电炉镍铁渣重金属浸出研究

通过分析电炉镍铁渣的矿物成分和物相组成,考察不同粒度电炉镍铁渣的重金属含量,采用BCR(Bureau Community of Reference)连续提取方法和调节浸提剂pH值进行电炉镍铁渣的浸出测试。结果表明:粉末状电炉镍铁渣的重金属含量最高,完整电炉镍铁渣的重金属含量小于破损的重金属含量;电炉镍铁渣属于一般工业废物,不属于危险废弃物;水溶态中重金属Cd更容易浸出,重金属Cu、Ni在弱酸环境下更容易浸出,在可还原状态下重金属Cr、Pb和Mn更容易浸出,在可氧化态下Zn和Cu更容易浸出;除Cu和Pb外,pH值的降低会导致电炉镍铁渣中的重金属浸出量增大,呈L型浸出曲线,Cu在碱性环境下会加速浸出,而Pb只有在强碱环境下才会大量浸出,因此在强碱环境下要注意Pb的浸出检测。     

H_2O_2对Apg-2与BCR/ABL蛋白亚细胞定位的影响

目的观察H2O2对Apg-2与BCR/ABL蛋白亚细胞定位的影响。方法用50μmol/L H2O2分别处理BaF3-BCR/ABL、BaF3-MIGR1及过表达Apg-2蛋白的BaF3-BCR/ABL细胞,激光共聚焦显微镜观察细胞内Apg-2、BCR/ABL蛋白的亚细胞定位变化。结果 Apg-2和BCR/ABL蛋白在细胞中定位于胞浆,H2O2损伤可致Apg-2和BCR/ABL蛋白在BaF3-BCR/ABL细胞中发生核转位,Apg-2蛋白过表达可引起BCR/ABL蛋白核转位。结论 Apg-2蛋白在H2O2诱导的损伤后发生核转位,可能与BCR/ABL蛋白相互作用,保护H2O2诱导的细胞损伤。     

Electrokinetic remediation: The use of mercury speciation for feasibility studies applied to a contaminated soil from Almadén

We have chosen the BCR (Bureau Communautaire de Référence) sequential extraction procedure as a speciation analysis to determine the mobility of mercury in the contaminated soil of the Almadén (Spain) mining district. This soil has a high mercury concentration (1000 mg kg⁻¹) in some areas. In previous works, the relationship between the weak-acid soluble fraction and the amount of contaminant recoverable by acid-enhanced electrokinetic remediation (EKR) was shown. In this study, after testing that this relationship is maintained, we test if similar relationships with chelating agents could be established. Recently, several chelating agents were tried and iodide was shown to be quite efficient for the removal of mercury. Thus we have carried out iodide-enhanced EKR experiments at the lab (16 g of soil) and semi-pilot (2 kg) scales. From these experiments it can be concluded that the amount of mercury recoverable by this technique is similar to the one recovered in the batch extraction experiments. Thus, this is another evidence that this kind of experiments can be used for the feasibility studies of the remediation technique. It is also shown that, although the removal efficiency is similar to the one obtained previously for in situ flushing, the time required to achieve this efficiency would be several orders of magnitude shorter for this soil.Nevertheless, the residual Hg present in the weak-acid soluble fraction of the speciation analysis of the soil after the EKR treatment increases with respect to the original contaminated soil, indicating a possible increase of the risks associated to the contaminated site. Therefore, a second EKR treatment is applied to the same soil, this time using acid-enhanced EKR. It is shown that, although almost no Hg was recovered with this technique for the original soil, an important amount can be recovered after the first treatment (iodide-enhanced EKR). Also it is shown that the design and operation of this second technique should be studied carefully due to the rather complex chemistry of the species involved.     

BCR method for solving generalized coupled Sylvester equations over centrosymmetric or anti-centrosymmetric matrix

This paper introduces another version of biconjugate residual method (BCR) for solving the generalized coupled Sylvester matrix equations over centrosymmetric or anti-centrosymmetric matrix. We prove this version of BCR algorithm can find the centrosymmetric solution group of the generalized coupled matrix equations for any initial matrix group within finite steps in the absence of round-off errors. Furthermore, a method is provided for choosing the initial matrices to obtain the least norm solution of the problem. At last, some numerical examples are provided to illustrate the efficiency and validity of methods we have proposed.     

Enhancing TRU burning and Am transmutation in Advanced Recycling Reactor

This paper presents about conceptual designs of Advanced Recycling Reactor (ARR) focusing on enhancement in transuranics (TRU) burning and americium (Am) transmutation. The design has been conducted in the context of the Global Nuclear Energy Partnership (GNEP) seeking to close nuclear fuel cycle in ways that reduce proliferation risks, reduce the nuclear waste in the US and further improve global energy security. This study strives to enhance the TRU burning and the Am transmutation, assuming the development of related technologies in this study, while the ARR based on mature technologies was designed in the previous study. It has followed that the provided TRU burning core is designed to burn TRU at 28 kg/TW_thh, by adding moderator pins of B₄C (Enriched B-11) and the Am transmutation core will be able to transmute Am at 34 kg/TW_thh, by locating Am blanket of AmN around the TRU burning core. It indicates that these concepts improve TRU burning by 40-50% than the previous core and can transmute Am effectively, keeping the void reactivity acceptable.     

应用BCR分析云南蒙自大屯水稻田土壤中重金属形态

以云南蒙自大屯水稻田土壤为研究对象,利用BCR连续提取法分析水稻田土壤样品中Cu、Pb、Zn的赋存特征,这些赋存特征主要包括可交换及碳酸盐结合态、硫化物及有机物结合态和残渣态、Fe/Mn氧化物结合态和残渣态。研究表明应用BCR连续提取法能相对准确地了解该水稻田中重金属的污染情况及潜在释放能力。     

基于SSVEP直接脑控机器人方向和速度研究

直接用思维意图来控制机器人而没有大脑外周神经和肌肉的参与是人类的一个梦想,目前这一研究已成为国际前沿热点和突破点.传统的脑控机器人（Brain-controlled robot,BCR）主要控制其方向,而本文旨在探讨能够同时脑控机器人方向和速度的有效方法.采用可分类目标数多、单次识别率高且训练时间短的稳态视觉诱发电位（Steady state visual evoked potentials,SSVEP）脑机交互（Brain-computer/machine interaction,BCI/BMI）方法,为脑控机器人运动规划了向左、向右、前进和后退4个方向,设计了低速、中速和高速3级运动速度并组合了9个脑控指令;进而比较并优化了SSVEP刺激目标布局间距以及刺激目标闪烁时间,采用典型相关分析（Canonical correlation analysis,CCA）进行识别.结果表明恰当设置SSVEP刺激目标数及其布局间距和刺激目标闪烁时间,可以有效提高被试/用户直接脑控机器人的性能;优化的SSVEP刺激范式三结合适应SSVEP解码的典型相关分析,8名被试脑控机器人到达终点平均用时为2分40秒,最少用时1分29秒;同时,在脑控机器人运动过程中触碰障碍平均次数为0.88,最少碰触次数为0.本研究显示基于SSVEP的脑机交互可以作为直接脑控机器人灵活运动的一种可选方法,能够实现对机器人多个运动方向和多级速度的控制;也证实了适当增加刺激目标间距可以有效提高SSVEP-BCI脑控指令识别的正确率,说明了该脑控方法的性能与刺激被试的范式有关;再次验证了CCA算法在基于SSVEP的脑机交互中具有优良的效果.最后,为克服单一SSVEP范式存在的局限,本研究也尝试把该范式与运动想象相结合的混合范式用于脑控机器人方向和速度,并进行了初步的研究,表明可以进一步改善控制速度和提高被试舒适度.本文可望为基于SSVEP或与运动想象混合的脑机交互应用于分级或精细控制机器人方向和速度提供思路,并为直接脑控机器人技术推向实际应用打下一定的基础.     

BTK and PI3K Inhibitors Reveal Synergistic Inhibitory Anti-Tumoral Effects in Canine Diffuse Large B-Cell Lymphoma Cells

Bruton’s tyrosine kinase (BTK) and phosphoinositide 3-kinase (PI3K) in the B-cell receptor (BCR) signaling pathway are considered potential therapeutic targets for the treatment of B-cell lymphomas, among which, diffuse large B-cell lymphoma (DLBCL) is the most common type. Herein, we comparatively evaluated the single and combined application of the BTK inhibitor ibrutinib and the selective PI3Kγ inhibitor AS-605240 in the canine DLBCL cell line CLBL-1. For further comparison, key findings were additionally analyzed in canine B-cell leukemia GL-1 and human DLBCL cell line SU-DHL-4. While ibrutinib alone induced significant anti-proliferative effects on all cell lines in a dose-dependent manner, AS-605240 only induced anti-proliferative effects at high concentrations. Interestingly, ibrutinib and AS-605240 acted synergistically, reducing cell proliferation and increasing apoptosis/necrosis in all cell lines and inducing morphological changes in CLBL-1. Moreover, the combined application of ibrutinib and AS-605240 reduced relative phosphorylation and, in some instances, the levels of the BTK, AKT, GSK3β, and ERK proteins. Comparative variant analysis of RNA-seq data among canine B- and T-lymphoid cell lines and primary B-cell lymphoma samples revealed potentially high-impact somatic variants in the genes that encode PI3K, which may explain why AS-605240 does not singly inhibit the proliferation of cell lines. The combination of ibrutinib and AS-605240 represents a promising approach that warrants further in vivo evaluation in dogs, potentially bearing significant value for the treatment of human DLBCL.     

自动无功补偿装置中用GTO保护晶闸

针对采用FCT＋FST的自动无功补偿装置的晶闸管的保护及续流问题,提出一种受保护及续流晶闸管控制的R－C旁路电路,将其与电抗器并联而不是与晶闸管并联以保护及续流,给出了R、C参数的计算方法。具有保护及续流灵敏完全、电抗器电流基本连续的优点,并可减少对交流电源侧的谐波污染。     

铬污染建筑废物不同清洗剂的作用效果比较

以海北化工厂的铬污染建筑废物为研究对象,采用改良的BCR顺序提取法研究了不同洗涤药剂对水洗一次后的建筑废物样品总Cr和Cr⁶⁺的清洗效果,分析了6种洗涤药剂对各形态铬的去除效果,并最终筛选出最佳的清洗剂。结果表明:柠檬酸和高浓度盐酸对总Cr和Cr⁶⁺去除率最高,总铬达到90%以上,Cr⁶⁺达到99%以上;高浓度柠檬酸、高浓度盐酸和高浓度醋酸降低了建筑废物的pH值,在酸性条件下Cr⁶⁺被有机酸自发地还原成Cr³⁺,导致Cr⁶⁺具有很好的去除效果;6种洗涤剂均对酸可提取态铬有很好的去除;由于络合作用,柠檬酸对可氧化态存在的Cr³⁺的去除效果很好。综上,柠檬酸是较合适的建筑废物二次洗涤药剂。