城建档案工作中的敬业精神

城建档案工作涉及各行各业、各条战线,是一项科学性极强的工作,城建档案工作者不仅要有广博的知识素养,还要有实事求是的科学态度,一丝不苟的工作作风,尤其需要兢兢业业的敬业精神。     

二硫代磷酸硫化氧钼与硫,磷添加剂的复配特性研究

研究了二烷基二硫代磷酸硫化氧钼（ＭｏＤＴＰ）摩擦改进剂及其与硫、磷、硫－磷型添加剂复合的抗磨减摩性能。试验表明，经过适当复配后，这类合活性元素的添加剂对ＭｏＤＴＰ的抗磨减摩性能均有增效作用，同一类型添加剂的活性愈高，增效作用愈显著。同时利用扫描电镜和Ｘ－射线能谱仪进行摩擦副表面膜的形貌照相及元素分析，对复合作用的机理进行了初步探讨。     

制氢装置转化催化剂失活原因分析及对策

中石化西安分公司制氢装置转化催化剂在短期生产运行过程中,因催化剂积碳导致转化炉管表面出现大面积花斑,近半数炉管出现红管,炉管差压增大,转化出口甲烷含量超标,芳烃穿透.对催化剂失活原因进行细致分析后表明:装置开停车频繁;转化催化剂多次积碳-烧碳使催化剂表面剥蚀破碎、跑损严重为主要原因.针对失活原因制定了相应对策.     

3D image retrieval based on differential geometry and co-occurrence matrix

3D image retrieval approach is a challenging problem in the research of content-based image retrieval. In this paper, a novel retrieval approach combined differential geometry and co-occurrence matrix is presented. Firstly, Gaussian curvature and mean curvature are utilized to represent the inherent characteristic of spatial surface, and then we use co-occurrence matrix to store the shape information of 3D images. Secondly, normalization process is applied to the co-occurrence matrix and the invariants independence of the translation, scaling, and rotation transforms are proved. In comparison with the recent methods, experiments indicate a lower computation complexity and a better retrieval rate to 3D images with slight different shape characteristic.     

高压换热器的设计

换热器的设计在满足工艺条件的情况下必须符合GB l50-1998《钢制压力容器》、GB l51-1999《管壳式换热器》及《压力容器安全技术监察规程》的规定,本文着重介绍了高压换热器的设计。     

自锐性金刚石树脂砂轮磨削性能的研究

本文通过对比磨削试验，研究了自锐性金刚石(CSD)树脂砂轮的磨削性能。试验结果表明，由于CSD形状小规则，有许多凹入角和粗糙表面，树脂结合剂对CSD的把持力较普通金刚石强，所以在磨削各参数相同的条件下，自锐性金刚石砂轮与普通金刚石砂轮相比，其磨削比提高60％以上。且由于CSD的内部为许多单个亚晶粒所组成的镶嵌的颗粒，因此在应力作用下，只有很小的不规则的碎片崩掉，从而在每个颗粒的表面上留下许多新的小切削刃，故其加工工件的表面粗糙度值较低。     

Patterning of Discotic Liquid Crystals with Tunable Molecular Orientation for Electronic Applications

The large‐area formation of functional micropatterns with liquid crystals is of great significance for diversified applications in interdisciplinary fields. Meanwhile, the control of molecular alignment in the patterns is fundamental and prerequisite for the adequate exploitation of their photoelectric properties. However, it would be extremely complicated and challenging for discotic liquid crystals (DLCs) to achieve the goal, because they are insensitive to external fields and surface chemistry. Herein, a simple method of patterning and aligning DLCs on flat substrates is disclosed through precise control of the formation and dewetting of the capillary liquid bridges, within which the DLC molecules are confined. Large‐area uniform alignment occurs spontaneously due to directional shearing force when the solvent is slowly evaporated and programmable patterns could be directly generated on desired substrates. Moreover, the in‐plane column direction of DLCs is tunable by slightly tailoring their chemical structures which changes their self‐assembly behaviors in liquid bridges. The patterned DLCs show molecular orientation–dependent charge transport properties and are promising for templating self‐assembly of other materials. The study provides a facile method for manipulation of the macroscopic patterns and microscopic molecular orientation which opens up new opportunities for electronic applications of DLCs.     

PEG分子量对PET—PEG共聚酯结晶性能的影响

通过ＰＥＴ和ＰＥＧ共缩聚，合成了ＰＥＴ—ＰＥＧ共聚酯，采用ＤＳＣ、等温结晶仪、Ｘ衍射分析仪和电子扫描电镜研究了ＰＥＧ分子量对该共聚酯结晶性能的影响。结果表明，在ＰＥＴ分子结构中引入ＰＥＧ链段，能有效提高结晶速度，共聚酯结晶结构与ＰＥＴ类似，但ＰＥＧ不进入晶格中，只起诱导结晶的作用。当ＰＥＧ分子量为４０００时，冷结晶温度Ｔｃｃ降得最低，但热结晶温度Ｔｃ反而比纯ＰＥＴ有所增加，１１０℃结晶速度ｔ１２＝１ｍｉｎ，而纯ＰＥＴ需１２ｍｉｎ。     

Personalized Targeted Therapy for Lung Cancer

Lung cancer has long been recognized as an extremely heterogeneous disease, since its development is unique in every patient in terms of clinical characterizations, prognosis, response and tolerance to treatment. Personalized medicine refers to the use of markers to predict which patient will most likely benefit from a treatment. In lung cancer, the well-developed epidermal growth factor receptor (EGFR) and the newly emerging EML4-anaplastic lymphoma kinase (ALK) are important therapeutic targets. This review covers the basic mechanism of EGFR and EML4-ALK activation, the predictive biomarkers, the mechanism of resistance, and the current targeted tyrosine kinase inhibitors. The efficacy of EGFR and ALK targeted therapies will be discussed in this review by summarizing the prospective clinical trials, which were performed in biomarker-based selected patients. In addition, the revolutionary sequencing and systems strategies will also be included in this review since these technologies will provide a comprehensive understanding in the molecular characterization of cancer, allow better stratification of patients for the most appropriate targeted therapies, eventually resulting in a more promising personalized treatment. The relatively low incidence of EGFR and ALK in non-Asian patients and the lack of response in mutant patients limit the application of the therapies targeting EGFR or ALK. Nevertheless, it is foreseeable that the sequencing and systems strategies may offer a solution for those patients.     

独立学院应用化学特色专业建设的思考

特色专业建设对于新建本科院校具有重要意义。文章从应用化学专业建设的立足点、面向行业需求的应用型教学、加强师资队伍建设、课程设置与人才培养等四个方面阐述了关于应用化学特色专业的建设思考,为该专业的教学建设提供了有益的探索。