全文获取类型
收费全文 | 345篇 |
免费 | 10篇 |
专业分类
电工技术 | 3篇 |
化学工业 | 57篇 |
金属工艺 | 4篇 |
机械仪表 | 9篇 |
建筑科学 | 5篇 |
矿业工程 | 1篇 |
能源动力 | 9篇 |
轻工业 | 26篇 |
水利工程 | 1篇 |
石油天然气 | 5篇 |
无线电 | 22篇 |
一般工业技术 | 51篇 |
冶金工业 | 139篇 |
原子能技术 | 1篇 |
自动化技术 | 22篇 |
出版年
2022年 | 2篇 |
2021年 | 3篇 |
2020年 | 3篇 |
2019年 | 11篇 |
2018年 | 8篇 |
2017年 | 4篇 |
2016年 | 3篇 |
2015年 | 3篇 |
2014年 | 6篇 |
2013年 | 9篇 |
2012年 | 10篇 |
2011年 | 14篇 |
2010年 | 7篇 |
2009年 | 16篇 |
2008年 | 22篇 |
2007年 | 9篇 |
2006年 | 7篇 |
2005年 | 8篇 |
2004年 | 8篇 |
2003年 | 4篇 |
2002年 | 8篇 |
2001年 | 4篇 |
2000年 | 5篇 |
1999年 | 14篇 |
1998年 | 35篇 |
1997年 | 21篇 |
1996年 | 24篇 |
1995年 | 4篇 |
1994年 | 9篇 |
1993年 | 12篇 |
1991年 | 3篇 |
1990年 | 3篇 |
1989年 | 3篇 |
1988年 | 5篇 |
1987年 | 3篇 |
1985年 | 4篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1982年 | 5篇 |
1981年 | 4篇 |
1980年 | 4篇 |
1979年 | 3篇 |
1978年 | 4篇 |
1977年 | 2篇 |
1976年 | 5篇 |
1975年 | 2篇 |
1974年 | 2篇 |
1973年 | 2篇 |
1970年 | 1篇 |
1922年 | 1篇 |
排序方式: 共有355条查询结果,搜索用时 15 毫秒
1.
Dr. Blijke S. Kroezen Gabriele Conti Benedetta Girardi Dr. Jonathan Cramer Dr. Xiaohua Jiang Dr. Said Rabbani Jennifer Müller Maja Kokot Enrico Luisoni Prof. Daniel Ricklin Dr. Oliver Schwardt Prof. Beat Ernst 《ChemMedChem》2020,15(18):1706-1719
Siglecs are members of the immunoglobulin gene family containing sialic acid binding N-terminal domains. Among them, Siglec-8 is expressed on various cell types of the immune system such as eosinophils, mast cells and weakly on basophils. Cross-linking of Siglec-8 with monoclonal antibodies triggers apoptosis in eosinophils and inhibits degranulation of mast cells, making Siglec-8 a promising target for the treatment of eosinophil- and mast cell-associated diseases such as asthma. The tetrasaccharide 6’-sulfo-sialyl Lewisx has been identified as a specific Siglec-8 ligand in glycan array screening. Here, we describe an extended study enlightening the pharmacophores of 6’-sulfo-sialyl Lewisx and the successful development of a high-affinity mimetic. Retaining the neuraminic acid core, the introduction of a carbocyclic mimetic of the Gal moiety and a sulfonamide substituent in the 9-position gave a 20-fold improved binding affinity. Finally, the residence time, which usually is the Achilles tendon of carbohydrate/lectin interactions, could be improved. 相似文献
2.
We create a business as usual scenario for office equipment electricity use from industry forecasts of equipment sales, surveys of equipment densities by building type, measured data on wattage and usage by equipment type and projected lifetimes for equipment. We then calculate electricity used by building type and equipment type for Energy Star and advanced scenarios and explore the sensitivity of these results to variations in key input parameters. According to our analysis, the Energy Star programme will save the US almost US$1 billion annually starting in the year 2000, with minimal expenditure of public funds. 相似文献
3.
4.
Mary Cramer 《电子设计应用》2007,(3):20-20,22
目前,低成本手机数量不断增多,市场份额越来越大,比高端手机更受欢迎。研究表明,未来三年,低成本手机市场还将持续增长,这将是无线产业最主要的发展趋势之一,已经并将继续为无线手机制造商、服务供应商及芯片设计商带来金融、市场、战略和技术领域的重大变革与挑战。 相似文献
5.
6.
John G. Cramer 《Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment》1996,370(2-3):516-520
We present a new “no-background” procedure, based on the maximum likelihood method, for fitting the space-time size parameters of the particle production region in ultra-relativistic heavy ion collisions. This procedure uses an approximation to avoid the necessity of constructing a mixed-event background before fitting the data. 相似文献
7.
8.
Two new electrophilic monomers, 7,8-di(alkoxycarbonyl)-7,8-dicyanoquinodimethanes, were prepared. These quinodimethanes exhibit moderate electron-acceptor abilities and are highly reactive toward spontaneous homopolymerization in solution as well as in the solid state. Quinodimethane homopolymers were also obtained from heterogeneous spontaneous solution polymerization in the presence of styrene, p-methoxystyrene and isobutyl vinyl ether. 相似文献
9.