Finnish general contracting in the USSR

When dealing with a Soviet client, tendering, scheduling, consideration of available resources, management responsibilities, start-up and hand-over must be approached from a slightly different angle than when dealing with Western clients. Aspects of project management from feasibility analysis to hand-over are described, based on the experience of a Finnish general contractor, Finn Stroi.     

Efficient prolog programming

This paper presents some basic programming strategies for Prolog programmers. The strategies are based on knowledge about the operational behaviour of the Warren Abstract Machine (WAM). The aim is to provide simple principles for making programs both faster and less space-consuming. The programming hints given are mostly local, i.e. only a single clause or procedure need be considered at a time.     

Exploring US Business Cycles with Bivariate Loops Using Penalized Spline Regression

The phrase business cycle is usually used for short term fluctuations in macroeconomic time series. In this paper we focus on the estimation of business cycles in a bivariate manner by fitting two series simultaneously. The underlying model is thereby nonparametric in that no functional form is prespecified but smoothness of the functions are assumed. The functions are then estimated using penalized spline estimation. The bivariate approach will allow to compare business cycles, check and compare phase lengths and visualize this in forms of loops in a bivariate way. Moreover, the focus is on separation of long and short phase fluctuation, where only the latter is the classical business cycle while the first is better known as Friedman or Goodwin cycle, respectively. Again, we use nonparametric models and fit the functional shape with penalized splines. For the separation of long and short phase components we employ an Akaike criterion.     

Biological Role of the Intercellular Transfer of Glycosylphosphatidylinositol-Anchored Proteins: Stimulation of Lipid and Glycogen Synthesis

Glycosylphosphatidylinositol-anchored proteins (GPI-APs), which are anchored at the outer leaflet of plasma membranes (PM) only by a carboxy-terminal GPI glycolipid, are known to fulfill multiple enzymic and receptor functions at the cell surface. Previous studies revealed that full-length GPI-APs with the complete GPI anchor attached can be released from and inserted into PMs in vitro. Moreover, full-length GPI-APs were recovered from serum, dependent on the age and metabolic state of rats and humans. Here, the possibility of intercellular control of metabolism by the intercellular transfer of GPI-APs was studied. Mutant K562 erythroleukemia (EL) cells, mannosamine-treated human adipocytes and methyl-ß-cyclodextrin-treated rat adipocytes as acceptor cells for GPI-APs, based on their impaired PM expression of GPI-APs, were incubated with full-length GPI-APs, prepared from rat adipocytes and embedded in micelle-like complexes, or with EL cells and human adipocytes with normal expression of GPI-APs as donor cells in transwell co-cultures. Increases in the amounts of full-length GPI-APs at the PM of acceptor cells as a measure of their transfer was assayed by chip-based sensing. Both experimental setups supported both the transfer and upregulation of glycogen (EL cells) and lipid (adipocytes) synthesis. These were all diminished by serum, serum GPI-specific phospholipase D, albumin, active bacterial PI-specific phospholipase C or depletion of total GPI-APs from the culture medium. Serum inhibition of both transfer and glycogen/lipid synthesis was counteracted by synthetic phosphoinositolglycans (PIGs), which closely resemble the structure of the GPI glycan core and caused dissociation of GPI-APs from serum proteins. Finally, large, heavily lipid-loaded donor and small, slightly lipid-loaded acceptor adipocytes were most effective in stimulating transfer and lipid synthesis. In conclusion, full-length GPI-APs can be transferred between adipocytes or between blood cells as well as between these cell types. Transfer and the resulting stimulation of lipid and glycogen synthesis, respectively, are downregulated by serum proteins and upregulated by PIGs. These findings argue for the (patho)physiological relevance of the intercellular transfer of GPI-APs in general and its role in the paracrine vs. endocrine (dys)regulation of metabolism, in particular. Moreover, they raise the possibility of the use of full-length GPI-APs as therapeutics for metabolic diseases.     

Pricing based adaptive scheduling method for bandwidth allocation

In this paper we present a packet scheduling method which guarantees bandwidth of the connection and optimizes revenue of the network service provider. A closed form formula for updating the adaptive weights of a packet scheduler is derived from a revenue-based optimization problem. The weight updating procedure is fast and independent on the assumption of the connections’ statistical behavior. The features of the algorithm are simulated and analyzed with and without a call admission control (CAC) mechanism. We also show in context with the CAC procedure a mechanism for guaranteeing a specified mean bandwidth for different service classes.     

Integrated Time-to-Digital Converters Based on Interpolation

The main features of two time-to-digital convertersbased on interpolation are presented, together with some measurementresults. The first converter is based on digital delay line interpolatorsand has been implemented in a 1.2 µm CMOS process.It has a single-shot resolution of 1 ns (-value)and a nonlinearity less than ±50 ps in the measurementrange 5 to 500 ns. The power consumption of the circuit is 15mW. The second time digitizer has analog interpolators basedon time-to-voltage conversion and has been implemented in a 1.2 µm BiCMOS process. It has a single-shot resolutionof 50 ps and a nonlinearity less than 150 ps in the measurementrange 1 to 300 ns. The power consumption of this circuit is 200mW.     

Comparison of Two Integrated BiCMOS 950 MHz Direct I/Q Modulators

Two integrated direct I/Q modulators suitable for directupconversion with an output frequency of 950 MHz and baseband frequencies of60 to 500 kHz are fabricated in a 1.2 µm and 0.8 µm BiCMOSprocess, respectively, and their performance under various operatingconditions is discussed. The modulators use different phase shiftertopologies, one of which is based on digital CML latches and the other ondifferential pairs with resistive and capacitive emitter degeneration. Bothcircuits are operated using a single 5 V supply and they consume 50 mA or115 mA depending on the topology. The main properties of the CML modulatorare, for example, an output power of –11 ± 0.5 dBm at 100 MHzand –15 ± 2.25 dBm at 950 MHz over the temperature range of–10 to +85°C, LO suppression of 38 dBc and image rejection of41 dBc.     

Au@Hg Nanoalloy Formation Through Direct Amalgamation: Structural,Spectroscopic, and Computational Evidence for Slow Nanoscale Diffusion

Dynamic core–shell nanoparticles have received increasing attention in recent years. This paper presents a detailed study of Au–Hg nanoalloys, whose composing elements show a large difference in cohesive energy. A simple method to prepare Au@Hg particles with precise control over the composition up to 15 atom% mercury is introduced, based on reacting a citrate stabilized gold sol with elemental mercury. Transmission electron microscopy shows an increase of particle size with increasing mercury content and, together with X‐ray powder diffraction, points towards the presence of a core–shell structure with a gold core surrounded by an Au–Hg solid solution layer. The amalgamation process is described by pseudo‐zero‐order reaction kinetics, which indicates slow dissolution of mercury in water as the rate determining step, followed by fast scavenging by nanoparticles in solution. Once adsorbed at the surface, slow diffusion of Hg into the particle lattice occurs, to a depth of ca. 3 nm, independent of Hg concentration. Discrete dipole approximation calculations relate the UV–vis spectra to the microscopic details of the nanoalloy structure. Segregation energies and metal distribution in the nanoalloys were modeled by density functional theory calculations. The results indicate slow metal interdiffusion at the nanoscale, which has important implications for synthetic methods aimed at core–shell particles.