首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   4473篇
  免费   478篇
  国内免费   196篇
电工技术   965篇
综合类   428篇
化学工业   601篇
金属工艺   114篇
机械仪表   97篇
建筑科学   154篇
矿业工程   94篇
能源动力   53篇
轻工业   1743篇
水利工程   46篇
石油天然气   51篇
武器工业   10篇
无线电   90篇
一般工业技术   192篇
冶金工业   116篇
原子能技术   90篇
自动化技术   303篇
  2024年   19篇
  2023年   42篇
  2022年   160篇
  2021年   163篇
  2020年   150篇
  2019年   108篇
  2018年   115篇
  2017年   132篇
  2016年   162篇
  2015年   180篇
  2014年   229篇
  2013年   277篇
  2012年   358篇
  2011年   355篇
  2010年   247篇
  2009年   262篇
  2008年   236篇
  2007年   298篇
  2006年   330篇
  2005年   235篇
  2004年   210篇
  2003年   153篇
  2002年   145篇
  2001年   98篇
  2000年   83篇
  1999年   61篇
  1998年   56篇
  1997年   34篇
  1996年   48篇
  1995年   44篇
  1994年   29篇
  1993年   19篇
  1992年   22篇
  1991年   14篇
  1990年   14篇
  1989年   9篇
  1988年   10篇
  1987年   11篇
  1986年   4篇
  1984年   6篇
  1982年   5篇
  1981年   3篇
  1976年   1篇
  1975年   1篇
  1964年   1篇
  1962年   2篇
  1961年   1篇
  1958年   1篇
  1957年   1篇
  1955年   1篇
排序方式: 共有5147条查询结果,搜索用时 15 毫秒
1.
Tuna cooking juice is a by‐product from the tuna canning industry. In this study, tuna cooking juice was hydrolysed by proteases extracted from the spleen. Tuna cooking juice showed the highest ACE inhibitory and Ca‐binding activities after hydrolysis for 270 and 180 min, respectively. The hydrolysate was further fractionated by ultrafiltration. The permeate exhibited highest ACE inhibitory and Ca‐binding activities when passed through 1 and 5 kDa cut‐off membranes, respectively. Gel filtration chromatography was used to determine the MW of bioactive peptides that exhibited highest ACE inhibitory and Ca‐binding activities. Those peptides that exhibited highest ACE inhibitory and Ca‐binding activities were the MW range of 238–829 Da and 1355–1880 Da, respectively. These results suggest that the tuna cooking juice and the spleen protease extract are a potential source of bioactive peptides that can be utilised as bioactive ingredients in functional food and nutraceuticals.  相似文献   
2.
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease-19 (COVID-19) being associated with severe pneumonia. Like with other viruses, the interaction of SARS-CoV-2 with host cell proteins is necessary for successful replication, and cleavage of cellular targets by the viral protease also may contribute to the pathogenesis, but knowledge about the human proteins that are processed by the main protease (3CLpro) of SARS-CoV-2 is still limited. We tested the prediction potentials of two different in silico methods for the identification of SARS-CoV-2 3CLpro cleavage sites in human proteins. Short stretches of homologous host-pathogen protein sequences (SSHHPS) that are present in SARS-CoV-2 polyprotein and human proteins were identified using BLAST analysis, and the NetCorona 1.0 webserver was used to successfully predict cleavage sites, although this method was primarily developed for SARS-CoV. Human C-terminal-binding protein 1 (CTBP1) was found to be cleaved in vitro by SARS-CoV-2 3CLpro, the existence of the cleavage site was proved experimentally by using a His6-MBP-mEYFP recombinant substrate containing the predicted target sequence. Our results highlight both potentials and limitations of the tested algorithms. The identification of candidate host substrates of 3CLpro may help better develop an understanding of the molecular mechanisms behind the replication and pathogenesis of SARS-CoV-2.  相似文献   
3.
4.
抗日战争胜利初期,国共内战迫在眉睫。为挽救危局,强国富民,中间人士提出所谓中间路线,企图走“第三条道路”实现和平建国。在反动政府的强力弹压和中共的教育帮助下,中间路线退出历史舞台。民主党派的转型历程充分昭示了中国人民在中共领导下走上新民主主义道路的必然性。  相似文献   
5.
Racemic amino acid esters were optically resolved via hydrolysis in organic solvents by the catalysis of an industrial alkaline protease, “Alcalase”. The products which were composed mainly of L-amino acids were insoluble and easily separated by filtration. The activity of the enzyme and enantiomeric excess of the products were significantly dependent on the nature of solvent and the water content in the reaction media. Generally, high values of enantiomeric excess were obtained at low water contents. Many natural and unnatural amino acids were resolved by this method.  相似文献   
6.
Cajanus trypsin inhibitor (CTI) and Cajanus trypsin-chymotrypsin inhibitor (CTCI) previously purified from cv TAT-10 were further characterised. The modification of the inhibitors revealed the presence of lysine at the trypsin reactive site in both CTI and CTCI. Modification of tyrosine at the reactive site of CTCI did not abolish chymotrypsin inhibition suggesting the presence of leucine or phenylalanine as reported in other chymotrypsin inhibitors. CTCI did not contain tryptophan. Dissociation constants for the inhibitors with bovine trypsin were in the region of 0.69 nmol (CTCI) and 0.029 nmol (CTI). Although the protease inhibitors lost their inhibitory activity on exposure to 2-mercaptoethanol they remained attached to the enzyme. The inhibitors were not very effective against the protease from Helicoverpa armigera which is a serious field pest of Cajanus. Dissociation constants for the inhibitors with the larval enzyme were in the region of 100 nmol.  相似文献   
7.
本文介绍了给水联合处理的原理及其优点以及在望亭电厂的1台300MW亚临界燃油直流炉上进行这项处理的工业性试验的过程、效果及存在问题。最后作者对给水联合处理能否取得成效的关键提出了意见。  相似文献   
8.
陈彭年  贺建勋 《控制与决策》1991,6(5):327-331,365
本文考虑了单输人中立型时滞系统的镇定问题。利用Byrnes等人提出的中立型时滞系统的模型,我们证明:如果系统是非奇异的,则系统可镇定的充要条件是其谱可镇定。  相似文献   
9.
Biological and technological systems process information by means of cascades of signals. Be they interacting genes, spiking neurons or electronic transistors, information travels across these systems, producing, for each set of external conditions, an appropriate response. In technology, circuits performing specific complex tasks are designed by humans. In biology, however, design has to be ruled out, confronting us with the question of how these systems could have arisen by accumulation of small changes. The key factor is the genotype-phenotype map. With the exception of RNA folding, not much is known about the exact nature of this mapping. Here, we show that structure of the genotype-phenotype map of simple feed-forward circuits is very close to the ones found in RNA; they have a large degree of neutrality, by which a circuit can be completely rewired keeping its input-output function intact, and there is a relatively small neighbourhood of a given circuit containing almost all the phenotypes.  相似文献   
10.
An earlier neural network analysis of processing of steel plates through hot rolling was subjected to a further refined analysis through some flexible neural networks that evolved using a multi‐objective predator‐prey genetic algorithm. The original data set expressing the Yield Strength and Ultimate Tensile Strength of the rolled slabs in terms of a total of 108 process variables were subjected to a systematic pruning through this evolutionary approach, till the nitrogen content of the steel emerged as the most significant input variable. A theoretical explanation is provided for this slightly unexpected result.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号