Review: the latest advances in biomedical applications of chitosan hydrogel as a powerful natural structure with eye-catching biological properties

Journal of Materials Science - Chitosan is one of the natural cationic polymers with unique properties such as non-toxicity, biodegradability, biocompatibility, environmentally friendly that has...     

Low Temperature Characteristics of the Metal–Superconductor NIS Tunneling Thermometer

We discuss the temperature dependence of a common low temperature local thermometer, a tunnel junction between a superconductor and a normal metal (NIS junction). Towards the lowest temperatures its characteristics tend to saturate, which is usually attributed to selfheating effects. In this technical note, we reanalyze this saturation and show that the temperature independent subgap current of the junction alone explains in some cases the low temperature behavior quantitatively.

     

Expression of Main Toll-Like Receptors in Patients with Different Types of Colorectal Polyps and Their Relationship with Gut Microbiota

Abnormal activation of Toll-like receptor (TLRs) signaling can result in colon cancer development. The aim of this study was to investigate the expression of important TLRs in different histological types of colorectal polyps and evaluate their relationship with intestinal microbiota. The expression levels of TLR2, 3, 4, and 5 were analyzed in intestinal biopsy specimens of 21 hyperplastic polyp (HP), 16 sessile serrated adenoma (SSA), 29 tubular adenoma (TA), 21 villous/tubulovillous (VP/TVP) cases, and 31 normal controls. In addition, selected gut bacteria including Streptococcus bovis, Enterococcus faecalis, Enterotoxigenic Bacteroides fragilis (ETBF), Fusobacterium nucleatum, Porphyromonas spp., Lactobacillus spp., Roseburia spp., and Bifidobacterium spp. were quantified in fecal samples using absolute qRT PCR, and, finally, the association between TLRs and these gut microbiota- was evaluated by Spearman’s correlation coefficient. Higher expression of TLR2 and TLR4 in VP/TVP and TA, and lower expression levels of TLR3 and TLR5 in all type of polyps were observed. The differences in TLR expression patterns was not only dependent on the histology, location, size, and dysplasia grade of polyps but also related to the intestinal microbiota patterns. TLR2 and TLR4 expression was directly associated with the F. nucleatum, E. faecalis, S. bovis, Porphyromonas, and inversely to Bifidobacterium, Lactobacillus, and Roseburia quantity. Furthermore, TLR3 and TLR5 expression was directly associated with Bifidobacterium, Roseburia, and Lactobacillus quantity. Our results suggest a possible critical role of TLRs during colorectal polyp progression. An abnormal regulation of TLRs in relation to gut microbial quantity may contribute to carcinogenesis.     

Evaluation of performance enhancing proxies in internet over satellite

Performance enhancing proxies (PEPs) are widely used to improve the performance of TCP over high delay‐bandwidth product links and links with high error probability. In this paper we analyse the performance of using TCP connection splitting in combination with web caching via traces obtained from a commercial satellite system. We examine the resulting performance gain under different scenarios, including the effect of caching, congestion, random loss and file sizes. We show, via analysing our measurements, that the performance gain from using splitting is highly sensitive to random losses and the number of simultaneous connections, and that such sensitivity is alleviated by caching. On the other hand, the use of a splitting proxy enhances the value of web caching in that cache hits result in much more significant performance improvement over cache misses when TCP splitting is used. We also compare the performance of using different versions of HTTP in such a system. Copyright © 2003 John Wiley & Sons, Ltd.     

Real-time processing and compression of DNA microarray images.

In this paper, we present a pipeline architecture specifically designed to process and compress DNA microarray images. Many of the pixilated image generation methods produce one row of the image at a time. This property is fully exploited by the proposed pipeline that takes in one row of the produced image at each clock pulse and performs the necessary image processing steps on it. This will remove the present need for sluggish software routines that are considered a major bottleneck in the microarray technology. Moreover, two different structures are proposed for compressing DNA microarray images. The proposed architecture is proved to be highly modular, scalable, and suited for a standard cell VLSI implementation.     

Robust control of polytopic systems by convex optimization

Robust control synthesis of linear time-invariant SISO polytopic systems is investigated using the polynomial approach. A convex set of all stabilizing controllers for a polytopic system is given over an infinite-dimensional space. A finite-dimensional approximation of this set is obtained using the orthonormal basis functions and represented by a set of LMIs thanks to the KYP lemma. Then, an LMI based convex optimization problem for robust pole placement with sensitivity function shaping in two- and infinity-norm is proposed. The simulation results show the effectiveness of the proposed method.     

Multi-objective mixture design and optimisation of steel fiber reinforced UHPC using machine learning algorithms and metaheuristics

Ultra-high-performance concrete (UHPC) is a recent class of concrete with improved durability, rheological and mechanical and durability properties compared to traditional concrete. The production cost of UHPC is considerably high due to a large amount of cement used, and also the high price of other required constituents such as quartz powder, silica fume, fibres and superplasticisers. To achieve specific requirements such as desired production cost, strength and flowability, the proportions of UHPC’s constituents must be well adjusted. The traditional mixture design of concrete requires cumbersome, costly and extensive experimental program. Therefore, mathematical optimisation, design of experiments (DOE) and statistical mixture design (SMD) methods have been used in recent years, particularly for meeting multiple objectives. In traditional methods, simple regression models such as multiple linear regression models are used as objective functions according to the requirements. Once the model is constructed, mathematical programming and simplex algorithms are usually used to find optimal solutions. However, a more flexible procedure enabling the use of high accuracy nonlinear models and defining different scenarios for multi-objective mixture design is required, particularly when it comes to data which are not well structured to fit simple regression models such as multiple linear regression. This paper aims to demonstrate a procedure integrating machine learning (ML) algorithms such as Artificial Neural Networks (ANNs) and Gaussian Process Regression (GPR) to develop high-accuracy models, and a metaheuristic optimisation algorithm called Particle Swarm Optimisation (PSO) algorithm for multi-objective mixture design and optimisation of UHPC reinforced with steel fibers. A reliable experimental dataset is used to develop the models and to justify the final results. The comparison of the obtained results with the experimental results validates the capability of the proposed procedure for multi-objective mixture design and optimisation of steel fiber reinforced UHPC. The proposed procedure not only reduces the efforts in the experimental design of UHPC but also leads to the optimal mixtures when the designer faces strength-flowability-cost paradoxes.

     

VPR-Bench: An Open-Source Visual Place Recognition Evaluation Framework with Quantifiable Viewpoint and Appearance Change

International Journal of Computer Vision - Visual place recognition (VPR) is the process of recognising a previously visited place using visual information, often under varying appearance...     

Adaptive synchronization of master–slave systems with mixed neutral and discrete time‐delays and nonlinear perturbations

This paper investigates the delay‐dependent adaptive synchronization problem of the master and slave structure of linear systems with both constant neutral and time‐varying discrete time‐delays and nonlinear perturbations based on the Barbalat lemma and matching conditions. An adaption law which includes the master‐slave parameters is obtained by using the Lyapunov functional method and inequality techniques to synchronize the master‐slave systems without the knowledge of upper bounds of perturbation terms. Particularly, it is shown that the synchronization speed can be controlled by adjusting the update gain of the synchronization signal. A numerical example has been given to show the effectiveness of the method. Copyright © 2011 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society     

Nonflat surface level pyramid: a high connectivity multidimensional interconnection network

Parallel machines are extensively used to increase computational speed in solving different scientific problems. Various topologies with different properties have been proposed so far and each one is suitable for specific applications. Pyramid interconnection networks have potentially powerful architecture for many applications such as image processing, visualization, and data mining. The major advantage of pyramids which is important for image processing systems is hierarchical abstracting and transferring the data toward the apex node, just like the human being vision system, which reach to an object from an image. There are rapidly growing applications in which the multidimensional datasets should be processed simultaneously. For such a system, we need a symmetric and expandable interconnection network to process data from different directions and forward them toward the apex. In this paper, a new type of pyramid interconnection network called Non-Flat Surface Level (NFSL) pyramid is proposed. NFSL pyramid interconnection networks constructed by L-level A-lateral-base pyramids that are named basic-pyramids. So, the apex node is surrounded by the level-one surfaces of NFSL that are the first nearest level of nodes to apex in the basic pyramids. Two topologies which are called NFSL-T and NFSL-Q originated from Trilateral-base and Quadrilateral-base basic-pyramids are studied to exemplify the proposed structure. To evaluate the proposed architecture, the most important properties of the networks are determined and compared with those of the standard pyramid networks and its variants.