Cocaine alters behavior in the rat fetus.

Changes in motor behavior and sensory responsiveness were characterized in rat fetuses on Gestational Day 21 after acute administration of various doses of cocaine. An increase in fetal motor activity was evident in the 3 highest doses (5, 10, and 20 mg/kg). Cocaine-exposed Ss showed reduced facial wiping in behavioral bioassays of cutaneous sensitivity (10 and 20 mg/kg) and chemosensory responsiveness (20 mg/kg). Changes in other behavioral measures indicated that fetuses detected and responded to these stimuli, suggesting that reduced facial wiping was due to a disruption of sensorimotor integration or motor coordination. Study of the fetus in vivo can provide insights into the mechanisms of cocaine's deleterious effects on CNS and behavioral development. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Central administration of cocaine produces age-dependent effects on behavior in the fetal rat.

Rat fetuses were exposed to cocaine, lidocaine, or saline on Gestational Day 20 or 21 to provide information about cocaine effects on behavior during prenatal development. Cocaine was administered into the cisterna magna of individual fetal subjects to restrict effects to the CNS. Behavioral effects of cocaine were compared with lidocaine to help distinguish the effects of cocaine on monoamine systems in the brain from its properties as a local anesthetic. Cocaine promoted 3–5 fold increases in fetal motor activity in the absence of explicit sensory stimulation, in contrast to the slight suppressive effects of lidocaine. Cocaine and lidocaine also reduced coordinated behavioral responses to an artificial nipple. The behavioral effects of cocaine administered into the CNS of fetal subjects suggest specific mechanisms of action on developing neural and behavioral systems in the late prenatal period. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Enhancements of SDR-Based FPGA System for V2X-VLC Communications

This pilot study focuses on a real measurements and enhancements of a software defined radio-based system for vehicle-to everything visible light communication (SDR-V2X-VLC). The presented system is based on a novel adaptive optimization of the feed-forward software defined equalization (FFSDE) methods of the least mean squares (LMS), normalized LMS (NLMS) and QR decomposition-based recursive least squares (QR-RLS) algorithms. Individual parameters of adaptive equalizations are adjusted in real-time to reach the best possible results. Experiments were carried out on a conventional LED Octavia III taillight drafted directly from production line and universal software radio peripherals (USRP) from National Instruments. The transmitting/receiving elements used multistate quadrature amplitude modulation (M-QAM) implemented in LabVIEW programming environment. Experimental results were verified based on bit error ratio (BER), error vector magnitude (EVM) and modulation error ratio (MER). Experimental results of the pilot study unambiguously confirmed the effectiveness of the proposed solution (longer effective communication range, higher immunity to interference, deployment of higher state QAM modulation formats, higher transmission speeds etc.), as the adaptive equalization significantly improved BER, MER and EVM parameters. The best results were achieved using the QR-RLS algorithm. The results measured on deployed QR-RLS algorithm had significantly better Eb/N0 (improved by approx. 20 dB) and BER values (difference by up to two orders of magnitude).