排序方式: 共有41条查询结果,搜索用时 78 毫秒
1.
F. Morichetti A. Melloni 《Photonics Technology Letters, IEEE》2006,18(8):923-925
In this letter, novel devices based on ring-resonator phase-shifters are proposed for the realization of efficient polarization converters with periodical spectral response. The main spectral properties of several architectures, including parallel-coupled and directly coupled ring-resonators, are analytically investigated and conditions for complete polarization rotation are derived. The exploitation as polarization interleavers and polarization splitters/combiners is also briefly discussed. 相似文献
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Repeated high dose (5.0 mg/kg) anabolic-androgenic steroid (AAS) exposure during adolescence stimulates offensive aggression in male Syrian hamsters. These studies examined whether AAS-induced aggression was regulated by the activity of serotonin (5HT) type-1B receptors and correlated with altered 5HT1B expression. AAS-treated hamsters were tested for offensive aggression following the administration of the 5HT1B agonist anpirtoline (0.125-0.5 mg/kg). Anpirtoline dose-dependently reduced select components of the AAS-induced aggressive response, with significant reductions observed at 0.25 mg/kg. Aggressive, AAS-treated hamsters showed significant decreases in the area covered by 5HT1B-containing neuronal puncta and increases in the number of 5HT1B-containing neuronal somata in select brain regions implicated in aggression control. Together, these data support a role for site-specific alterations in 5HT1B signaling and expression in adolescent AAS-induced aggression. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
3.
Grimes Jill M.; Ricci Lesley A.; Melloni Richard H. Jr. 《Canadian Metallurgical Quarterly》2006,120(1):115
In hamsters, adolescent anabolic-androgenic steroid (AAS) exposure facilitates offensive aggression, in part by altering the development and activity of anterior hypothalamic arginine vasopressin (AH-AVP). This study assessed whether these effects were lasting by examining aggression and AH-AVP during AAS withdrawal. Adolescent hamsters administered AAS were tested as adults for aggression at 1, 4, 11, 18, or 25 days of withdrawal, sacrificed the following day, and examined for AH-AVP afferent innervation using immunohistochemistry. Through Day 12 of withdrawal, aggression and AVP were significantly higher in AAS-treated hamsters than in controls. These differences were no longer observable by Day 19 of withdrawal, at which point the behavior and neurobiology of AAS-treated hamsters reverted to that observed in controls. These data indicate that adolescent AAS exposure has short-term, reversible effects on both aggression and AH-AVP, correlating AH-AVP with the aggressive/nonaggressive behavioral phenotype during AAS withdrawal. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
4.
Grimes Jill M.; Ricci Lesley A.; Melloni Richard H. Jr. 《Canadian Metallurgical Quarterly》2007,121(5):941
In hamsters (Mesocricetus auratus), anabolic-androgenic steroid (AAS) exposure during adolescence facilitates offensive aggression that is correlated with the enhanced development of the arginine vasopressin (AVP) neural system and reduced development of the serotonin (5-HT) neural system in the anterior hypothalamus (AH). This study examined the temporal onset of these effects by measuring aggression and AH AVP and 5-HT during progressively shorter periods of AAS exposure during adolescent development. The authors tested adolescent hamsters that received AAS for 3, 7, 14, or 28 days for offensive aggression and then examined the hamsters for AVP/5-HT afferent innervation to the AH using immunohistochemistry. While reductions in AH 5-HT afferent innervation were detectable by 7 days of AAS exposure, no concomitant increases in offensive aggression were observed compared to oil-treated littermates. In contrast, by Day 14 of AAS treatment, AH AVP and offensive aggression were significantly higher than oil-treated controls. These data indicate that relatively short-term adolescent AAS exposure alters aggression and AH 5-HT and AVP development, yet only alterations in AH AVP development correlate with temporal onset of the aggressive behavioral phenotype during adolescent AAS exposure. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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A mode-matching technique for the analysis of TE011 mode waveguide cylindrical bandpass filters including losses is presented. The modes of a lossy radial waveguide are derived and the generalized scattering matrix of the lossy cavity coupled by two rectangular apertures is computed enforcing an impedance boundary condition on the cavity sidewall. Cavity sidewall losses as well as top and bottom wall losses are therefore taken accurately into account. Numerical and experimental results are given for a four cavity filter in Ka band 相似文献
7.
Memon Faisal Ahmed Morichetti Francesco Arain Zulfiqar Ali Korai Umair Ahmed Melloni Andrea 《Wireless Personal Communications》2019,106(4):2149-2161
Wireless Personal Communications - In this work, we first analyse the behaviour of semiconductor laser in the presence of weak-to-moderate feedback from a single (lumped) and double external cavity... 相似文献
8.
Nicola Peserico Rossella Castagna Laurent Bellieres Manuel Rodrigo Andrea Melloni 《IET nanobiotechnology / IET》2018,12(1):87
We present an approach to functionalise optical microring resonators as hybridisation platforms, using tip‐mould reactive microcontact printing process. Derived from reactive microcontact printing using an ad hoc mould of polydimethylsiloxane (PDMS), the method functionalises single microring resonator with a target‐specific capture agent. The authors report the functionalisation of silicon nitride (SiN) diameter microring resonator with single‐strand DNA and the hybridisation detection of 100 nM target analyte, while concurrently monitoring not‐functionalised microring as a control sensor. Results show that the functionalisation approach permits to address single microring resonators with mutual distance lower than with high precision, enabling a better integration of multiple spotting zones on the chip concerning traditional functionalisation procedures.Inspec keywords: DNA, molecular biophysics, biosensors, microsensors, optical resonators, microcavities, soft lithography, polymers, silicon compounds, integrated optics, optical sensors, micro‐opticsOther keywords: tip‐mould reactive microcontact printing, optical microring resonator, hybridisation platforms, polydimethylsiloxane, PDMS, target‐specific capture agent, single‐strand DNA, hybridisation detection, multiple spotting zones, chip, size 200 mum, SiN 相似文献
9.
E Melloni M Michetti F Salamino S Pontremoli 《Canadian Metallurgical Quarterly》1998,273(21):12827-12831
A natural calpain activator protein has been isolated from bovine brain and characterized in its properties and molecular structure. The protein is a homodimer with a molecular mass of about 30 kDa and results in being almost identical to UK114 goat liver protein. Significant similarities with mouse HR12 protein were also observed, whereas a lower degree of similarity was found with a family of heat-responsive proteins named YJGF and YABJ from Haemophilus influenzae and Bacillus subtilis, respectively. The brain activator expresses a strict specificity for the mu-calpain isoform, being completely ineffective on the m-calpain form. As expected, also UK114 was found to possess calpain-activating properties, indistinguishable from those of bovine brain activator. A protein showing the same calpain-activating activity has been also isolated from human red cells, indicating that this factor is widely expressed. All these activators are efficient on mu-calpain independently from the source of the proteinase. The high degree of specificity of the calpain activator for a single calpain isoform may be relevant for the understanding of sophisticated intracellular mechanisms underlying intracellular proteolysis. These data are indicating the existence of a new component of the Ca2+-dependent proteolytic system, constituted of members of a chaperonin-like protein family and capable of promoting intracellular calpain activation. 相似文献
10.
In golden hamsters, offensive aggression is facilitated by vasopressin and inhibited by serotonin. We tested whether these neurotransmitter systems respond to modifications resulting from the stress of threat and attack (i.e., social subjugation) during puberty. Male golden hamsters were weaned at postnatal day 25 (P25), exposed daily to aggressive adults from P28 to P42, and tested for offensive aggression as young adults (P45). The results showed a context-dependent alteration in aggressive behavior. Subjugated animals were more likely to attack younger and weaker intruders than nonsubjugated controls. Conversely, subjugated animals were less likely to attack animals of similar size and age. After testing, the animals were killed, and their brains were collected to determine whether these behavioral changes are underlined by changes in the vasopressin and serotonin systems. Social subjugation resulted in a 50% decrease in vasopressin levels within the anterior hypothalamus, a site involved in the regulation of aggression. Furthermore, whereas the density of vasopressin-immunoreactive fibers within the area was not significantly altered in subjugated animals, the number of serotonin-immunoreactive varicosities within the anterior hypothalamus and lateral septum was 20% higher in subjugated animals than in their controls. These results establish puberty as a developmental period sensitive to environmental stressors. Furthermore, the results show that changes in the vasopressin and serotonin systems can correlate with behavioral alterations, supporting the role of these two neurotransmitters in the regulation of aggression. 相似文献