Moral value transfer from regulatory fit: What feels right is right and what feels wrong is wrong.

People experience regulatory fit (E. T. Higgins, 2000) when the strategic manner of their goal pursuit suits their regulatory orientation, and this regulatory fit feels right. Fit violation feels wrong. Four studies tested the proposal that experiences of fit can transfer to moral evaluations. The authors examined transfer of feeling wrong from fit violation by having participants in a promotion or prevention focus recall transgressions of commission or omission (Studies 1 and 2). Both studies found that when the type of transgression was a fit violation, participants expressed more guilt. Studies 3 and 4 examined transfer of feeling right from regulatory fit. Participants evaluated conflict resolutions (Study 3) and public policies (Study 4) as more right when the means pursued had fit. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Einsatz von Soja- und Sonnenblumen-Extraktionsschrot und Sonnenblumensamen als Eiweißfuttermittel fü Milchkühe

Use of soybean and sunflower meal and sunflower seed as a protein source for milking cows. In a feeding trial with 37 cows of Brown Swiss the impact of 10% soybean meal (Soja), 16% sunflower meal (Soblex) and 30% sunflower seed (Soblsa) in the feeding stuff on dry matter intake, milk yield, milk ingredients and also on the conditions of milk fat was investigated. Soybean meal and sunflower meal are similar protein sources for cows. Sunflower seeds caused a lower dry matter intake, milk yield and content of milk protein, but showed positive effects on the consistency of butterfat. Butterfat of the sunflower seed group had a higher iodine value (p<0.01) and a higher content of trans fatty acids (p<0.01) than the Soja- and Soblex-groups and resembled the composition of butterfat in the grazing periode.     

An optimization study on unprogrammed cryopreservation of human CD34+ bone marrow cells and their subsequent storage in an -80 degrees C mechanical freezer

Forty-one patients for whose direct care at least one machine was used and 33 registered nurses from the same five non-critical care units as the patients and from one related unit, participated in a semistructured tape-recorded interview to identify the core categories of the human-machine interface in clinical nursing practice and the relationships between them. Constant comparative analysis was used to organize and process the data. Patients perceived the machines as neutral because of their view of health care and because nurses were the interface between them and the machines. Nurses perceived the machines as either positive or negative, depending on their effect on the nurses' professional competence and the extent to which they worked directly with them.     

Experiences with the parallelisation of Monte Carlo problems

Monte Carlo problems can be parallelized in a natural way. Therefore parallelisation of production codes can be performed quite easily provided the codes are written in FORTRAN and can be transferred to the parallel machine and this machine has a pseudo random number generator available. The MORSE code is a code which can be transferred. We have done this to the CRAY-2 and the 32 processor version of the TX2 which is a binary tree structured parallel machine based on INTEL 80286 processors. We are able to reach efficiencies up to 95 % for realistic problems. Thus the same throughput as on one processor on the CRAY-2 could be reached. First experiments on the INTEL i860 based TX3 indicate an additional gain of a factor 100. This will allow to reconsider the Monte Carlo method in both nuclear engineering and as a general numerical tool.     

Influence of defined milk products on the flavour of white coffee beverages using static headspace gas chromatography–mass spectrometry/olfactometry and sensory analysis

The influence of milk processing and ingredients on the sensory properties of white coffee beverages has, as yet, not been thoroughly investigated, so in this study analysed milk products processed in a defined manner were added to a standardized, fresh coffee beverage; the resulting odour, taste and retronasal odour perception were measured by intensity tests, and selected volatiles were analysed by static headspace gas chromatography/mass spectrometry. After adding pasteurized consumers’ milk, the effects of a different fat content (3.5 and 1.5%) and fat dispersion were studied. The milk with the lower fat content and with smaller fat globules, resulting from double homogenization (each 250/50 bar), induced a more intense coffee-related retronasal odour perception, whereas the milk-related impression was nearly the same. The addition of casein increased the creamy and milky retronasal odour perception and reduced the coffee-related taste and retronasal odour. These correlations may result in a custom-made development of milky coffee beverages controlled in their nasal and retronasal odour and taste by the defined processing of the milk component. With instrumental analysis it was observable that the effect of the addition of twice-homogenized, twice-pasteurized low-fat milk and of the addition of whole milk was similar. In both cases more volatiles were released from the beverage than with the addition of low-fat milk that was homogenized once. This is an unexpected result, because the whole milk has a higher fat content than the low-fat milk and therefore a greater retention of the flavour compounds was expected. Is it possible that the flavour compounds are not dissolved in fat and that interactions happen only with fat globule membrane constituents?     

Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage

The mutational pattern of IgVH and IgVL genes from synovial tissue B cell hybridomas (n = 8) of patients (n = 4) with rheumatoid arthritis (RA) was analysed, which had been produced by the electrofusion technique without prior in vitro stimulation. The molecular data were correlated with immunohistopathological data and parameters of local disease activity. The IgVH genes of the B cell hybridomas belonged to the VH3 family (DP42; DP47, n = 2; DP53), the VH1 family (DP75), the VH4 family (DP71) and the VH5 family (DP73); 7/7 IgVH genes showed somatic mutations, the R/S ratio (CDR) was > 3 in 4/7 IgVH genes and the mean R/S ratio of all IgVH genes was 9.3 (CDR) and 1.0 (FR), suggesting an antigen-dependent selection. The IgVL/lambda genes belonged to the Vlambda1 family (DPL2, DPL5, DPL8nf), the Vlambda2 family (DPL11, n = 2) and to the Vlambda6 family (IGLV6S1); 6/6 IgVL genes showed somatic mutations, the R/S ratio (CDR) was > 3 in 3/6 IgVL genes and the mean R/S ratio of all IgVL was 3.0 (CDR) and 2.3 (FR), suggesting an antigen-dependent selection. The synovial tissue exhibited germinal centres in the follicles (3/4), with the unique distribution of Ki-M4+ follicular dendritic cells and Ki-67+ proliferating cells and a dominance of IgA+ plasma cells (3/3). All patients were positive for RF in serum and exhibited severe local symptoms (swelling 4/4; warmth 4/4; effusion 2/4), whereas the hybridomas were negative for RF. Since B cell hybridomas showed hypermutation and affinity selection for IgVH and IgVL/lambda genes and the patients exhibited severe local symptoms with germinal centres in synovial tissue, this study indicates that an antigen-driven process is behind the B cell expansion in the synovial tissue of clinically affected joints. These mutated B hybridomas were negative for RF, thus suggesting that antigens different from RF are also involved in the local B cell expansion and in the chronic synovitis of RA.     

Median‐unbiased Estimation and Exact Inference Methods for First‐order Autoregressive Models with Conditional Heteroscedasticity of Unknown Form

Abstract. Consider the first‐order autoregressive model y_t = φy_t?1 + ?_t, t = 1,…, T, with arbitrary initial non‐zero value y₀. Assuming that the error terms ?_t are independently distributed according to median‐zero distributions [ Zieliński (1999) Journal of Time Series Analysis, Vol. 20, p. 477] shows that the estimator conjectured by Hurwicz (1950) Statistical Inference in Dynamic Economic Models. New York, NY: Wiley – the median of the consecutive ratios y_t/y_t?1– is an exactly median‐unbiased estimator of the autoregressive parameter φ. This paper shows that the Hurwicz estimator remains median‐unbiased under more general distributional assumptions, without assuming statistical independence. In particular, no restrictions are placed on the degree of heterogeneity and dependence of the conditional variance process. A computationally efficient method is also proposed to build exact confidence intervals for the autoregressive parameter which are valid in finite samples for any value of φ on the real line.     

Investigation of the retronasal flavour release during the consumption of coffee with additions of milk constituents by ‘Oral Breath Sampling’

The aim of this study was the investigation of the influence of milk proteins (casein and whey proteins) and milk fat on the release of flavour compounds from white coffee beverages in the oral cavity. For this reason a retronasal headspace technique for measurement of the after-flavour was adapted. A ‘Gas Sampler’ equipped with a mouthpiece was used as an ‘Oral Breath Sampler (OBS)’. Analyses were performed by gas chromatography with mass spectrometric detection. It was noticed that the sampling at different hours resulted in different standard deviations. The flavour release is more constant in the morning (Variation coefficient from 3% to 28%; median: 10%) than in the afternoon (7–52%; median: 23%). The relationships between flavour release and some salivary parameters like salivation rate, buffer capability and protein content were also studied. The ‘Oral Breath Sampling’ was considered to be a valuable sampling method for the analysis of the retronasal aroma release from coffee beverages.