Suggestions to the article: medical professionalism research characteristics and hotspots

Scientometrics - The article published on 5 July 2021 is well-written and of interest. However, some improvements could be made, such as ten Tables/Figures can be shortened to highlight the focused...     

Antiplatelet Effect and Selective Binding to Cyclooxygenase (COX) by Molecular Docking Analysis of Flavonoids and Lignans

The known flavonoids ginkgetin (1), taiwanhomoflavone A (2), taiwanhomoflavone B (3), and taiwanhomoflavone C (4) and eight known lignans: justicidin B (9), justicidin C (10), justicidin D (11), chinensinaphthol methyl ether (12), procumphthalide A (13), procumbenoside A (15), and ciliatosides A (16) and B (17) were isolated from Cephalotaxus wilsoniana and Justicia species, respectively. The antiplatelet effects of the above constituents on human platelet-rich plasma (PRP) were evaluated. Of the compounds tested on human PRP, compounds 1, 4, 9, and 11 showed inhibition of secondary aggregation induced by adrenaline. Compound 1 had an inhibitory effect on cyclooxygenase-1 (COX-1). Molecular docking studies revealed that 1 and the related compounds apigenin (5), cycloheterophyllin (6), broussoflavone F (7), and quercetin (8) were docked near the gate of active site of COX-1. It indicated that the antiplatelet effect of 1, 4, 9, and 11 is partially owed to suppression of COX-1 activity and reduced thromboxane formation. Flavonoids, 1, 5, 6, 7, and 8 may block the gate of the active site of COX-1 and interfere the conversion of arachidonic acid to prostaglandin (PG) H₂ in the COX-1 active site.     

加强企业内部经济责任制运行之我见

企业内部经济责任制是众多企业经营管理工作的一项基本管理制度。指标合理、体系完备、主体明确是推行责任制的基础;强化过程监控是保障经济责任制有效运行的必要手段;强化目标管理、严格考核兑现是推行经济责任制的关键。只有科学确定企业总体经营目标、合理分解目标任务、考核奖励公平公正,才能保证企业经济责任制的顺利实施。     

Side-effect localization for lazy, purely functional languages via aspects

Many side-effecting programming activities, such as profiling and tracing, can be formulated as crosscutting concerns and be framed as side-effecting aspects in the aspect-oriented programming paradigm. The benefit gained from this separation of concerns is particularly evident in purely functional programming, as adding such aspects using techniques such as monadification will generally lead to crosscutting changes. This paper presents an approach to provide side-effecting aspects for lazy purely functional languages in a user transparent fashion. We propose a simple yet direct state manipulation construct for developing side-effecting aspects and devise a systematic monadification scheme to translate the woven code to monadic style purely functional code. Furthermore, we present a static and dynamic semantics of the aspect programs and reason about the correctness of our monadification scheme with respect to them.     

二次有理Bèzier曲线曲率单调条件的研究

文中研究并推导出了二次有理 Bèzier曲线的曲率单调条件 .研究结果表明 ,有理 Bèzier曲线比 Bèzier曲线的曲率单调条件具有更大的自由度 .对于任意的三个控制顶点 ,只要两控制边的夹角不小于 90度 ,必定存在一族曲率单调的二次有理 Bèzier曲线 .二次有理 Bèzier曲线不仅可表示曲率单调的抛物线段 ,还可表示曲率单调的椭圆弧和双曲线段 ,这取决于权因子的取值 .     

铸锻件的磁粉检测和渗透检测

比较了磁粉检测和渗透检测两种检测方法的特点。结合经验，总结了两种方法所适用的对象与情况。     

Electrical control of shape of laser beam using axially symmetric liquid crystal cells

This work demonstrates the electrical tuning of laser beam shape using an axially symmetric dye-dope liquid crystal (ASDDLC) device that is fabricated using a photo-alignment method. Various beam shapes can be obtained by linearly polarized Gaussian laser beams through an ASDDLC device under various applied voltages. The far-field intensity patterns generated by laser beams of selected shapes under various applied voltages are simulated, and the results are consistent with experiment. A rotatable petal-shaped beam is obtained by controlling the polarization of the output donut-shaped beam. The tenability of beam shape of light with a wavelength of 1064 nm, which is commonly used in biomedical applications, is also demonstrated.     

基于BP神经网络的乳腺癌患者存活概率的预测分析

本文提出了对乳腺癌的知识进行挖掘及对其有效的网络予以探讨. 在应用各种数据挖掘方法之前,利用所开发的网络找出病情发展的概率. 有关结果有助于医生针对病人的病情进行合理治疗. 为克服数据集的高维度问题并实现数据之间的关联性,本文采用主成分分析法来降低数据维度并找出适用的网络. 运用BP神经网络结构进行了评估,对北京某医院的乳腺癌数据方面BP神经网络的性能进行了分析. 结果表明主成分分析消除了网络输入之间的相关性,降低了网络的输入层数,改善从整体上提高了网络的性能. 最终取得了良好的预测结果.     

Research in progress

Environmental designers and researchers have taken advantage of visual surrogates for problem solving in a variety of physical settings and for theory building in the areas of environmental perception and behaviour. However, validity issues—external validity, ecological validity and incremental validity—have to be considered while selecting an environmental surrogate. In representing water features the dynamic qualities of water, sound and movement, have to be portrayed. A method is described for representing built waterscapes by videotape images, which takes into account these three validity concerns (although the validity of the surrogate is not tested). The surrogate attempts to recognize that human environmental perception is multi-modal and that humans are active participants throughout the environment. Such a surrogate seeks to more realistically reflect actual human environmental experience, but the effectiveness of the videos and their application to non-built settings requires further empirical support.     

Internet-based selling technology and e-commerce growth: a hybrid growth theory approach with cross-model inference

Innovations associated with information and communication technology (ICT) have opened up new opportunities for the global economy and ushered in the age of e-commerce. Our objective in this research is to explore the role of Internet-based selling technology, which acts as technology infrastructure for B2C e-commerce growth at the country level. This study proposes the use of a new hybrid growth theory approach as the theoretical basis for examining exogenous and endogenous factors that influence e-commerce growth over time. We estimate three different models to evaluate their explanatory capabilities. We investigate a panel-corrected feasible generalized least squares regression that incorporates the direct effects of country-level variables. We also specify an endogeneity-adjusted two-stage least squares model and estimate it with an embedded technology adoption function in a simultaneous equation model. This permits the analysis of the relevance of IT infrastructure, as well as reverse causality between e-commerce growth and Internet-based selling technology. We test these models using archival data for four different regions, based on either 24 or 42 countries around the world, depending on the data requirements of the models. Our empirical tests evaluate quasi-production environmental inputs, in which technology determines the environment of production of e-commerce services. Our main finding is that both endogenous variables (e.g., Internet user penetration, capital invested in telecommunication) and exogenous variables (international openness) drive the GDP-normalized level of B2C e-commerce revenues over time. A second main finding is that it is useful to include an embedded technology adoption function in a modeling specification for growth, since growth is founded on the availability of relevant IT infrastructure that is made possible by the availability of venture capital. In addition, B2C e-commerce revenue growth and venture capital also contribute to the adoption of Internet-based selling technology. We discuss our overall approach for the interpretation of the strength of our main findings, as well as the policy implications, and why our hybrid growth theory approach is useful.