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1.
Ligang Yu Yong Li Yukun Yang Caixia Guo Meiping Li 《International Journal of Food Science & Technology》2022,57(7):4646-4655
This study investigated the inhibitory effects of curcumin and piperine on fluorescent advanced glycation end products (fAGEs) formation in a bovine serum albumin (BSA)–fructose model. Model systems of BSA and fructose were prepared, and curcumin or piperine was added. fAGEs and BSA oxidation product (dityrosine, kynurenine and N'-formylkynurenine) contents were determined. The results showed that fAGEs content decreased with increasing concentration of curcumin and piperine (P < 0.05). Addition of curcumin and piperine at 160 µg mL−1 could inhibit fluorescent AGEs by 100% and 93% respectively. Dityrosine and N'-formylkynurenine contents decreased as curcumin and piperine concentration increased (P < 0.05). Furthermore, the result of principal component analysis indicated that curcumin and piperine markedly impeded BSA oxidation, resulting in a lower level of fAGEs in model systems. Therefore, adding curcumin and piperine may facilitate reduced fAGEs levels in BSA–fructose model. 相似文献
2.
Qiaozhi Zhang Yanbo Wang Linglin Fu 《Comprehensive Reviews in Food Science and Food Safety》2020,19(5):2559-2587
Dietary advanced glycation end products (dAGEs) are complex and heterogeneous compounds derived from nonenzymatic glycation reactions during industrial processing and home cooking. There is mounting evidence showing that dAGEs are closely associated with various chronic diseases, where the absorbed dAGEs fuel the biological AGEs pool to exhibit noxious effects on human health. Currently, due to the uncertain bioavailability and rapid renal clearance of dAGEs, the relationship between dAGEs and biological AGEs remains debatable. In this review, we provide the most updated information on dAGEs including their generation in processed foods, analytical and characterization techniques, metabolic fates, interaction with AGE receptors, implications on human health and reducing strategies. Available evidence demonstrating a relevance between dAGEs and food allergy is also included. AGEs are ubiquitous in foods and their contents largely depend on the reactivity of carbonyl and amino groups, along with surrounding condition mainly pH and heating procedures. Once being digested and absorbed into the circulation, two separate pathways can be involved in the deleterious effects of dAGEs: an AGE receptor‐dependent way to stimulate cell signals, and an AGE receptor‐independent way to dysregulate proteins via forming complexes. Inhibition of AGEs formation during food processing and reduction in the diet are two potent approaches to restrict health‐hazardous dAGEs. To elucidate the biological role of dAGEs toward human health, the following significant perspectives are raised: molecular size and complexity of dAGEs; interactions between unabsorbed dAGEs and gut microbiota; and roles played by concomitant compounds in the heat‐processed foods. 相似文献
3.
针对平面并联机构无奇异位置工作空间求解困难、过程繁琐、计算量大等问题,提出了基于CAD求解平面并联机构工作空间的三维螺旋扫描方法。将[n]自由度平面并联机构分解成[n]条支链进行独立分析,得到每条支链下末端执行器的可达区域,再将所有支链可达区域取交集即为平面并联机构工作空间。应用SolidWorks软件建立平面并联机构模型,进行几何特征处理,通过自动求解器求解,将求解过程图形化,快速得到同轴布局5R机构和平面3-RPR并联机构的无奇异位置工作空间。通过同轴布局5R机构的运动学实验,验证了该求解方法的可行性。 相似文献
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In the early design stage, automotive modeling should both meet the requirements of aesthetics and engineering. Therefore, a vehicle CAD (computer aided design) model that can be easily adjusted by feedbacks is necessary. Based on CE-Bézier surface, this paper presents a set of algorithms for parametric segmentation and fairing surface generation in a car model. This model is defined by a simplified automotive template and relevant control points, shape parameters and segmentation parameters, which can be modified to alter the car form efficiently. With this model and the corresponding adjustment method, more than fifty various vehicle models are established in this research according to different parameters. And two methods for calculating similarity index between car models are constructed, which are suitable for brand design trend analysis and modelling design decisionmaking. 相似文献
6.
Application of high‐temperature Fenton oxidation for the treatment of sulfonation plant wastewater
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贴片机脱机编程的快捷方法 总被引:7,自引:4,他引:3
SMT生产线中的大多数加工设备均为数控设备。它们编程所需要的大多数特征数据均可从CAD设计系统中得到。文章介绍了如何从CAD设计系统中导出X、Y坐标数据,并转换成贴片数据的方法和思路,以期引起更多的同行加入到这方面的研究中。 相似文献
9.
介绍如何利用AutoCAD开发适合电气专业使用的CAD系统,通过编制电气CAD的功能菜单,构造电气元件库,增强CAD的专业性能。编制电气CAD可以有效地统一本单位电气制图标准,方便电气工程师使用CAD进行专业设计。 相似文献
10.
基于GIS的水电工程可视化辅助设计理论与方法 总被引:2,自引:0,他引:2
针对当前水电工程设计领域存在的计算机应用水平还有待于提高,设计过程复杂且不直观等情况,在探讨工程可视化辅助设计(VCAD)基本概念及其理论构成体系的基础上,提出了基于GIS的水电工程可视化辅助设计理论与方法,实现了直观方便的设计建模和设计过程的交互控制,以及设计成果的直观形象表达,从而有助于提高工程设计的效率和质量,也为大型水利水电工程设计提供了一种新的辅助手段. 相似文献