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Bushman Brad J.; Bonacci Angelicca M.; van Dijk Mirjam; Baumeister Roy F. 《Canadian Metallurgical Quarterly》2003,84(5):1027
Laboratory analog studies investigated the theory that narcissism and reactance contribute to causing rape. In Study 1, narcissism correlated positively with rape-supportive beliefs and negatively with empathy for rape victims. In Study 2, narcissists reported more enjoyment than other men of film depictions that presented consensual, affectionate activity followed by rape (but not in response to either affection or rape alone). In Study 3, narcissists were more punitive than other men toward a female confederate who refused to read a sexually arousing passage aloud to them. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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Björn Sten Mark Kretzschmar Paul Bergelt Daniel Göhler Fabian Firmbach Ronny Köcher Andreas Heft 《Aerosol science and technology》2020,54(10):1124-1134
Abstract For the purpose of silica surface layer modulation, a pneumatic-controlled two-substance atomizer with inertia-based coarse droplet separation was operated at different system pressures for tetraethyl orthosilicate precursor aerosol supply during combustion chemical vapor deposition. A comprehensive testing study was performed to characterize the atomizer’s performance characteristics, initial precursor aerosols at the atomizer’s outlet, transformed aerosols before combustion, combustion aerosols and formed layers. Laser diffraction spectrometry, differential electrical mobility analyses and condensation particle counting were used for aerosol characterization with regard to particle size and particle production quantities. Layers were characterized by scanning electron microscopy, atomic force microscopy, spectral ellipsometry, water contact angle measurements and light transmission concerning geometric properties (thickness, surface structure and roughness) and physical behaviors (i.e., optical behaviors, hydrophobicity). Results show a quasi-linear relationship of the ejection mass flow of the pneumatic-controlled atomizer and geometric layer properties which again show a direct relationship to the physical properties. No correlation was found between the aerosols before combustion and the combustion aerosols since the majority of combustion aerosol particles are synthesized solely from the gas phase based on evaporated precursor material. Copyright © 2020 American Association for Aerosol Research 相似文献
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本文介绍了民主德国关于堆焊工艺的一些最新研究成果以及为提高焊接自动化程度对设备的研究和发展。哈雷中央焊接研究所研制的堆焊-裁荷-填充材料-工艺系统(“A—B—Z—V”),作为选择工艺及填充材料的依据,从构件分析出发,生产了用于旋转件的特种程序的机器人ZIS12—63.孔堆焊设备ZIS12—96,轨道堆焊机ZIS13—43,轻便堆焊机ZIS15—40.以及用于侧板堆焊的机器人和煤球模型堆焊机器人。 相似文献
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Wilfried M. Post Mirjam A. A. Huis in ’t Veld Sylvia A. A. van den Boogaard 《Personal and Ubiquitous Computing》2008,12(3):223-235
Many attempts are underway for developing meeting support tools, but less attention is paid to the evaluation of meetingware.
This article describes the development and testing of an instrument for evaluating meeting tools. First, we specified the
object of evaluation—meetings—by means of a set of input, process, and outcome factors. Then, we designed the process of evaluation,
consisting of, first, the generation of meeting behavior in the form of a controlled series of meetings within the context
of a project and, second, the measurement of the identified meeting factors. To measure these factors, a rating scale, questionnaires,
and information flow analysis were used. Next, the instrument was tested, and the factors for successful meetings were determined
in 13 projects in which four participants had to meet four times. The evaluation instrument proved to be a reliable and useful
aid for the development and improvement of meeting tools. 相似文献
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Aristotle long ago divided kinds of study into techn and epistm,which we can roughly translate into the modern terms artand science. It is certainly the case that computationaldialectologists do well with the Art (techn), in our technicalconstruction and execution of statistical experiments, and wehave two different prominent models to choose from, each onecorresponding to a mode of scientific discovery, either to deductiveor to inductive scientific procedure. But that in itself shouldnot be the whole story. The Science (epistm) of computationaldialectology lies in the creation of arguments from our statisticalresults that are appropriate to the scientific procedure thatmotivates us. It is not so clear that computational dialectologistshave done so well with their Science. What do the results ofthe technical work really mean? In what way are they associatedwith particular choices of linguistic theory? Is it the casethat, after all of our technical hard work, we find only whatwe are looking for? In this paper, I will suggest that an appropriateuse of the technical results of computational dialectology requiresthat practitioners take a more subtle approach to the theorythat motivates the study in the first place, especially to therelationship between perception and production of language. 相似文献
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4‐Biphenylalanine‐ and 3‐Phenyltyrosine‐Derived Hydroxamic Acids as Inhibitors of the JumonjiC‐Domain‐Containing Histone Demethylase KDM4A
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Dr. Ludovica Morera Dr. Martin Roatsch Michael C. D. Fürst Dr. Inga Hoffmann Dr. Johanna Senger Mirjam Hau Dr. Henriette Franz Prof. Dr. Roland Schüle Prof. Dr. Markus R. Heinrich Prof. Dr. Manfred Jung 《ChemMedChem》2016,11(18):2063-2083
Overexpression of the histone lysine demethylase KDM4A, which regulates H3K9 and H3K36 methylation states, has been related to the pathology of several human cancers. We found that a previously reported hydroxamate‐based histone deacetylase (HDAC) inhibitor (SW55) was also able to weakly inhibit this demethylase with an IC50 value of 25.4 μm . Herein we report the synthesis and biochemical evaluations, with two orthogonal in vitro assays, of a series of derivatives of this lead structure. With extensive chemical modifications on the lead structure, also by exploiting the versatility of the radical arylation with aryldiazonium salts, we were able to increase the potency of the derivatives against KDM4A to the low‐micromolar range and, more importantly, to obtain demethylase selectivity with respect to HDACs. Cell‐permeable derivatives clearly showed a demethylase‐inhibition‐dependent antiproliferative effect against HL‐60 human promyelocytic leukemia cells. 相似文献