Hybrid materials based on metal oxides and poly(organophosphazenes)

In this paper the sol-gel preparation of hybrid materials made of metal oxide and polytorganophosphazenel components is described. The main problem focused on during this research was to avoid phase separation in order to get homogeneous materials. This problem was pursued looking at the formation of genuine chemical bonds between the exploited polyphosphazenes and the inorganic composite networks. Investigations on the thermal, mechanical, and electroconductive properties of the synthesized, phosphazene-containing composite materials showed that these matrices presented improved mechanical and thermal features with respect to those of the original phosphazene macromolecule, while the ionic conductivities of the prepared molecular hybrids doped with lithium or silver trillate are of the same order of magnitude as those measured for the neat, original phosphazene substrate.Presented at the Ist Italian Workshop on Cyclo- and Polytphosphazenel Materials. February 15–16, 1996. at the CNR Research Area in Padova, Italy.     

A new adaptive mean frequency estimator: application to constant variance color flow mapping

A class of adapted mean frequency estimators is proposed for color flow mapping. These estimators can be fitted to the specific characteristics of a given Doppler signal to optimize the compromise between the range of analysable frequencies and the variance of mean frequency estimation. A sub-optimal estimator is derived for real-time applications, and an adaptive criterion based on the Doppler signal variance is developed for color flow mapping applications. Its performance is compared to that of the usual correlation phase estimator on simulated Doppler signals and on synthetic Doppler images. An improvement in image quality is achieved, mainly for low signal-to-noise ratio Doppler signals.     

Multimode equivalent network representation for junctions between coaxial and circular waveguides

In this article we present two contributions to the study of coaxial waveguide structures. First, we present an efficient and accurate technique to evaluate the modes in the coaxial waveguides; second, we analyze junctions involving coaxial and circular waveguides using the multimode equivalent network representation. Numerical and experimental results are presented, showing good agreement. © 1997 John Wiley & Sons, Inc. Int J Microwave Millimeter-Wave CAE 7: 180–194, 1997.     

On structuring proof search for first order linear logic

Full first-order linear logic can be presented as an abstract logic programming language in Miller's system Forum, which yields a sensible operational interpretation in the ‘proof search as computation’ paradigm. However, Forum still has to deal with syntactic details that would normally be ignored by a reasonable operational semantics. In this respect, Forum improves on Gentzen systems for linear logic by restricting the language and the form of inference rules. We further improve on Forum by restricting the class of formulae allowed, in a system we call G-Forum, which is still equivalent to full first-order linear logic. The only formulae allowed in G-Forum have the same shape as Forum sequents: the restriction does not diminish expressiveness and makes G-Forum amenable to proof theoretic analysis. G-Forum consists of two (big) inference rules, for which we show a cut elimination procedure. This does not need to appeal to finer detail in formulae and sequents than is provided by G-Forum, thus successfully testing the internal symmetries of our system.     

Time to relapse has prognostic value in patients with aggressive lymphoma enrolled onto the Parma trial

PURPOSE: The purpose of this study was to investigate the prognostic value of time to relapse in 188 adult patients with intermediate- or high-grade non-Hodgkin's lymphoma (NHL) included on the Parma trial at the time of their first relapse. PATIENTS AND METHODS: The median follow-up of these patients is 102 months after registration onto the Parma study. Time to relapse was calculated from initial diagnosis, and a cutoff of 12 months was used to separate 77 patients defined as early relapse from 111 patients defined as late relapse. RESULTS: Patients with early and late relapses had significantly different overall response rates to salvage therapy with two courses of dexamethasone, high-dose cytarabine, and cisplatin (DHAP; 40% v 69%; P=.00007) and different 8-year survival rates (13% v 29%; P=.00001). Features at relapse with a negative prognostic value in univariate analysis were higher than normal lactic dehydrogenase (LDH) levels, tumor size greater than 5 cm, Ann Arbor stages III to IV, and Karnofsky score less than 80%. Therefore, multivariate analyses were performed. Time to relapse (P=.001) and LDH levels at relapse (P=.003) had independent prognostic value, whereas tumor size did not reach statistical significance in the logistic model that predicted overall response after two courses of DHAP. The study of prognostic factors for overall survival (OS) and progression-free survival (PFS) confirmed the prognostic value of time to relapse (P < .0001 for OS and P=.005 for PFS) independent of response or treatment after two courses of DHAP. CONCLUSION: Time to relapse may be used to stratify patients at time of first relapse of intermediate to high-grade non-Hodgkin's lymphoma.     

Multimode equivalent network representation for the scattering frommultistrip gratings

A multimode equivalent network representation (MEN) is proposed for the scattering from a multistrip grating. Previously, rigorous analytical results were developed involving gratings with one or two strips in a period. In the present paper, the MEN representation is extended to planar gratings with an arbitrary number of strips or apertures per unit cell. Both TE and TM incidence are described. The extension is obtained combining the MEN formulation with the method of moments solution (MoM) of the relevant integral equation. The code thus obtained retains the key feature of the MEN representation, namely the frequency independence of the characterization, and is much more flexible than the analytical solutions previously derived. The MoM solution procedure is described in detail and several application examples are discussed     

Two‐dimensional fluorescence as a fingerprinting tool for monitoring wastewater treatment systems

BACKGROUND: The use of two‐dimensional (2D) fluorescence for monitoring complex biological systems requires careful assessment of the effect of chemical species present, which may be fluorescent and/or may interfere with the fluorescence response of target fluorophores. Given the complexity of fluorescence data (excitation emission matrices—EEMs), the challenge is how to recover the information embedded into those EEMs that can be related quantitatively with the observed performance of the biological processes under study. RESULTS: This work shows clearly that interference effects (such as quenching and inner filter effects) occur due to the presence of multiple species in complex biological media, such as natural water matrices, wastewaters and activated sludge. A statistical multivariate analysis is proposed to recover quantitative information from 2D fluorescence data, correlating EEMs with the observed performance. A selected case study is discussed, where 2D fluorescence spectra obtained from the effluent of a membrane bioreactor were compressed using PARAFAC and successfully correlated with the effluent chemical oxygen demand, using projection to latent structures modelling. CONCLUSION: This study demonstrates the potential of using 2D fluorescence spectroscopy as a status fingerprint. Additionally, it is shown how statistical multivariate data analysis can be used to correlate EEMs with selected performance parameters for monitoring of biological systems. Copyright © 2011 Society of Chemical Industry     

Mesoscale characterization of coupled hydromechanical behavior of a fractured-porous slope in response to free water-surface movement

To better understand the role of groundwater-level changes on rock-slope deformation and damage, a carbonate rock slope (30 m×30 m×15 m) was extensively instrumented for mesoscale hydraulic and mechanical measurements during water-level changes. The slope is naturally drained by a spring that can be artificially closed or opened by a water gate. In this study, a 2-h slope-dewatering experiment was analyzed. Changes in fluid pressure and deformation were simultaneously monitored, both at discontinuities and in the intact rock, using short-base extensometers and pressure gauges as well as tiltmeters fixed at the slope surface. Field data were analyzed with different coupled hydromechanical (HM) codes (ROCMAS, FLAC^3D, and UDEC).

Field data indicate that, in the faults, a 40 kPa pressure fall occurs in 2 min and induces a 0.5–31×10⁻⁶ m normal closure. Pressure fall is slower in the bedding-planes, lasting 120 min, with no normal deformation. No pressure change or deformation is observed in the intact rock. The slope surface displays a complex tilt towards the interior of the slope, with magnitudes ranging from 0.6 to 15×10⁻⁶ rad.

Close agreement with model for both slope surface and internal measurements is obtained when a high variability in slope-element properties is introduced into the models, with normal stiffnesses of k_{n_faults}=10⁻³×k_{n_bedding-planes} and permeabilities of k_{h_faults}=10³×k_{h_bedding-planes}. A nonlinear correlation between hydraulic and mechanical discontinuity properties is proposed and related to discontinuity damage. A parametric study shows that 90% of slope deformation depends on HM effects in a few highly permeable and highly deformable discontinuities located in the basal, saturated part of the slope while the remaining 10% is related to elasto-plastic deformations in the low-permeability discontinuities induced by complex stress/strain transfers from the high-permeability zones. The periodicity and magnitude of free water-surface movements cause 10–20% variations in those local stress/strain accumulations related to the contrasting HM behavior for high- and low-permeability elements of the slope. Finally, surface-tilt monitoring coupled with internal localized pressure/deformation measurements appears to be a promising method for characterizing the HM properties and behavior of a slope, and for detecting its progressive destabilization.