The Role of Cell Cycle Regulators in Cell Survival—Dual Functions of Cyclin-Dependent Kinase 20 and p21Cip1/Waf1

The mammalian cell cycle is important in controlling normal cell proliferation and the development of various diseases. Cell cycle checkpoints are well regulated by both activators and inhibitors to avoid cell growth disorder and cancerogenesis. Cyclin dependent kinase 20 (CDK20) and p21^Cip1/Waf1 are widely recognized as key regulators of cell cycle checkpoints controlling cell proliferation/growth and involving in developing multiple cancers. Emerging evidence demonstrates that these two cell cycle regulators also play an essential role in promoting cell survival independent of the cell cycle, particularly in those cells with a limited capability of proliferation, such as cardiomyocytes. These findings bring new insights into understanding cytoprotection in these tissues. Here, we summarize the new progress of the studies on these two molecules in regulating cell cycle/growth, and their new roles in cell survival by inhibiting various cell death mechanisms. We also outline their potential implications in cancerogenesis and protection in heart diseases. This information renews the knowledge in molecular natures and cellular functions of these regulators, leading to a better understanding of the pathogenesis of the associated diseases and the discovery of new therapeutic strategies.     

Effect of complexation of oxidised corn starch with mineral elements on physicochemical properties

The objective of this study was to determine the effect of complexation of oxidised starch with mineral elements on its physicochemical properties. Corn starch was oxidised with sodium hypochlorite and, afterwards, modified with ions of potassium, magnesium and iron. Thus, native and modified starches were analysed for: contents of mineral elements, colour parameters (L*a*b*), water binding capacity and solubility in water at temperature of 60 and 80 °C. Thermodynamic characteristics of gelatinisation by DSC, molecular weight distribution by GPC, intrinsic viscosity and pasting properties by RVA were studied. The efficiency of incorporation of metal ions into oxidised corn starch was about 30%, 20% and 20% for potassium, magnesium and iron ions, respectively. The complexation with potassium ions caused the greatest changes in the molecular weight distribution and the intrinsic viscosity of starches and viscosity of starch pastes. Only modification of starch with iron ions affected the colour parameters of the starch. Incorporation of metal ions into starch resulted also in changes in its water binding capacity and solubility in water.     

基于TS101的PCI接口高速数据采集系统的设计

给出了基于TS101和PCI的双通道数据采集处理系统的设计方案。首先介绍了ADI公司新型数字信号处理(DSP)微处理器TS101和FLYBY数据传输模式,阐述了系统结构和工作原理,最后对如何利用TS101的FLYBY接口提高数据采集、存取效率和数据系统的逻辑控制进行了详细的论述。     

Synthesis of silicon oxynitride from a polymeric precursor

Proton nuclear magnetic resonance (¹H NMR) spectroscopy, Fourier transform infrared (FT-IR) spectroscopy and gas chromatography (GC) have been used to study the products of ammonolysis of dichloromethylsilane in diethyl ether at 0 °C. Results indicate that the major products are trimethylcyclotrisilazane and tetramethylcyclotetrasilazane. Hydrolysis of the cyclosilazanes has also been qualitatively investigated. A simple and useful method for the identification of cyclosilazanes has been developed using the ¹H NMR technique.     

一种改进的运动补偿三维小波视频编码方法

Choi等[1]提出的运动补偿三维子带编码方法是一种具有代表性的高效小波视频编码方法,其编码效率优于国际标准MPEG-2.但是该方法的运算复杂度高,编码时也没有充分利用小波图像的特点.为此,本文对该方法的两项关键技术进行了改进:采用像素域降采样运动估计技术以降低运算复杂度,采用改进的集分裂分层树(Set Partitioning in Hierarchical Trees,SPIHT)方法对三维时/空子带进行更高效的编码.实验结果表明,与原有的算法相比,本文的工作不仅降低了运算复杂度,也进一步提高了编码效率.     

Josephson junction with an amorphous silicon barrier

A Josephson junction Nb/Si/Nb with a 10 nm thick amorphous silicon barrier is studied. The upper electrode contains a 2 nm thick sublayer of amorphous phase adjacent to the barrier, as revealed by cross-sectional TEM. Thus, the junction can be considered as a S-I-N-S system with the N layer represented by amorphous niobium. Peculiarities in the I–V and Δ(T) dependencies are observed and explained as a consequence of a proximity effect present in the upper electrode.     

基于WebGIS和3G的警务指挥调度系统研究与设计

该文针对公安系统的实际需求设计了一个基于WebGIS和3G的警务指挥调度系统。论文首先介绍了警务指挥调度系统的设计思路和总体架构,然后分析了Android开发平台和J2EE开发架构的优点,最后完成了移动终端和中心平台的软件设计并对其实现方法进行了研究。     

动态场景图像去模糊技术研究进展

模糊是图像退化的主要降质因素之一,图像去模糊技术一直是计算机视觉和图像处理领域的一个重要课题,广泛应用于安防、刑侦、交通、金融、医疗图像等领域.首先,对传统去模糊算法进行阐述并说明其存在的问题.然后,在此基础上对现有基于深度学习的图像去模糊方法进行综述并分析了算法存在的优势与不足,着重讨论了基于动态网络的非均匀模糊处理新趋势.最后,结合最新的研究成果,展望了图像去模糊技术未来的发展方向.