Cerebral microbleeds (CMBs) are small hemosiderin deposits indicative of prior cerebral microscopic hemorrhage and previously thought to be clinically silent. Recent population‐based cross‐sectional studies and prospective longitudinal cohort studies have revealed association between CMB and cognitive dysfunction. In the general population, CMBs are associated with age, hypertension, and cerebral amyloid angiopathy. In the chronic kidney disease (CKD) population, diminished estimated glomerular filtration rate has been found to be an independent risk factor for CMB, raising the possibility that a uremic milieu may predispose to microbleeds. In the end‐stage renal disease (ESRD) population on hemodialysis, the incidence of microbleeds is significantly higher compared with a control group without history of CKD or stroke. We present an ESRD patient on chronic hemodialysis with a history of gradual cognitive decline and progressive CMBs. Through this case and literature review, we illustrate the need to develop detection and prediction models to treat this frequent development in ESRD patients. 相似文献
This paper presents an energy-efficient switching scheme for successive approximation register (SAR) analogue-to-digital converter (ADC). The proposed scheme employs charge recycling method to keep the capacitor arrays free of transitional energy between bit generations except reset phase. In comparison with the conventional switching scheme, the proposed one achieves 100% transitional energy saving without considering reset phase. In addition, configuration of a 10-bit SAR ADC shows that the proposed switching scheme reduces the capacitor area by 25% compared with the conventional switching scheme. 相似文献
The objective of this paper is to review and document the mine fleet management systems’ models and algorithms. The purpose is to understand the algorithms behind the fleet management systems and the proposed academic solutions in this area to identify any gaps in the current literature and to open up opportunities to establish research questions that need to be addressed in an integrated simulation and optimisation operational planning research framework. In this paper, we review industrial fleet management systems and the main academic algorithms behind such systems. The fleet management systems are divided into three subsequently related problems to review: shortest path, production optimisation and real-time dispatching. Finally, the limitations of current algorithms for fleet management systems are documented in terms of mining practice feasibility and optimality of the solution on large-scale problems. The results of this literature review enable us to evaluate the logical links between major components of an integrated simulation and optimisation operational planning framework with current theory of fleet management systems. 相似文献
Structural equation modeling was used to test theoretically based models in which psychological separation and attachment security variables were related to career indecision and those relations were mediated through vocational self-concept crystallization. In contrast to previous studies, which have found either weak or no support for a relation between separation or attachment security variables and career indecision, results based on a sample of 350 college students indicated that some components of separation and attachment security did relate to career indecision in a theoretically supportable direction. Results also revealed that regardless of whether global or component career indecision measures were used, separation and attachment security effects on indecision were at least partially mediated through vocational self-concept crystallization. The strongest mediated relations were observed for the effects of attachment anxiety and maternal separation. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
This paper deals with a new boundary element method for analysis of the quasistatic problems in coupled thermoelasticity. Through some mathematical manipulation of the Navier equation in elasticity, the heat conduction equation is transformed into a simpler form, similar to the uncoupled-type equation with the modified thermal conductivity which shows the coupling effects. This procedure enables us to treat the coupled thermoelastic problems as an uncoupled one, A few examples are computed by the proposed BEM, and the results obtained are compared with the analytical ones available in the literature, whereby the accuracy and versatility of the proposed method are demonstrated. 相似文献
Statistical machine translation systems are usually trained on large amounts of bilingual text (used to learn a translation
model), and also large amounts of monolingual text in the target language (used to train a language model). In this article
we explore the use of semi-supervised model adaptation methods for the effective use of monolingual data from the source language
in order to improve translation quality. We propose several algorithms with this aim, and present the strengths and weaknesses
of each one. We present detailed experimental evaluations on the French–English EuroParl data set and on data from the NIST
Chinese–English large-data track. We show a significant improvement in translation quality on both tasks. 相似文献
Most of the commonly used hydrological models do not account for the actual evapotranspiration (ETa) as a key contributor to water loss in semi-arid/arid regions. In this study, the HEC-HMS (Hydrologic Engineering Center Hydrologic Modeling System) model was calibrated, modified, and its performance in simulating runoff resulting from short-duration rainfall events was evaluated. The model modifications included integrating spatially distributed ETa, calculated using the surface energy balance system (SEBS), into the model. Evaluating the model’s performance in simulating runoff showed that the default HEC-HMS model underestimated the runoff with root mean squared error (RMSE) of 0.14 m3/s (R2?=?0.92) while incorporating SEBS ETa into the model reduced RMSE to 0.01 m3/s (R2?=?0.99). The integration of HECHMS and SEBS resulted in smaller and more realistic latent heat flux estimates translated into a lower water loss rate and a higher magnitude of runoff simulated by the HECHMS model. The difference between runoff simulations using the default and modified model translated into an average of 95,000 m3 runoff per rainfall event (equal to seasonal water requirement of ten-hectare winter wheat) that could be planned and triggered for agricultural purposes, flood harvesting, and groundwater recharge in the region. The effect of ETa on the simulated runoff volume is expected to be more pronounced during high evaporative demand periods, longer rainfall events, and larger catchments. The outcome of this study signifies the importance of implementing accurate estimates of evapotranspiration into a hydrological model.