Determination of 210pb and 212pb in water and their radiological impact to the public via drinking water

A sensitive and accurate method for determining ultra low-level 210Pb and 212Pb in water samples through double measurements was developed.Pb was pre-concentrated as hydroxides,separated from alkaline earth elements as PbS precipitate,purified by an anion exchange resin chromatography column,precipitated as PbSO4 for source preparation and counted by a low background β-counter.The procedure was checked with IAEA reference materials,and the results agreed well with the recommended values.Theminimum detectable activity was 0.062 mBq·L-1 for 210Pb and 0.053 mBq·L-1 for 212Pb with a 48 L water sample.Seventeen drinking water samples were analyzed,with a Pb recovery of 88.8?5.5%,and the typical activity concentrations were 0.191?15.1 mBq·L-1 for 210Pb and of 1.12?5.77 mBq·L-1 for 212Pb.The estimated committed effective doses to adult members of the public in Italy due to intake of 210Pb and 212Pb in drinking water were 0.096?7.59 μSv·a-1 and 0.005?0.025 μSv·a-1,respectively.     

基于LPC2129定时器捕获功能的车速信号采集系统

介绍了LPC2129单片机定时器的捕获功能,以及在车速信号采集中的应用。设计了车速信号采集系统的软硬件,应用一种基于周期法的车速采集算法计算车速。提出的车速采集方法,无论在低速测量还是高速测量,都可较好地兼顾测量的精度和实时性,为进一步研究整车动态性能提供保证。通过对上车实验采集数据与车速表读数比较,结果证明了硬件设计...     

基于ADV212的实时图像压缩系统

采用专用图像压缩芯片ADV212设计了一个能对分辨力高、数据量大的图像进行实时压缩的系统.该系统能够根据输入数据率自适应调整压缩比,实时产生JPEG2000格式的码流.ADV212输出的码流经过加密后可以实时输出也可在本系统内存储.实验结果表明,该系统能满足实时性要求,同时所得重建图像具有较好的主观视觉感受和较高的峰值信噪比.     

一种基于ADV212图像压缩的方法

高效的硬件图像压缩系统可以有效的减少图像数据的冗余度,在分析专用编解码芯片ADV212的基础上,设计了一种现场可编程门阵列(FPGA)组合ADV212的图像压缩系统,实现对720×288的静态图像进行JPEG2000压缩.FPGA用来实现时序控制和数据转换,ADV212则进行图像的压缩.本次实验主要是改变图像压缩倍数及小波变换级数,并采用峰值信噪比(peak signal to noise ratio,PSNR)和均方误差(mean squared error,MSE)两个参数来衡量压缩图像的质量.实验结果表明,该系统可实现图像的有效压缩,并且压缩倍数越大图像失真越严重,小波变换级数在3级以上时图像质量较好.     

^212Pb,^212Bi标记金属硫蛋白

研究了用２１２Ｐｂ、２１２Ｂｉ和２１２Ｐｂ－２１２Ｂｉ平衡混合物分别标记金属硫蛋白Ｃｄ－ＭＴ２及这些标记物在ＳｅｐｈａｄｅｘＧ－１００柱上的淋洗行为和衰变趋向。实验结果表明，在生理ｐＨ条件下，Ｃｄ－ＭＴ２首先与２１２Ｂｉ结合，其标记率接近１００％。     

基于降斑处理的SAR图像实时压缩系统

为了对SAR图像进行实时压缩和本地存储,基于FPGA和ADV212芯片,利用空域增强Lee滤波算法,设计实现了SAR图像实时降斑压缩系统。测试结果表明,在降斑处理基础上,系统能对大数据量SAR图像进行压缩,产生JPEG2000格式码流,满足实时性、压缩模式和压缩比可选的要求,可支撑目标探测、区域监控等任务应用。     

Evaluation of the PSMA-Binding Ligand 212Pb-NG001 in Multicellular Tumour Spheroid and Mouse Models of Prostate Cancer

Radioligand therapy targeting the prostate-specific membrane antigen (PSMA) is rapidly evolving as a promising treatment for metastatic castration-resistant prostate cancer. The PSMA-targeting ligand p-SCN-Bn-TCMC-PSMA (NG001) labelled with ²¹²Pb efficiently targets PSMA-positive cells in vitro and in vivo. The aim of this preclinical study was to evaluate the therapeutic potential of ²¹²Pb-NG001 in multicellular tumour spheroid and mouse models of prostate cancer. The cytotoxic effect of ²¹²Pb-NG001 was tested in human prostate C4-2 spheroids. Biodistribution at various time points and therapeutic effects of different activities of the radioligand were investigated in male athymic nude mice bearing C4-2 tumours, while long-term toxicity was studied in immunocompetent BALB/c mice. The radioligand induced a selective cytotoxic effect in spheroids at activity concentrations of 3–10 kBq/mL. In mice, the radioligand accumulated rapidly in tumours and was retained over 24 h, while it rapidly cleared from nontargeted tissues. Treatment with 0.25, 0.30 or 0.40 MBq of ²¹²Pb-NG001 significantly inhibited tumour growth and improved median survival with therapeutic indexes of 1.5, 2.3 and 2.7, respectively. In BALB/c mice, no signs of long-term radiation toxicity were observed at activities of 0.05 and 0.33 MBq. The obtained results warrant clinical studies to evaluate the biodistribution, therapeutic efficacy and toxicity of ²¹²Pb-NG001.     

High Sensitivity FBG Pressure Sensor Based on Mechanical Amplifier and Interrogation Using Tunable FBG Filter

A high sensitivity fiber Bragg grating pressure sensor by using mechanical amplifier is demonstrated. The measured pressure sensitivity is -1.80×10 -4 /MPa, which is about two orders of magnitude better than a simple monomode fiber with an in-fiber grating. The resolution of pressure measurement is 0.015 MPa based on interrogation using tunable fiber grating filter.     

哈达玛变换光谱仪压缩系统研究

基于数字微镜器件（Digital Micro-mirror Device,DMD）的哈达玛变换光谱技术是一种新型的光谱成像技术,在国内很少有专门的文献介绍[1-3]。文中先介绍了本实验采用的哈达玛光谱仪样机的原理以及哈达玛成像光谱仪优于传统模板的独特之处,即获得多通道高能量高信噪比的光谱数据,然后描述对采集到的数据做高信噪比,高分辨率压缩处理,最后说明此方法实时性强、图像失真小、实用价值高、应用范围广。     

遥测视频图像采集压缩系统的设计与实现

由于空间遥测图像的数据量大,通信带宽有限,所以对遥测图像进行压缩编码,节省传输时占用带宽资源和减少数据存储量,才能将遥测信号更可靠、全面地进行传输或是存储到记录器中留待分析使用。综合遥测系统在传输图像时要在尽量小的空间中最大化地采集和传输图像信息的特殊要求,设计采用FPGA+专用视频解码芯片ADV7180来实现视频图像采集模块的功能,采用FPGA+专用图像压缩芯片ADV212来完成视频图像压缩功能的设计。最终实现了压缩率约为25倍,压缩后的数据传输速率达到40 Mbit/s的视频图像采集压缩系统。该系统具有体积小、成本低、可靠性高、开发周期短等优点。