Interactive hybrid (symbolic-numeric) system approach to near optimal design of mechanical components

A hybrid symbolic-numeric system, referred to as OPTDEX, (Optimal Design Expert) for the optimal design of mechanical components and systems has been developed. The system is written in Golden Common LISP and IBM Professional (Ryan-McFarland) FORTRAN for execution on the IBM PC/AT microcomputer. Graphical output has been implemented using the Graphical Kernal System (GKS) standard. This microcomputer-based implementation makes the system particularly attractive as an easily accessible, low-cost engineering analysis and design tool.Experience with the system indicates that the time required to achieve, at least partially optimized engineering design solutions, is similar to that which may be expected with standard, nonoptimization-based microcomputer computation. Any added computational time may be justified and subsequently offset by increased long-term design efficacy.The OPTDEX protocol (Fig. 1) assumes a modular form, whereby each level can be modified, updated, and enhanced independently of the others to accommodate various design philosophies and the subdivision of large-scale design problems. A design cell approach has been adopted that has the capability of addressing the design of various mechanical components and systems. The current version of the OPTDEX design cell library, which is undergoing revision and expansion, includes speed reducer, bearing, coupling, and shaft design capabilities.This modular structure and generalized design cell approach, which underlies the OPTDEX system, establishes the basis of a formalized methodology for mechanical engineering design, which may be extended to include other design-related disciplines as well. For example, with the addition of appropriate design cells, the system can be configured for VLSI circuit design in electrical engineering, scheduling, and job routing in industrial engineering, and structural design in civil engineering.     

Synergistic Effect of PVDF-Coated PCL-TCP Scaffolds and Pulsed Electromagnetic Field on Osteogenesis

Bone exhibits piezoelectric properties. Thus, electrical stimulations such as pulsed electromagnetic fields (PEMFs) and stimuli-responsive piezoelectric properties of scaffolds have been investigated separately to evaluate their efficacy in supporting osteogenesis. However, current understanding of cells responding under the combined influence of PEMF and piezoelectric properties in scaffolds is still lacking. Therefore, in this study, we fabricated piezoelectric scaffolds by functionalization of polycaprolactone-tricalcium phosphate (PCL-TCP) films with a polyvinylidene fluoride (PVDF) coating that is self-polarized by a modified breath-figure technique. The osteoinductive properties of these PVDF-coated PCL-TCP films on MC3T3-E1 cells were studied under the stimulation of PEMF. Piezoelectric and ferroelectric characterization demonstrated that scaffolds with piezoelectric coefficient d₃₃ = −1.2 pC/N were obtained at a powder dissolution temperature of 100 °C and coating relative humidity (RH) of 56%. DNA quantification showed that cell proliferation was significantly enhanced by PEMF as low as 0.6 mT and 50 Hz. Hydroxyapatite staining showed that cell mineralization was significantly enhanced by incorporation of PVDF coating. Gene expression study showed that the combination of PEMF and PVDF coating promoted late osteogenic gene expression marker most significantly. Collectively, our results suggest that the synergistic effects of PEMF and piezoelectric scaffolds on osteogenesis provide a promising alternative strategy for electrically augmented osteoinduction. The piezoelectric response of PVDF by PEMF, which could provide mechanical strain, is particularly interesting as it could deliver local mechanical stimulation to osteogenic cells using PEMF.     

Adaptive control optimization in end milling using neural networks

In this paper, we propose an architecture with two different kinds of neural networks for on-line determination of optimal cutting conditions. A back-propagation network with three inputs and four outputs is used to model the cutting process. A second network, which parallelizes the augmented Lagrange multiplier algorithm, determines the corresponding optimal cutting parameters by maximizing the material removal rate according to appropriate operating constraints. Due to its parallelism, this architecture can greatly reduce processing time and make real-time control possible. Numerical simulations and a series of experiments are conducted on end milling to confirm the feasibility of this architecture.     

Measuring virtual experience in a three-dimensional virtual reality interactive simulator environment: a structural equation modeling approach

With the rapid development of the VR market, virtual experience has increasingly been the object of study in recent years. A growing number of studies have reported the positive effect that virtual experience can have on a user’s mood and loyalty. However, few studies have investigated the influence of the mechanism of virtual experience on users’ mood and loyalty. To compensate for this research gap, this study aims to evaluate consumers’ virtual experience by examining the flow state in a virtual environment. A total of 368 valid questionnaires were collected, and a structural equation modeling approach was employed in the data analysis. The study reveals that forming flow involves many factors: the intrinsic characteristics of the mediated environment, the consumer’s assumptions and perceptions prior to entering the flow state, the stage at which the customer enters the flow state, and the consequences of the flow experience.     

Rapid Microarray System For Passive Batch-Filling and In-Parallel-Printing Protein Solutions

This paper develops a novel microcontact printing system for printing tens of protein solutions into an array with batch filling and parallel printing. This printing system consists of micro filling and micros tamp chips. The micro filling chip can simultaneously transfer numerous protein solutions into the micros tamp chip in seconds by capillary force without cross contamination while preserving the functionality of proteins. Different proteins can be dispensed into the corresponding channels and driven into the tips of the microstamps. The microstamp can then be brought to contact with the substrate to produce bio fluid spot arrays. Teflon patterns are applied on both micro filling and microstamp chips to prevent cross contamination during filling. Thirty-six proteins can be printed in parallel with a spot size variation of less than 5%. This device has a potential to be expanded to a passive and high-throughput system for simultaneously printing hundreds of bio fluid spots to form dense arrays for diagnosing disease or screening for drugs.     

Wireless link prediction and triggering using modified Ornstein–Uhlenbeck jump diffusion process

Through time domain observation, typical wireless signal strength values seems to exhibit some forms of mean-reverting and discontinuous “jumps” behaviour. Motivated by this fact, we propose a wireless link prediction and triggering (LPT) technique using a modified mean-reverting Ornstein–Uhlenbeck (OU) jump diffusion process. The proposed technique which we refer as OU-LPT is an integral component of wireless mesh network monitoring system developed by ICT FP7 CARrier grade wireless MEsh Network project. In particular, we demonstrate how this technique can be applied in the context of wireless mesh networks to support link switching or handover in the event of predicted link degradation or failure. The proposed technique has also been implemented and evaluated in a real-time experimental testbed. The results show that OU-LPT technique can significantly enhance the reliability of wireless links by reducing the rate of false triggers compared to a conventional linear prediction technique and therefore offers a new direction on how wireless link prediction, triggering and switching process can be conducted in the future.     

Thermal performances of enhanced smooth and spiky twisted tapes for laminar and turbulent tubular flows

This experimental study investigates the heat transfer properties over developing and developed flow regimes, the pressure drop coefficients and the thermal performance factors (TPF) of tubular flows with the continuous and spiky twist tapes enhanced by perforated, jagged and notched winglets. The axial distributions of Nusselt number (Nu) and the mean Fanning friction factors (f) of the tubular flows at Reynolds numbers (Re) ranging from 500 to 40000 are comparatively examined for five different types of twisted tapes with three twist ratios (y) of 1.875, 2.186 and 2.815 for each type of twisted tapes. Through this comparative study, the favorable types of twisted tapes which generate the higher degrees of HTE impacts over the developing and developed flow regimes are respectively identified. These newly devised twist tapes enrich the varieties of passive heat transfer enhancement (HTE) devices, especially for retrofit applications. A set of selective Nu and f results illustrates the thermal characteristics of the enhanced tubular flows by these twisted tapes. The HTE and TPF properties for all the present types of twisted tapes are subsequently compared with those reported for other types of twisted tapes in the literature. Among these comparative groups, the present V-notched spiky twisted tape generally offers the highest HTE impacts with favorable TPF performances. Empirical correlations that evaluate the averaged Nu over the developing and developed flow regimes; as well as and tube-wise averaged f for the enhanced tubular flows fitted with all the present types of twisted tapes are generated.