Something completely different: Informatik und Sport

Ohne Zusammenfassung     

Stoichiometric dye-binding procedure for the determination of the reactive lysine content of soya bean protein

A new analytical method has been developed for the determination of the reactive lysine content of soya bean protein. The method is based on the reaction of the free basic groups of the protein with 1-phenylazo-2 naphthol-6,8 disulphonic acid. With regard to the stoichiometry of the procedure, it has been proved, contrary to earlier reports, that the basic amino acids, histidine, arginine and lysine, each combine with one mole of the dye. After acylation with propionic anhydride lysine alone loses its dye reactivity. The usefulness of the proposed method has been demonstrated by the determination of the reactive lysine content of several untreated, heat-treated and acid-treated soya bean samples. The results show that heat damage of about 5% in reactive lysine content can be measured in 1·5 h with good reproducibility.     

The OODB path-method generator (PMG) using access weights and precomputed access relevance

A path-method is used as a mechanism in object-oriented databases (OODBs) to retrieve or to update information relevant to one class that is not stored with that class but with some other class. A path-method is a method which traverses from one class through a chain of connections between classes and accesses information at another class. However, it is a difficult task for a casual user or even an application programmer to write path-methods to facilitate queries. This is because it might require comprehensive knowledge of many classes of the conceptual schema that are not directly involved in the query, and therefore may not even be included in a user's (incomplete) view about the contents of the database. We have developed a system, called path-method generator (PMG), which generates path-methods automatically according to a user's database-manipulating requests. The PMG offers the user one of the possible path-methods and the user verifies from his knowledge of the intended purpose of the request whether that path-method is the desired one. If the path method is rejected, then the user can utilize his now increased knowledge about the database to request (with additional parameters given) another offer from the PMG. The PMG is based on access weights attached to the connections between classes and precomputed access relevance between every pair of classes of the OODB. Specific rules for access weight assignment and algorithms for computing access relevance appeared in our previous papers [MGPF92, MGPF93, MGPF96]. In this paper, we present a variety of traversal algorithms based on access weights and precomputed access relevance. Experiments identify some of these algorithms as very successful in generating most desired path-methods. The PMG system utilizes these successful algorithms and is thus an efficient tool for aiding the user with the difficult task of querying and updating a large OODB. Received July 19, 1993 / Accepted May 16, 1997     

Rapid crack propagation and arrest in the dcb specimen—an improved numerical analysis

A two-dimensional linear elastodynamic analysis of crack initiation, fast crack propagation and crack arrest in the DCB specimen is presented. The analysis is performed using the previously developed SMF2D code in its generation mode. The experimentally measured crack tip motion, as well as the specimen's geometry and its material characteristics, serve as input to the simulation. The dynamic stress intensity factor, the dynamic energy release rate and the various distributions of energies are subsequently evaluated. The numerical results are found to be in very good agreement with analytical and experimental findings.     

Reduction of carbamylated albumin by extended hemodialysis

Introduction Among conventional hemodialysis (CHD) patients, carbamylated serum albumin (C‐Alb) correlates with urea and amino acid deficiencies and is associated with mortality. We postulated that reduction of C‐Alb by intensive HD may correlate with improvements in protein metabolism and cardiac function. Methods One‐year observational study of in‐center nocturnal extended hemodialysis (EHD) patients and CHD control subjects. Thirty‐three patients receiving 4‐hour CHD who converted to 8‐hour EHD were enrolled, along with 20 controls on CHD. Serum C‐Alb, biochemistries, and cardiac MRI parameters were measured before and after 12 months of EHD. Findings EHD was associated with reduction of C‐Alb (average EHD change ?3.20 mmol/mol [95% CI ?4.23, ?2.17] compared to +0.21 [95% CI ?1.11, 1.54] change in CHD controls, P < 0.001). EHD was also associated with increases in average essential amino acids (in standardized units) compared to CHD (+0.38 [0.08, 0.68 95%CI]) vs. ?0.12 [?0.50, 0.27, 95% CI], P = 0.047). Subjects who reduced C‐Alb more than 25% were found to have reduced left ventricular mass, increased urea reduction ratio, and increased serum albumin compared to nonresponders, and % change in C‐Alb significantly correlated with % change in left ventricular mass. Discussion EHD was associated with reduction of C‐Alb as compared to CHD, and reduction of C‐Alb by EHD correlates with reduction of urea. Additional studies are needed to test whether reduction of C‐Alb by EHD also correlates with improved clinical outcomes.     

Evaluation and application of a semantic network partition

Semantic networks (SNs) are excellent knowledge representation structures. However, large semantic networks are difficult to comprehend. To overcome this difficulty, several methods of partitioning have been developed that rely on different mixes of structural and semantic methods. However, little has appeared in the literature concerning the question whether a partition of a semantic network creates subnetworks that agree with human insight. We address this issue by presenting a comparison between the results of an algorithmic partitioning method and a partition created by a group of experts. Subsequently, we show how a network partition can be used to generate various partial views of a semantic network, which facilitate user orientation. Examples from the Unified Medical Language System (UMLS) SN are used to demonstrate partial views     

Computing access relevance for path-method generation in OODB and IM-OODB

A path-method (PM) is a mechanism to retrieve or to update information relevant to one class, in an object-oriented database (OODB), that is not stored with that class but with some other class. The PM traverses a chain of classes and connections that ends at the class where the required information is stored. However, it is a difficult task for a user to write PMs. This is because it might require comprehensive knowledge of many classes of the conceptual schema. But a typical user has often incomplete or even inconsistent knowledge of the schema. Currently we are developing a system, called Path-Method Generator (PMG), which generates PMs automatically according to a naive user's requests. One algorithm of PMG uses numerical access relevance between pairs of classes as a guide for the traversal of an OODB schema. In this paper we define the notion of access relevance to measure the significance of the (indirect) connection between any two classes in an OODB and present efficient algorithms to compute access relevance. The manual PM generation in an interoperable multi object-oriented database (IM-OODB) is even more difficult than for one OODB since a user has to be familiar with several OODBs. We use a hierarchical approach for developing efficient online algorithms for the computation of access relevances in an IM-OODB, based on precomputed access relevances for each autonomous OODB. In an IM-OODB the access relevances are used as a guide in generating PMs between the classes of different OODBs.     

High-performance liquid chromatographic determination of tramadol in human plasma

Tramadol has been determined in human plasma samples using a sensitive high-performance liquid chromatographic method. The plasma samples were extracted with tert.-butylmethyl ether in one-step liquid-liquid extraction (recovery 86%) and analyses of the extracts were performed on reversed-phase silica gel using ion-pair chromatography (verapamil as an internal standard) and fluorescence detection. The method was applied to the determination of tramadol levels in twelve healthy volunteers after oral administration of 100 mg of tramadol in capsules of Protradon and Tramal.     

Grid-connected vehicles as the core of future land-based transport systems

Grid-connected vehicles (GCVs)—e.g., electric trains, metros, trams, and trolley buses—are propelled by electric motors directly connected to remote power sources. Their low at-vehicle energy consumption and ability to use a wide range of renewable energy sources make them strong contenders for urban and interurban transport systems in an era of energy constraints that favours use of renewable fuels, which may lie ahead. Needs for autonomous motorised mobility could be acceptably met in large measure by deployment of personal GCVs, also known as personal rapid transit (PRT). Alternatives, including fuel-cell vehicles and dual-drive vehicles fuelled with ethanol, will be less feasible. The ‘car of the future’ may not be an automobile so much as a PRT element of a comprehensive GCV-based system that offers at least as much utility and convenience as today's transport systems.