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排序方式: 共有8146条查询结果,搜索用时 15 毫秒
1.
Dr. Ying Wang Prof. Dr. Andrew Ewing 《Chembiochem : a European journal of chemical biology》2021,22(5):807-813
Exocytosis plays an essential role in the communication between cells in the nervous system. Understanding the regulation of neurotransmitter release during exocytosis and the amount of neurotransmitter content that is stored in vesicles is of importance, as it provides fundamental insights to understand how the brain works and how neurons elicit a certain behavior. In this minireview, we summarize recent progress in amperometric measurements for monitoring exocytosis in single cells and electrochemical cytometry measurements of vesicular neurotransmitter content in individual vesicles. Important steps have increased our understanding of the different mechanisms of exocytosis. Increasing evidence is firmly establishing that partial release is the primary mechanism of release in multiple cell types. 相似文献
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针对车用柴油酸度等性质测定过程繁琐,采用衰减全反射样品池测定车用柴油的红外光谱,用偏最小二乘法(PLS)建立红外光谱测定车用柴油酸度、密度、闪点和凝点的4个校正模型,验证标准误差分别为0.46 mg/(100 mL),0.77kg/m3,2.60 ℃,2.77 ℃,该方法符合标准方法再现性要求。与标准方法相比,该方法具有无需预处理、操作简单、测量快速、重复性好等优点。 相似文献
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5.
Yoshihiro Yajima 《时间序列分析杂志》1985,6(3):187-201
Abstract. We shall investigate the asymptotic behaviour of the sample autocorrelations and partial autocorrelations of a multiplicative ARIMA process and derive their limiting distributions. Some simulations are presented to illustrate the results obtained. 相似文献
6.
Y. Xiang Y. B. Zhao G. W. Wei 《International journal for numerical methods in engineering》2002,55(8):947-971
Part 2 of this series of two papers presents the applications of the discrete singular convolution (DSC) algorithm. The main purpose of this paper is to explore the utility, test the accuracy and examine the convergence of the proposed approach for the vibration analysis of rectangular plates with internal supports. Both partial internal line supports and complex internal supports are considered for 21 square plates of various combinations of edge support conditions. The effects of different size, shape and topology of the internal supports and different boundary conditions on the vibration response of plates are investigated. The partial internal line supports may vary from a central point support to a full range of cross or diagonal line supports. Several closed‐loop supports, such as ring, square and rhombus, and their combinations are studied for complex internal supports. Convergence and comparison studies are carried out to establish the correctness and accuracy of the DSC algorithm. The DSC results are compared with those in the available literature obtained by using other methods. Numerical results indicate that the DSC algorithm exhibits controllable accuracy for plate analysis and shows excellent flexibility in handling complex geometries, boundary conditions and support conditions. Copyright © 2002 John Wiley & Sons, Ltd. 相似文献
7.
ZHANG Liqing WU Xiaohua 《武汉理工大学学报(材料科学英文版)》2005,20(3):119-121
1IntroductionWuweizi is a traditional Chinese herb,usually usedto cure cough,asthma,neurasthenic,hepatitisetc.Theactive ingredients in wuweizi are5%-22%lignan,themain components of which include deoxyschizandrin,schizandrin andγ-Schizandrin.Forthe purpos… 相似文献
8.
G. Ranzi M. A. Bradford B. Uy 《International journal for numerical methods in engineering》2004,61(5):657-672
The use of the conventional semi-analytical stiffness method in finite element analysis, in which interpolation polynomials are used to develop the stiffness relationships, leads to problems of curvature locking when beam-type elements are developed for composite members with partial interaction between the materials of which it is comprised. The curvature locking phenomenon that occurs for composite steel–concrete members is quite well reported, and the general approach to minimizing the undesirable ramifications of curvature locking has been to use higher-order polynomials with increasing numbers of internal nodes. This paper presents an alternate formulation based on a direct stiffness approach rather than starting from pre-defined interpolation polynomials, and which does not possess the undesirable locking characteristics. The formulation is based on a more general approach for a bi-material composite flexural member, whose constituent materials are joined by elastic shear connection so as to provide partial interaction. The stiffness relationships are derived, and these are applied to a simply supported and a continuous steel–concrete composite beam to demonstrate the efficacy of the method, and in particular its ability to model accurately both very flexible and very stiff shear connection that causes difficulties when implemented in competitive semi-analytical algorithms. Copyright © 2004 John Wiley & Sons, Ltd. 相似文献
9.
河口水流、波浪、潮流、泥沙、河床变形二维数学模型 总被引:19,自引:0,他引:19
根据河口“波浪掀沙,潮流输沙”的泥沙运动机制,引入“波浪幅射应力”反应波浪对水体和泥沙的驱动力.考虑波浪对底部泥沙作用力、波浪对水流挟沙能力的影响及风场对水流和泥沙运动的影响.同时考虑泥沙粒径大小、水体含盐度、含沙量及水流紊动程度等因素对絮凝沉速的影响.用ADI算法求解沿水深平均方程,破开算子法解悬移质不平衡输沙方程及河床变形方程,引入通度概念处理岸滩不规则边界,建立河口水流、波浪、潮流、泥沙、河床变形二维数学模型.通过实测资料及卫星摇感图像对所建数学模型进行检验,表明它可以较好地预测河口泥沙的运动 相似文献
10.
Mamata Mukhopadhyay Sameer V Dalvi 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》2005,80(4):445-454
A supercritical antisolvent (SAS) process is employed for production of solid nanoparticles from atomized droplets of dilute solution in a flowing supercritical carbon dioxide (SC CO2) stream by attaining extremely high, very rapid, and uniform supersaturation. This is facilitated by a two‐way mass transfer of CO2 and solvent, to and from the droplet respectively, rendering rapid reduction in equilibrium solubility of the solid solute in the ternary solution. The present work analyses the degree of supersaturation and nucleation kinetics in a single droplet of cholesterol solution in acetone during its flight in a flowing SC CO2 stream. Both temperature and composition are assumed to be uniform within the droplet, and their variations with time are calculated by balancing the heat and mass transfer fluxes to and from the droplet. The equilibrium solubility of cholesterol with CO2 dissolution has been predicted as being directly proportional to the Partial Molar Volume Fraction (PMVF) of acetone in the binary (CO2–acetone) system. The degree of supersaturation has been simulated up to the time required to attain almost zero cholesterol solubility in the droplet for evaluating the rate of nucleation and the size of the stable critical nuclei formed. The effects of process parameters have been analysed in the pressure range of 7.1–35.0 MPa, temperature range of 313–333 K, SC CO2 flow rate of 0.1136–1.136 mol s?1, the ratio of the volumetric flow rates of CO2‐to‐solution in the range of 100–1000, and the initial mole fraction of cholesterol in acetone solution in the range of 0.0025–0.010. The results confirm an extremely high and rapid increase in degree of supersaturation, very high nucleation rates and stable critical nucleus diameter of the order of a nanometre. Copyright © 2005 Society of Chemical Industry 相似文献