辐射敏感综合症--AT病研究进展

共济失调性毛细血管扩张综合症(AT)是一种单基因突变引起的遗传性疾病，表现为高辐射敏感性、进行性神经退变、免疫缺陷、早衰及易患癌症等。本文综述了AT病的研究概况，包括AT临床症状、AT基因的定位、结构与功能、辐射对AT细胞信号传导的影响、AT基因组不稳定性及基因治疗。     

A simplified cascade current‐source inverter interconnected to a single‐phase three‐wire distribution system and its application to electric energy storage systems with batteries

A novel current source inverter system interconnected to the single‐phase grid is proposed. It has the same construction as the conventional three‐phase current source inverter that is interconnected to the single‐phase three‐wire distribution system. Though the proposed circuit has no output transformer, it can be equivalently performed as the single‐phase double cascade inverter by diverting the pole transformer in the utility system. By controlling the appropriate scheme, the output currents can be obtained as the five‐level waveforms and their distortions can be decreased sufficiently. It is applied to the interactive electric energy storage system with batteries and the basic discharging characteristics are discussed experimentally. © 2004 Wiley Periodicals, Inc. Electr Eng Jpn, 150(2): 50–61, 2005; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/eej.10380     

层次式级联多网络模型及其性能

本文提出了一种层次式级联多网络结构，论述了其训练算法，并验证了该结构的收敛性。这种结构在处理高阶非线性分布数据的分类问题方面具有优良的性能，用北京谱仪事例过滤进行性能测试结果表明，其训练和泛化性能都优于单个ＢＰ网络。     

智能混合控制器在转炉干法除尘中的应用

转炉干法除尘蒸发冷却器出口烟气温度大多数采用常规串级控制方式,但转炉冶炼前期控制效果并不理想.对转炉冶炼过程及蒸发冷却器出口烟气温度的控制难点进行研究,找出常规串级控制方式的缺点,并设计出一种智能混合控制器.采用智能模糊控制器和常规控制器并联的控制方式,对蒸发冷却器出口烟气温度进行控制,控制效果理想.实际应用表明,同常规串级控制器相比,智能混合控制器具有响应快、被控对象稳定等优点.     

基于改进基因表达式程序设计的股票指数预测

介绍基因表达式程序设计方法的基本原理,针对股票指数分析与预测问题,在经典的GEP算法基础上,提出一种基于动态变异算子的改进的GEP算法——IGEP算法,动态变异算子随着进化代数和染色体所含基因数目不同而变化,从而加快了GEP的收敛速度和精确度,对算法进行了复杂度和收敛性分析。设计一种基于IGEP的股票指数分析与预测算法,数值实验结果表明,该算法优于经典GEP算法,具有较广泛的通用性。     

高压饱和气体制备系统饱和室多变量控制研究

高压饱和气体制备系统的饱和室出口压力、流量和温度调节系统是一个相互耦合的三输入三输出系统。针对以上特点采用部分解耦控制策略,压力—流量调节子系统采用静态解耦的专家控制方式,温度调节子系统采用串级模糊PID控制方式。通过仿真试验证明这种控制策略能够获得良好的控制效果。     

HSV-tk基因/GCV系统治疗肿瘤的旁观者效应与缝隙连接关系的研究

目的 探讨单纯疱疹病毒胸苷激酶（HSV－tk）基因／丙氧鸟苷（GCV）系统杀伤肿瘤细胞时旁观者效应与细胞间缝隙连接的关系。方法 用PA317细胞包装STK质粒（逆转录病毒载体介导的HSV-tk基因），形成假逆转录病毒颗粒，转染有缝隙连接的大鼠胶质瘤细胞C6和无缝隙连接的入宫颈癌细胞 Hela，制成 C6 tk+和 Helatk+细胞，将不同比例的C6和 C6 tk+、Hela和 Hela tk+细胞混合，每种比例8孔，培养 24h后 4孔加入含0．5μg/mlGCV的培养基，4孔作对照，6d后用MTT法测量细胞存活率。在两个培养皿中放入周围粘有33mm高滤纸的载玻片，分别接种 C6、C6 tk+细胞。细胞 80%汇合后将载玻片互换，并加入含0．5μg/ml GCV的培养基，6d后观察细胞形态。结果C6细胞组存在旁观者效应，Heal细胞组不存在旁观者效应。培养皿中tk+细胞大部分被杀死,tk-细胞无变化。结论HSV-tk基因/GCV系统杀伤肿瘤细胞时旁观者效应与细胞间缝隙连接有关。     

带附加流的多组分矩形级联的稳态算法

提供一种带附加流的多组分矩形级联的稳态算法,该算法基于对级联主方程的准线性化,通过对级联分离因子逐渐逼近来加速收敛过程。数值计算表明,由稳态法和瞬态法得到的计算结果吻合完好,但稳态法相对于瞬态法能大为缩短计算时间,适合于计算带附加流的矩形级联或其它诸如阶梯形级联等更为复杂的级联。     

Uranium (IV)-(VI) Electron Exchange Reactions in Anion Exchange Resin,Tri-n-Octyl Amine and Tri-Butyl Phosphate

A study has been made of the U(IV)-U(VI) electron exchange reactions taking place between natural U(IV) and depleted U(VI) in anion exchange resin, as well as in TnOA/benzene and TBP/benzene systems.

The exchange rate in the anion exchange resin was smaller than the corresponding rates in 8–10 M HCl, which might be explained by considering that the diffusion of the exchangeable species is much slower in the anion exchange resin than in 8–10 M HCl.

The exchange rates in TnOA/benzene and in TBP/benzene were accelerated by decreasing the concentration of TnOA or TBP in benzene. The reason may be that TnOA and TBP, including the exchangeable species, is more easily diffused in dilute than in concentrated solution.

Based on activation energy values, the mechanism of exchange in the anion exchange resin was estimated to be similar to that in 8–10 M HCl solution, and the corresponding mechanism for TBP/benzene similar to that for the cation exchange resin. In the case of TnOA/benzene, the exchange process was presumed to resemble that of the anion exchange resin, judging from the similarity of ionic species extracted thereinto.