Effect of nitrogen on the antibacterial behavior of oxynitride glasses

The main drawback of bioglasses is their restricted use in load bearing applications and the consequent need to develop stronger glassy materials. This has led to the consideration of oxynitride glasses for numerous biomedical applications. This paper investigated two different types of glasses at a constant cationic ratio, with and without nitrogen (a N containing and a N-free glass composition) to better understand the effect of N on the biological properties of glasses. The results revealed that the addition of N increased the glass transition temperature, isoelectric point (IEP) and slightly increased wettability. Moreover, compared to N including glass, N-free glass exhibited better anti-bacterial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), two key bacteria that infect implants. In summary, these in vitro results indicated that amine functional groups existing in N containing glasses which are missing in N-free glasses, caused a slight difference in wetting behavior and a more obvious change in isoelectric point and in bacterial response. N-free glasses exhibited better inhibitory results both against E. coli and S. aureus compared to N including glass suggesting that oxygen rich glasses should be further studied for their novel antibacterial properties.     

Prolymphocytic leukemia: diagnosis and treatment. A case report

A patient with B-cell prolymphocytic leukemia (PLL) who has had a prolonged survival is presented. The patient was diagnosed incidentally while asymptomatic, but later developed progressive disease. He was refractory to alkylating agents and fludarabine, but responded to treatment with cyclophosphamide, doxorubicin, vincristine, and prednisone. This patient's prolonged survival may be due partly to his diagnosis at an indolent phase, possibly representing the early phase of the natural course of the disease. Diagnosis, clinical course, and treatment options for PLL are discussed.     

Use of Warranties on Highway Projects: A Real Option Perspective

Since the introduction of warranty provisions in federal highway jobs, more and more state departments of transportation (DOTs) have considered the use of such provisions to protect their initial investment. This paper describes the pros and cons of warranty contracting in highway construction based on a survey of warranty practices in the United States. In particular, the need for state DOTs to buy a warranty for a well-built project is questioned. As an alternative, this paper introduces the warranty option, which gives the DOT the right to buy a warranty only if it becomes necessary at the end of construction. This option is exercised if the performance on site warrants it. This paper describes the mechanics of the warranty option and its advantages over the conventional warranty. A bid evaluation model is also developed for the warranty option approach.     

Subsurface Characterization at Ground Failure Sites in Adapazari, Turkey

Ground failure in Adapazari, Turkey during the 1999 Kocaeli earthquake was severe. Hundreds of structures settled, slid, tilted, and collapsed due in part to liquefaction and ground softening. Ground failure was more severe adjacent to and under buildings. The soils that led to severe building damage were generally low plasticity silts. In this paper, the results of a comprehensive investigation of the soils of Adapazari, which included cone penetration test (CPT) profiles followed by borings with standard penetration tests (SPTs) and soil index tests, are presented. The effects of subsurface conditions on the occurrence of ground failure and its resulting effect on building performance are explored through representative case histories. CPT- and SPT-based liquefaction triggering procedures adequately identified soils that liquefied if the clay-size criterion of the Chinese criteria was disregarded. The CPT was able to identify thin seams of loose liquefiable silt, and the SPT (with retrieved samples) allowed for reliable evaluation of the liquefaction susceptibility of fine-grained soils. A well-documented database of in situ and index testing is now available for incorporating in future CPT- and SPT-based liquefaction triggering correlations.     

Growth and Characterization of YbBCO Films on Textured Gd2O3 Buffer-Layered Ni Tapes: All Sol–Gel Process

YbBa₂Cu₃O_7?x (YbBCO) thick films were grown on buffered, cube-textured Nickel tapes by sol–gel dip-coating method. Yb-123 films were prepared using solutions of Yb, Ba, and Cu organometallic compounds. A solution-based Gd₂O₃ buffer layer was deposited by dip-coating process with excellent texture and uniformity. The texture development and surface morphology of the buffer-layer films were examined by X-ray diffraction, pole figures, and ESEM analysis. Microstructure and characterization of Yb-123 films were done by ESEM, EDS, and XRD analysis. T _c and J _c were conducted by four-wire measurement method     

A New Recycled Al–Si–Mg Alloy for Sustainable Structural Die Casting Applications

Metallurgical and Materials Transactions A - The use of secondary aluminum for structural components in the automotive industry is limited by the high Fe contents in recycled alloys which often...     

Maximization of total surface area of Pt-SnO<Subscript>2</Subscript>/Al<Subscript>2</Subscript>O<Subscript>3</Subscript> catalyst by the Taguchi method

The maximization of the total surface area of Pt-SnO₂/Al₂O₃ catalyst was studied by using the Taguchi method of experimental design. The catalysts were prepared by sol-gel method. The effects of HNO₃, H₂O and aluminum nitrate concentrations and the stirring rate on the total surface area were studied at three levels of each. L₉ orthogonal array leading nine experiments was used in the experimental design. The parameter levels that give maximum total surface area were determined and experimentally verified. In the range of conditions studied it was found that, medium levels of HNO₃ and H₂O concentration and lower levels of aluminum nitrate concentration and stirring rate maximize the total surface area.     

Unveiling the presence of mixed oxidation states of Europium in Li7+δEuxLa3−δZr2−δO12−δ garnet and its impact on the Li-ion conductivity

Recently, lanthanides have been employed by researchers to examine their impact on the structure and properties of Li₇La₃Zr₂O₁₂ (LLZO) garnets. In this regard, we developed Europium oxide (Eu₂O₃) doped LLZO (Li_7+δEu_xLa_3−δZr_2−δO_12−δ) solid electrolyte which demonstrates a cubic phase with the symmetry of Iad (No.230) at room temperature. In this investigation, different concentrations of Eu ranging from 0.1 to 0.6 atoms per formula unit (pfu) were doped into Li₇La₃Zr₂O₁₂ to evaluate the impact of Eu on the stability of the cubic phase and thereby the ionic conductivity. The results unveiled that upon doping Eu³⁺ ions, the Eu²⁺ state is also formed and is then self-doped into the structure in which Rietveld refinement coupled with XPS, EPR, and solid-state NMR suggests that Eu³⁺ ions most probably partially occupy Zr⁴⁺ (16a) site, the Eu²⁺ ions occupy La³⁺ (24d) site, and the Li⁺ ions occupy two different sites (24d and 96h). It was further found that such a site preference induces distortion at LaO₈ polyhedrons opening up the neck for Li-ions diffusion, thereby enhancing the ionic conductivity. Moreover, it was revealed that Li-ions probably hop from 96h to 24d and then to 96h site to generate the Li-ion movement. Overall, by introducing Eu ions into the LLZO structure, an enhanced bulk ionic conductivity of 0.30 × 10⁻³ S/cm at 298 K with a minimum electronic conductivity of 2.547 × 10⁻⁹ S/cm at 298 K was achieved.