Serial cytological assay of micronucleus induction: a new tool to predict human cancer radiosensitivity

The role of the propeptide sequence and a disulfide bridge between sites 1 and 122 in chymotrypsin has been examined by comparing enzyme activities of wild-type and mutant enzymes. The kinetic constants of mutants devoid of the Cys1-Cys122 disulfide-linked propeptide show that this linkage is not important either for activity or substrate specificity. However this linkage appears to be the major factor in keeping the zymogen stable against non-specific activation. A comparison of zymogen stabilities showed that the trypsinogen propeptide is ten times more effective than the chymotrypsinogen propeptide in preventing non-specific zymogen activation during heterologous expression and secretion from yeast. This feature can also be transferred in trans to chymotrypsinogen; i.e. the chymotrypsin trypsin propeptide chimera forms a stable zymogen.     

Calculated and Experimental Estimation of Absorbed Mechanical Work in Deformation of Synthetic Fibres

Methods are proposed for obtaining the elastic and absorbed components of deformation and mechanical work expended in the region of a nondestructive mechanical effect from the stress-strain diagrams or by calculated prediction. The closeness of the values of the absorbed and correspondingly the elastic components obtained with the measured or predicted stress-strain diagram totally confirm the satisfactory reliability of modeling the physicomechanical properties of a fibre in the form of an integral equation in which the nonlinear-hereditary kernel analytically reflects the activating character of the mechanical effect combined with the concept of the deformation-time analogy in normalized form [5].     

Composite material in the aluminum oxide-zirconium dioxide system

A dispersion-hardened material with average flexural strength 580 ± 40 MPa, which is a promising building material, has been fabricated by introducing a CaO-ZnO-Al₂O₃-SiO₂ eutectic additive and tetragonal zirconium dioxide into aluminum oxide synthesized by calcining the hydroxide. The sintering temperature of this ceramic is 1550°C. The properties of the eutectic of this system are analyzed, and the optimal liquid-phase composition which gives intense sintering of the aluminum oxide is determined. __________ Translated from Steklo i Keramika, No. 4, pp. 12–15, April, 2007.     

Operation of an experimental facility for fabrication of fuel elements and fuel assemblies of the bor-60 containing vibrocompacted fuel

Translated from Atomnaya Énergiya, Vol. 67, No. 5, pp. 320–323, November, 1989.     

Magnetic-Field-Controlled 1D Photonic Crystal Based on a Periodic Bigyrotropic Structure

A theoretical study is reported of the magnetic-field-controlled optical transmission through a stack of identical bilayers in which one layer is bigyrotropic and the other is nonmagnetic and isotropic. An analytical expression for the complex transmittance is derived. The transmittance–wavelength characteristic is examined for different magnetizations and for fixed materials parameters and total number of bilayers. The magnetization dependence of the position, height, and width of the center peak is investigated. The effect is calculated of magnetization on the ellipticity of transmitted light and the angle of optical rotation.     

The contrast enhancement of brain and spinal cord tumors using Gd-DTPA in magnetic resonance tomography with an extra-low magnetic-field intensity

The contrasting agent Gd-DTPA (Magnevist, Schering AG, Germany) was tested when used in magnetic resonance tomography using extra-low (0.04 T) magnetic field intensity in 68 patients with various brain and spine tumors. The agent was injected intravenously in a dose of 0.1 mmol/kg. No complications were found. The tests showed its high efficiency in the diagnosis of brain neoplasms (particularly in malignant intracerebral disorders, meningiomas and neurinomas). Benign astrocytomas induced no noticeable signal intensification on post-contrasting T1-weighed tomograms. In all cases of spinal tumors, the application of Gd-DTPA could specify the extent of tumor invasions, the presence of cysts and identify accessory tumor nodes in one case.     

Use of a mathematical model in predicting the density of glass for controlling a tank furnace

Translated from Steklo i Keramika, No. 1, pp. 11–12, January, 1992.