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排序方式: 共有427条查询结果,搜索用时 15 毫秒
1.
Vanessa Modelski Schatkoski Thaís Larissa do Amaral Montanheiro Beatriz Rossi Canuto de Menezes Raissa Monteiro Pereira Karla Faquine Rodrigues Renata Guimarães Ribas Diego Morais da Silva Gilmar Patrocínio Thim 《Ceramics International》2021,47(3):2999-3012
Studies related to biomaterials that stimulate the repair of living tissue have increased considerably, improving the quality of many people's lives that require surgery due to traumatic accidents, bone diseases, bone defects, and reconstructions. Among these biomaterials, bioceramics and bioactive glasses (BGs) have proved to be suitable for coating materials, cement, scaffolds, and nanoparticles, once they present good biocompatibility and degradability, able to generate osteoconduction on the surrounding tissue. However, the role of biomaterials in hard tissue engineering is not restricted to a structural replacement or for guiding tissue regeneration. Nowadays, it is expected that biomaterials develop a multifunctional role when implanted, orchestrating the process of tissue regeneration and providing to the body the capacity to heal itself. In this way, the incorporation of specific metal ions in bioceramics and BGs structure, including magnesium, silver, strontium, lithium, copper, iron, zinc, cobalt, and manganese are currently receiving enhanced interest as biomaterials for biomedical applications. When an ion is incorporated into the bioceramic structure, a new category of material is created, which has several unique properties that overcome the disadvantages of primitive material and favors its use in different biomedical applications. The doping can enhance handling properties, angiogenic and osteogenic performance, and antimicrobial activity. Therefore, this review aims to summarize the effect of selected metal ion dopants into bioceramics and silicate-based BGs in bone tissue engineering. Furthermore, new applications for doped bioceramics and BGs are highlighted, including cancer treatment and drug delivery. 相似文献
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3.
The first Brazilian uranium mine and mill are located on the Poços de Caldas plateau, in the Central State of Minas Gerais. The pre-operational environmental survey was carried out over a period of two years by the Brazilian Nuclear Energy Commission (CNEN), through the Instituto de Radioproteção e Dosimetria (IRD). The selection of the materials to be monitored, the sampling points and the radionuclides to be analysed were based on critical parameters taking into account the meteorological and hydrological characteristics of the site as well as land use. The results obtained are sufficient to characterize the environmental background of the area, and will allow an assessment of the environmental impact due to the operation of the facility and an evaluation of the adequacy of the effluent emmission control measures. In relation to their contribution to the population dose, the results indicated that 226Ra and 210Pb will be the important radionuclides. 相似文献
4.
Electrochemical studies were carried out with disk electrodes of Invar (Fe-36%Ni) in phosphate solution at pH 6.0, using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) techniques, comparing the results with those for low carbon steel and pure Ni. Invar shows a reduced corrosion when compared to carbon steel in the weakly inhibitive solution though inferior to pure Ni. Phosphate anion is responsible for the formation of a protecting and stable film on the alloy surface at pH 6.0.Cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) with Invar disk electrodes (Fe-36%Ni) in phosphate solutions at pH=6.0 were carried out. Results were compared with those of carbon steel and pure Ni. 相似文献
5.
We present a computational study of parametric tabu search for solving 0–1 mixed integer programming (MIP) problems, a generic heuristic for general MIP problems proposed by Glover [Glover F. Parametric tabu-search for mixed integer programs. Computers and Operations Research 2006; 33: 2449–94.]. This approach solves a series of linear programming problems by incorporating branching inequalities as weighted terms in the objective function. New strategies are proposed for uncovering feasible and high-quality solutions and extensive computational tests are performed on instances from the literature. 相似文献
6.
In the last few decades the continuous monitoring of complex dynamic systems has become an increasingly important issue across diverse engineering areas. This paper presents a pattern recognition based system that uses visual-based efficient invariants features for continuous monitoring of induction motors. The procedures presented here are based on the image identification of the 3-D current state space patterns that allow the identification of distinct fault types and, furthermore, their corresponding severity. This automatic fault detection system deals with time-variant electric currents and is based on the identification of three-phase stator currents specified patterns. Several simulation and experimental results are also presented in order to verify the effectiveness of the proposed methodology. 相似文献
7.
Jun Okamoto Jr. Valdir Grassi Jr. Paulo Faria Santos Amaral Benedito Geraldo Miglio Pinto Daniel Pipa Gustavo Pinto Pires Marcus Vinicius Maciel Martins 《Journal of Intelligent and Robotic Systems》2012,66(1-2):23-35
Inspection for corrosion of gas storage spheres at the welding seam lines must be done periodically. Until now this inspection is being done manually and has a high cost associated to it and a high risk of inspection personel injuries. The Brazilian Petroleum Company, Petrobras, is seeking cost reduction and personel safety by the use of autonomous robot technology. This paper presents the development of a robot capable of autonomously follow a welding line and transporting corrosion measurement sensors. The robot uses a pair of sensors each composed of a laser source and a video camera that allows the estimation of the center of the welding line. The mechanical robot uses four magnetic wheels to adhere to the sphere’s surface and was constructed in a way that always three wheels are in contact with the sphere’s metallic surface which guarantees enough magnetic atraction to hold the robot in the sphere’s surface all the time. Additionally, an independently actuated table for attaching the corrosion inspection sensors was included for small position corrections. Tests were conducted at the laboratory and in a real sphere showing the validity of the proposed approach and implementation. 相似文献
8.
Kyriazis G.A. de Campos M.L.R. 《IEEE transactions on instrumentation and measurement》2005,54(2):496-499
A digital sampling algorithm that uses two high-resolution integrating voltmeters in a master-slave configuration for accurately measuring the harmonic magnitudes and phase angles of two low-noise, low-frequency, arbitrary voltage signals is presented. It is shown that it is possible to measure up to 64 harmonic magnitudes of 60-Hz signals with an uncertainty of less than 13 /spl mu/V/V relative to the fundamental using commercial stable signal generators and high-resolution digital voltmeters. It is also possible to measure the phase shift between the fundamental components of two equally-synthesized 60-Hz signals with about 3.8% total harmonic distortion with an uncertainty of less than 2.5 /spl mu/rad. Even lower uncertainties can be obtained for low-distortion signals. The algorithm was applied to the measurement of the harmonics of periodic arbitrary signals generated by a commercial source. The differences between computed and measured values of harmonic magnitude suggest that stable digitally-synthesized signal generators can be used as calculable standards of harmonic distortion with an accuracy of less than 6 parts in 10/sup 5/ relative to the fundamental. 相似文献
9.
Felipe Girotto Campos Diana Pacheco Seixas Gustavo Ribeiro Barzotto Letícia Galhardo Jorge Karina Renostro Ducatti Gisela Ferreira Tatiane Maria Rodrigues Edvaldo Aparecido Amaral da Silva Carmen Sílvia Fernandes Boaro 《International journal of molecular sciences》2022,23(21)
A momentary increase in cytoplasmic Ca2+ generates an oscillation responsible for the activation of proteins, such as calmodulin and kinases, which interact with reactive oxygen species (ROS) for the transmission of a stress signal. This study investigated the influence of variations in calcium concentrations on plant defense signaling and photosynthetic acclimatization after mechanical damage. Solanum lycopersicum Micro-Tom was grown with 0, 2 and 4 mM Ca2+, with and without mechanical damage. The expression of stress genes was evaluated, along with levels of antioxidant enzymes, hydrogen peroxide, lipid peroxidation, histochemistry, photosynthesis and dry mass of organs. The ROS production generated by mechanical damage was further enhanced by calcium-free conditions due to the inactivation of the oxygen evolution complex, contributing to an increase in reactive species. The results indicated that ROS affected mechanical damage signaling because calcium-free plants exhibited high levels of H2O2 and enhanced expression of kinase and RBOH1 genes, necessary conditions for an efficient response to stress. We conclude that the plants without calcium supply recognized mechanical damage but did not survive. The highest expression of the RBOH1 gene and the accumulation of H2O2 in these plants signaled cell death. Plants grown in the presence of calcium showed higher expression of SlCaM2 and control of H2O2 concentration, thus overcoming the stress caused by mechanical damage, with photosynthetic acclimatization and without damage to dry mass production. 相似文献
10.
Srgio R. S. Veloso Raquel G. D. Andrade Valria Gomes Carlos O. Amorim Vítor S. Amaral Vernica Salgueirio Paulo J. G. Coutinho Paula M. T. Ferreira Miguel A. Correa-Duarte Elisabete M. S. Castanheira 《International journal of molecular sciences》2022,23(22)
Superparamagnetic nanoparticles are of high interest for therapeutic applications. In this work, nanoparticles of calcium-doped manganese ferrites (CaxMn1−xFe2O4) functionalized with citrate were synthesized through thermally assisted oxidative precipitation in aqueous media. The method provided well dispersed aqueous suspensions of nanoparticles through a one-pot synthesis, in which the temperature and Ca/Mn ratio were found to influence the particles microstructure and morphology. Consequently, changes were obtained in the optical and magnetic properties that were studied through UV-Vis absorption and SQUID, respectively. XRD and Raman spectroscopy studies were carried out to assess the microstructural changes associated with stoichiometry of the particles, and the stability in physiological pH was studied through DLS. The nanoparticles displayed high values of magnetization and heating efficiency for several alternating magnetic field conditions, compatible with biological applications. Hereby, the employed method provides a promising strategy for the development of particles with adequate properties for magnetic hyperthermia applications, such as drug delivery and cancer therapy. 相似文献