causes. This paper investigates the failure mechanism of ACF using finite element simulation. From a failure-initiation point of view, the response of ACF packages to environmental (temperature and humidity) exposure is very different from standard underfilled packages. These differences cause the ACF package to fail in different ways from an underfilled package. Simulation results have shown that moisture-induced ACF swelling and delamination is the major cause of ACF failure. With moisture absorption, the loading condition at the interface is tensile-dominant, which corresponds to lower interface toughness (or fracture resistance). This condition is more prone to interface delamination. Therefore, the reliability of ACF packages is highly dependent on the ACF materials. The paper suggests a new approach toward material selection for reliable ACF packages. This approach has very good correlation with experimental results and reliability testing of various ACF materials.     

A Simple Experimental Technique to Measure Tortuosity in Packed Beds

In this article, a simple and inexpensive experimental technique easy to build in laboratory, for the measurement of tortuosity of a packed bed of inert particles, is described. Experimental values of the tortuosity were obtained with four different packed beds of sand. The experimental results obtained are in good agreement with the theoretical values of tortuosity in a porous media; and the data reported showed the tortuosity to increase with decrease in the void fraction of the packed bed as expected.     

Molecular Diffusion Coefficients of Organic Compounds in Water at Different Temperatures

Molecular (or tracer) diffusion coefficient data were obtained for 2-naphthol, benzoic acid, salicylic acid, camphor, and cinnamic acid in water at temperatures that differ significantly from ambient value. Experimental values were determined for the dissolution of 2-naphthol in water at 283 to 368 K, of benzoic acid in water at 283 to 338 K, of salicylic acid in water at 283 to 343 K, of camphor in water at 283 to 318 K, and of cinnamic acid in water at 283 to 318 K. Empirical correlations are presented for the prediction of molecular diffusion coefficient over the entire range of temperatures studied, and they are shown to predict the obtained data with very good accuracy.