OsMre11 Is Required for Mitosis during Rice Growth and Development

Meiotic recombination 11 (Mre11) is a relatively conserved nuclease in various species. Mre11 plays important roles in meiosis and DNA damage repair in yeast, humans and Arabidopsis, but little research has been done on mitotic DNA replication and repair in rice. Here, it was found that Mre11 was an extensively expressed gene among the various tissues and organs of rice, and loss-of-function of Mre11 resulted in severe defects of vegetative and reproductive growth, including dwarf plants, abnormally developed male and female gametes, and completely abortive seeds. The decreased number of cells in the apical meristem and the appearance of chromosomal fragments and bridges during the mitotic cell cycle in rice mre11 mutant roots revealed an essential role of OsMre11. Further research showed that DNA replication was suppressed, and a large number of DNA strand breaks occurred during the mitotic cell cycle of rice mre11 mutants. The expression of OsMre11 was up-regulated with the treatment of hydroxyurea and methyl methanesulfonate. Moreover, OsMre11 could form a complex with OsRad50 and OsNbs1, and they might function together in non-homologous end joining and homologous recombination repair pathways. These results indicated that OsMre11 plays vital roles in DNA replication and damage repair of the mitotic cell cycle, which ensure the development and fertility of rice by maintaining genome stability.     

远距离移动负载高压电源的设计

为对远距离的直流移动负载进行供电,须考虑损耗、体积、指标等一系列的问题。要解决远距离损耗大的问题,则须采用在始端升压、负载端降压的措施;要使负载端的变换器体积小,则须提高系统频率,在变换器中采用高频变压器;要满足整个系统的指标,则须完成从部分到整体的设计过程。在此基础上,此供电电源采用AC/DC/DC变换的过程,始端变换器中采用三相PWM斩波稳压与12脉波整流相结合输出高压直流,然后经过远距离的电缆,负载端DC/DC变换器采用半桥三电平结构进行直流降压后为移动负载供电。文中分别对两个部分的拓扑以及工作原理进行了理论分析与仿真,仿真结果表明,供电电源采用这样的拓扑结构能够得到稳定的直流电压,并且不会影响始端的交流指标。     

深度卷积神经网络在心音分类方法中的应用

通过分析心音信号对心脏早期的病理状态进行确诊具有重要的意义。提出了一种基于深度卷积神经网络的心音分类方法。将心音信号转化成具有时频特性的梅尔频谱系数（Mel Frequency Spectral Coefficient,MFSC）特征图,将其作为深度卷积神经网络模型的输入;利用深度卷积神经网络对MFSC特征图进行训练,引入中心损失函数建立最优的深度学习模型;测试阶段,先将心音信号转换成多张二维MFSC特征图,然后利用训练好的深度学习模型对其分类,最后利用多数表决原则判断心音信号的类别。针对人工标注的训练样本有限,导致模型训练正确率不高的问题,以心音的二维MFSC特征图为对象分别从时间域和频率域进行随机屏蔽处理进而扩充训练样本。实验结果表明,该方法在PASCAL心音数据集上进行测试,对正常、杂音、早搏三种心音的分类性能明显优于现有最好的方法。     

新时期解决农村群体性事件的应然、实然和必然

近年来,我国农村群体性事件频频发生并呈现出螺旋上升态势。处于社会转型期的农村,其各种矛盾冲突提档升级,群体性事件频频见诸报端,愈演愈烈,不仅严重制约着社会主义和谐新农村建设的步伐,也给基层政府的治理提出了严峻考验。以新时期农村经济社会的发展趋势为时代背景,深度挖掘解决农村群体性事件的应然之义,探寻新时期农村群体性事件的实然之路,提出解决农村群体性事件的必然之策,为新时期农村群体性事件的政府治理提供理论依据。     

Plasmon enhancement for Vernier coupled single-mode lasing from ZnO/Pt hybrid microcavities

It is essential to develop a single mode operation and improve the performance of lasing in order to ensure practical applicability of microlasers and nanolasers.In this paper,two hexagonal microteeth with varied nanoscaled air-gaps of a ZnO microcomb are used to construct coupled whispering-gallery cavities.This is done to achieve a stable single mode lasing based on Vernier effect without requiring any complicated or sophisticated manipulation to achieve positioning with nanoscale precision.Optical gain and the corresponding ultraviolet lasing performance were improved greatly through coupling with localized surface plasmons of Pt nanoparticles.The ZnO/Pt hybrid microcavities achieved a seven-fold enhancement of intensity of single mode lasing with higher sidemode suppression ratio and lower threshold.The mechanism that led to this enhancement has been described in detail.     

二板式注塑机合模机构的振动测试

为提高大型二板注塑机合模机构的工作可靠性,对注塑成型完整周期过程中的注塑机动、定模板进行振动与冲击加速度测试,确定了振动信号中的低、高频成分的来源。低频振动是影响合模过程的主要振动信号,通过数字滤波和数值积分技术,评定了动、定模板的轴向振动加速度和最大摆动角度,为合模机构的减振优化和质量控制提供技术基础。     

Multistage System Planning for Hydrogen Production and Distribution

Hydrogen is an energy carrier that has the potential to improve the sustainability of transportation fuels and reduce oil dependence. This paper presents a stochastic dynamic programming model for sequentially building a hydrogen production and distribution system. The decision variables are the sequence and locations of the central production sites and the corresponding distribution systems from supply to demand sites. A case study based on the geographic setting of Northern California is included, in which the hydrogen is produced via coal gasification and transported from plant to city gates (demand sites) by cryogenic liquid hydrogen trucks. Future demands for hydrogen are modeled as uncertain parameters, with an assumption that hydrogen fuel cell vehicle (HFCV) market penetration rate increases from 1% to 25% over a 20-year period. This model provides multistage decision support for long term transportation energy planning at national and regional levels.     

Solving Stochastic Transportation Network Protection Problems Using the Progressive Hedging-based Method

This research focuses on pre-disaster transportation network protection against uncertain future disasters. Given limited resources, the goal of the central planner is to choose the best set of network components to protect while allowing the network users to follow their own best-perceived routes in any resultant network configuration. This problem is formulated as a two-stage stochastic programming problem with equilibrium constraints, where the objective is to minimize the total expected physical and social losses caused by potential disasters. Developing efficient solution methods for such a problem can be challenging. In this work, we will demonstrate the applicability of progressive hedging-based method for solving large scale stochastic network optimization problems with equilibrium constraints. In the proposed solution procedure, we solve each modified scenario sub-problem as a mathematical program with complementary constraints and then gradually aggregate scenario-dependent solutions to the final optimal solution.     

B掺杂p型SiGe合金的制备与热电性能表征

以一定化学计量比均匀混合的Si、Ge、B混合粉末为原材料,使用放电等离子烧结(SPS)一步法合金化制备了p型Si₈₀Ge₂₀B_x(x=0.5,1.0,2.0)合金热电材料,并对样品的组成、微观形貌、热电性能进行了表征与分析。结果表明,放电等离子烧结过程实现原位合金化并烧结为块体材料。随着B掺杂量的增加,电导率明显提升,热导率显著下降,当温度为950K时,热导率为1.79W/(m·K)。在1050K时,ZT值达到了0.899。球磨和掺杂的协同作用使得SiGe合金基体内产生不同类型的缺陷特征而散射不同波长的声子,导致硅锗合金热导率的降低。     

双腐蚀缺陷油气管道剩余强度分析

以X60双腐蚀缺陷油气管道为研究对象,借助ANSYS软件,分析双腐蚀缺陷半径和缺陷深度对其等效应力和剩余强度的影响。结果表明:随着轴向位置的增加,双腐蚀缺陷管道等效应力在屈服极限与抗拉极限之间变化;随着缺陷半径的增大,剩余强度呈增加的趋势,安全性增强;随着缺陷深度的增大,剩余强度呈减小的趋势,安全性降低。所得结论对于油气管道的腐蚀安全评价有一定的参考意义。