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排序方式: 共有283条查询结果,搜索用时 31 毫秒
1.
KJ Shon M Grilley R Jacobsen GE Cartier C Hopkins WR Gray M Watkins DR Hillyard J Rivier J Torres D Yoshikami BM Olivera 《Canadian Metallurgical Quarterly》1997,36(31):9581-9587
A paralytic peptide, psi-conotoxin Piiie has been purified and characterized from Conus purpurascens venom. Electrophysiological studies indicate that the peptide inhibits the nicotinic acetylcholine receptor (nAChR). However, the peptide does not block the binding of alpha-bungarotoxin, a competitive nAChR antagonist. Thus, psi-conotoxin Piiie appears to inhibit the receptor at a site other than the acetylcholine-binding site. As ascertained by sequence analysis, mass spectrometry, and chemical synthesis, the peptide has the following covalent structure: HOOCCLYGKCRRYOGCSSASCCQR* (O = 4-trans hydroxyproline; * indicates an amidated C-terminus). The disulfide connectivity of the toxin is unrelated to the alpha- or the alphaA-conotoxins, the Conus peptide families that are competitive inhibitors of the nAChR, but shows homology to the mu-conotoxins (which are Na+ channel blockers). 相似文献
2.
In-Jin Shon 《Metals and Materials International》1997,3(3):199-202
The influence of an electric field on the combustion synthesis of Ti5Si3-x Nb composites (0≤ x ≤0.8) was investigated. Composites where x ≥ 0.8 can only be synthesized in the presence of a field.
In the absence of a field, those systems where x=0.8 can result in a non-steady combustion wave causing an incomplete reaction.
That is, an unstable wave propagates to the middle of the sample and then becomes extinguished. The wave velocity of the Ti5Si3-x Nb composites slightly increases with the imposition of an external electric field across the sample. 相似文献
3.
Hwan-Cheol Kim In-Jin Shon J.E. Garay Z.A. Munir 《International Journal of Refractory Metals and Hard Materials》2004,22(6):257-264
The rapid sintering of nano-structured WC hard materials in a short time is introduced with a focus on the manufacturing potential of this spark plasma sintering process. The advantage of this process allows very quick densification to near theoretical density and prohibition of grain growth in nano-structured materials. A dense pure WC hard material with a relative density of up to 97.6% was produced with simultaneous application of 60 MPa pressure and electric current of 2800 A within 2 min. A larger current caused a higher rate of temperature increase and therefore a higher densification rate of the WC powder. The finer the initial WC powder size the higher is the density and the better are the mechanical properties. The fracture toughness and hardness values obtained were 6.6 MPa m1/2 and 2480 kg/mm2, respectively under 60 MPa pressure and 2800 A using 0.4 μm WC powder. 相似文献
4.
Krishnamurthy Adarsh Khardekar Rahul McMains Sara Haller Kirk Elber Gershon 《IEEE transactions on visualization and computer graphics》2009,15(4):530-543
We present algorithms for evaluating and performing modeling operations on NURBS surfaces using the programmable fragment processor on the Graphics Processing Unit (GPU). We extend our GPU-based NURBS evaluator that evaluates NURBS surfaces to compute exact normals for either standard or rational B-spline surfaces for use in rendering and geometric modeling. We build on these calculations in our new GPU algorithms to perform standard modeling operations such as inverse evaluations, ray intersections, and surface-surface intersections on the GPU. Our modeling algorithms run in real time, enabling the user to sketch on the actual surface to create new features. In addition, the designer can edit the surface by interactively trimming it without the need for retessellation. Our GPU-accelerated algorithm to perform surface-surface intersection operations with NURBS surfaces can output intersection curves in the model space as well as in the parametric spaces of both the intersecting surfaces at interactive rates. We also extend our surface-surface intersection algorithm to evaluate self-intersections in NURBS surfaces. 相似文献
5.
Krishnamurthy A McMains S Haller K 《IEEE transactions on visualization and computer graphics》2011,17(6):729-742
We present practical algorithms for accelerating distance queries on models made of trimmed NURBS surfaces using programmable Graphics Processing Units (GPUs). We provide a generalized framework for using GPUs as coprocessors in accelerating CAD operations. By supplementing surface data with a surface bounding-box hierarchy on the GPU, we answer distance queries such as finding the closest point on a curved NURBS surface given any point in space and evaluating the clearance between two solid models constructed using multiple NURBS surfaces. We simultaneously output the parameter values corresponding to the solution of these queries along with the model space values. Though our algorithms make use of the programmable fragment processor, the accuracy is based on the model space precision, unlike earlier graphics algorithms that were based only on image space precision. In addition, we provide theoretical bounds for both the computed minimum distance values as well as the location of the closest point. Our algorithms are at least an order of magnitude faster and about two orders of magnitude more accurate than the commercial solid modeling kernel ACIS. 相似文献
6.
Porous Materials: Direct Laser Writing of Low‐Density Interdigitated Foams for Plasma Drive Shaping (Adv. Funct. Mater. 43/2017)
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James S. Oakdale Raymond F. Smith Jean‐Baptiste Forien William L. Smith Suzanne J. Ali Leonardus B. Bayu Aji Trevor M. Willey Jianchao Ye Anthony W. van Buuren Matthew A. Worthington Shon T. Prisbrey Hye‐Sook Park Peter A. Amendt Theodore F. Baumann Juergen Biener 《Advanced functional materials》2017,27(43)
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Laura Chekli Sherub Phuntsho Maitreyee Roy Enzo Lombi Erica Donner Ho Kyong Shon 《Water research》2013,47(13):4585-4599
Iron nanoparticles are becoming increasingly popular for the treatment of contaminated soil and groundwater; however, their mobility and reactivity in subsurface environments are significantly affected by their tendency to aggregate. Assessing their stability under environmental conditions is crucial for determining their environmental fate. A multi-method approach (including different size-measurement techniques and the DLVO theory) was used to thoroughly characterise the behaviour of iron oxide nanoparticles (Fe2O3NPs) under environmentally relevant conditions. Although recent studies have demonstrated the importance of using a multi-method approach when characterising nanoparticles, the majority of current studies continue to use a single-method approach.Under some soil conditions (i.e. pH 7, 10 mM NaCl and 2 mM CaCl2) and increasing particle concentration, Fe2O3NPs underwent extensive aggregation to form large aggregates (>1 μm). Coating the nanoparticles with dissolved organic matter (DOM) was investigated as an alternative “green” solution to overcoming the aggregation issue instead of using the more commonly proposed polyelectrolytes. At high concentrations, DOM effectively covered the surface of the Fe2O3NPs, thereby conferring negative surface charge on the particles across a wide range of pH values. This provided electrostatic stabilisation and considerably reduced the particle aggregation effect. DOM-coated Fe2O3NPs also proved to be more stable under high ionic strength conditions. The presence of CaCl2, however, even at low concentrations, induced the aggregation of DOM-coated Fe2O3NPs, mainly via charge neutralisation and bridging. This has significant implications in regards to the reactivity and fate of these materials in the environment. 相似文献
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