全文获取类型
收费全文 | 15543篇 |
免费 | 1624篇 |
国内免费 | 1170篇 |
专业分类
电工技术 | 1044篇 |
综合类 | 1410篇 |
化学工业 | 2261篇 |
金属工艺 | 1207篇 |
机械仪表 | 1109篇 |
建筑科学 | 1276篇 |
矿业工程 | 631篇 |
能源动力 | 460篇 |
轻工业 | 1345篇 |
水利工程 | 478篇 |
石油天然气 | 675篇 |
武器工业 | 226篇 |
无线电 | 1589篇 |
一般工业技术 | 1560篇 |
冶金工业 | 707篇 |
原子能技术 | 212篇 |
自动化技术 | 2147篇 |
出版年
2024年 | 61篇 |
2023年 | 251篇 |
2022年 | 553篇 |
2021年 | 760篇 |
2020年 | 514篇 |
2019年 | 370篇 |
2018年 | 386篇 |
2017年 | 452篇 |
2016年 | 393篇 |
2015年 | 615篇 |
2014年 | 835篇 |
2013年 | 993篇 |
2012年 | 1213篇 |
2011年 | 1206篇 |
2010年 | 1167篇 |
2009年 | 1060篇 |
2008年 | 1037篇 |
2007年 | 1083篇 |
2006年 | 960篇 |
2005年 | 802篇 |
2004年 | 617篇 |
2003年 | 523篇 |
2002年 | 580篇 |
2001年 | 546篇 |
2000年 | 380篇 |
1999年 | 274篇 |
1998年 | 129篇 |
1997年 | 117篇 |
1996年 | 88篇 |
1995年 | 87篇 |
1994年 | 47篇 |
1993年 | 52篇 |
1992年 | 35篇 |
1991年 | 25篇 |
1990年 | 16篇 |
1989年 | 30篇 |
1988年 | 16篇 |
1987年 | 11篇 |
1986年 | 11篇 |
1985年 | 4篇 |
1984年 | 3篇 |
1983年 | 4篇 |
1982年 | 6篇 |
1981年 | 6篇 |
1980年 | 5篇 |
1979年 | 7篇 |
1976年 | 2篇 |
1973年 | 1篇 |
1959年 | 1篇 |
1951年 | 2篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
美军将网络空间视为继陆、海、空、天外的第五大作战域,并将其列为国防部11项现代化优先事项之一,在美国等军事大国推动下,网络空间成为国家安全竞争和军事斗争的新疆域.文中对近年美国联邦政府、各部门及各军种发布的网络空间领域主要战略政策、规划计划进行梳理,研究其主要战略思想;分析美军2022财年国防预算、研究经费投向投量及重点项目的 研发情况.形成的研究成果将对我国网络空间安全领域研究提供技术支撑. 相似文献
2.
The capture of particles by charged droplets was simulated by considering the electrostatic interactions of droplet-droplet and droplet-particle. The results indicate that the electrostatic repulsion between droplets leads to a dynamic accumulation mode of particles. However, the droplet spacing has an insignificant effect on the capture efficiency when the electrostatic deposition predominates. The increase of droplet charge remarkably improves the capture efficiency, in which the capture of fine particles accounts for the largest proportion. Compared to the droplet charge, the droplet size shows a limited improvement in the capture efficiency. Reducing the droplet velocity prolongs the capture time instead of enhancing the capture capacity per unit time, thereby improving capture efficiency. 相似文献
3.
Rachana R. Borkute Sren Woelke Gang Pei Anca Dorhoi 《International journal of molecular sciences》2021,22(9)
Neutrophils readily infiltrate infection foci, phagocytose and usually destroy microbes. In tuberculosis (TB), a chronic pulmonary infection caused by Mycobacterium tuberculosis (Mtb), neutrophils harbor bacilli, are abundant in tissue lesions, and their abundances in blood correlate with poor disease outcomes in patients. The biology of these innate immune cells in TB is complex. Neutrophils have been assigned host-beneficial as well as deleterious roles. The short lifespan of neutrophils purified from blood poses challenges to cell biology studies, leaving intracellular biological processes and the precise consequences of Mtb–neutrophil interactions ill-defined. The phenotypic heterogeneity of neutrophils, and their propensity to engage in cellular cross-talk and to exert various functions during homeostasis and disease, have recently been reported, and such observations are newly emerging in TB. Here, we review the interactions of neutrophils with Mtb, including subcellular events and cell fate upon infection, and summarize the cross-talks between neutrophils and lung-residing and -recruited cells. We highlight the roles of neutrophils in TB pathophysiology, discussing recent findings from distinct models of pulmonary TB, and emphasize technical advances that could facilitate the discovery of novel neutrophil-related disease mechanisms and enrich our knowledge of TB pathogenesis. 相似文献
4.
Jasmin Kuhn Philipp M. Klein Nader Al Danaf Joel Z. Nordin Sren Reinhard Dominik M. Loy Miriam Hhn Samir El Andaloussi Don C. Lamb Ernst Wagner Yoshitsugu Aoki Taavi Lehto Ulrich Lchelt 《Advanced functional materials》2019,29(48)
Phosphorodiamidate morpholino oligomers (PMOs) are oligonucleotide analogs that can be used for therapeutic modulation of pre‐mRNA splicing. Similar to other classes of nucleic acid‐based therapeutics, PMOs require delivery systems for efficient transport to the intracellular target sites. Here, artificial peptides based on the oligo(ethylenamino) acid succinyl‐tetraethylenpentamine (Stp), hydrophobic modifications, and an azide group are presented, which are used for strain‐promoted azide‐alkyne cycloaddition conjugation with splice‐switching PMOs. By systematically varying the lead structure and formulation, it is determined that the type of contained fatty acid and supramolecular assembly have a critical impact on the delivery efficacy. A compound containing linolenic acid with three cis double bonds exhibits the highest splice‐switching activity and significantly increases functional protein expression in pLuc/705 reporter cells in vitro and after local administration in vivo. Structural and mechanistic studies reveal that the lipopeptide PMO conjugates form nanoparticles, which accelerate cellular uptake and that the content of unsaturated fatty acids enhances endosomal escape. In an in vitro Duchenne muscular dystrophy exon skipping model using H2K‐mdx52 dystrophic skeletal myotubes, the highly potent PMO conjugates mediate significant splice‐switching at very low nanomolar concentrations. The presented aminoethylene‐lipopeptides are thus a promising platform for the generation of PMO‐therapeutics with a favorable activity/toxicity profile. 相似文献
6.
地质特征认识对煤层气开发效果起着重要作用。在资源特征相差不大的情况下,发现煤层气相邻井的产量差异仍较大。排除工程因素后,通过选取8类地质参数,细致比对了保德区块低产井与邻井的参数特征,筛查出其关键因素为煤层微幅构造与顶板封盖条件,其中以微幅构造为主。据此,重新认识并划分出区块新的次生褶皱背斜单元、向斜单元和斜坡单元,获得了不同次生褶皱构造单元的开发特征。结果表明,高、低产井分布与次生褶皱背斜、向斜相关性高达92%。其中:高产井主要分布在次生褶皱背斜变化较缓、呈隆起状的“平台”,且煤层顶板以泥岩、碳质泥岩为主,封盖性较好;低产井主要分布在次生褶皱向斜,同一井台各井开发效果差异表现为从向斜条带轴部—向斜条带内—向斜条带外的煤层气井平均单井产量不断增加,到向斜轴部的距离大于向斜曲率半径73.5%的范围为主力产气区,小于向斜曲率半径40.0%范围为产水主力区。这对煤层气新井部署、生产管理、开发调整等,具有一定的指导意义。 相似文献
7.
8.
9.
10.