全文获取类型
收费全文 | 130篇 |
免费 | 9篇 |
国内免费 | 1篇 |
专业分类
电工技术 | 1篇 |
综合类 | 1篇 |
化学工业 | 22篇 |
金属工艺 | 1篇 |
机械仪表 | 2篇 |
建筑科学 | 7篇 |
能源动力 | 1篇 |
轻工业 | 77篇 |
石油天然气 | 1篇 |
无线电 | 2篇 |
一般工业技术 | 9篇 |
冶金工业 | 3篇 |
原子能技术 | 9篇 |
自动化技术 | 4篇 |
出版年
2024年 | 1篇 |
2023年 | 3篇 |
2022年 | 2篇 |
2020年 | 2篇 |
2018年 | 1篇 |
2017年 | 1篇 |
2016年 | 5篇 |
2015年 | 2篇 |
2014年 | 7篇 |
2013年 | 15篇 |
2012年 | 10篇 |
2011年 | 23篇 |
2010年 | 9篇 |
2009年 | 9篇 |
2008年 | 6篇 |
2007年 | 13篇 |
2006年 | 6篇 |
2005年 | 4篇 |
2004年 | 4篇 |
2003年 | 2篇 |
2002年 | 3篇 |
2001年 | 4篇 |
2000年 | 1篇 |
1999年 | 1篇 |
1996年 | 4篇 |
1992年 | 1篇 |
1988年 | 1篇 |
排序方式: 共有140条查询结果,搜索用时 15 毫秒
1.
Rapid degradation of the mycotoxin patulin in man quantified by stable isotope dilution assays 总被引:1,自引:0,他引:1
Michael Rychlik 《Food Additives & Contaminants》2003,20(9):829-837
The absorption and degradation of the mycotoxin patulin in man was quantified by using a recently developed stable isotope dilution assay. Application of this currently most sensitive method revealed a patulin content less than 200 ng l -1 in the blood serum of five consumers of apple juice. Likewise, no patulin was found in the serum of a volunteer, whose blood was drawn shortly after consumption of a juice containing a maximum tolerable amount of patulin. In further in vitro experiments, the degradation of patulin by reacting it with whole blood was investigated. After addition of 100 μg patulin to 9 ml blood, only 6.1% of the mycotoxin was detected after 2 min. It was concluded, therefore, that even high naturally occurring concentrations of patulin in foods are quickly degraded before reaching other tissues than the gastrointestinal tract. 相似文献
2.
Anna Michalska Alicja Ceglińska Henryk Zieliński 《European Food Research and Technology》2007,225(3-4):545-551
Rye flours with extraction rate of 100% (wholemeal flour), 95% (brown flour), 90% (brown flour) and 70% (light flour) were
prepared in order to study the relation between flour extraction rates and content of bioactive compounds. The following compounds
were analysed: total phenolic compounds (TPC), total flavonoids (TF), inositol hexaphosphate (IP6), reduced (GSH) and oxidized
(GSSG) glutathione, tocopherols (T) and tocotrienols (T3). The reduced/oxidized glutathione status (GSH/GSSG) of the flours
was examined as a potential index of flour resistance against oxidative stress. The following observations were made in relation
to the flour extraction rates and bioactive compounds contents: (a) milling process caused decrease in content in TPC, TF,
IP6, GSH and GSSG, T and T3, (b) the most resistant against oxidation processes were suggested a brown flours, then light
and finally wholemeal flour, (c) the ratio of tocotrienols to tocopherols (T3/T) was the highest in rye flours with extraction
rate of 100–90% whereas light flour was the poorest source of tocopherols and tocotrienols. The provided data support current
trend to increase number of rye products from wholemeal or brown flours. 相似文献
3.
Differential protein abundance in promastigotes of nitric oxide‐sensitive and resistant Leishmania chagasi strains 下载免费PDF全文
4.
O. Chailapakul P. Aksharanandana T. Frelink Y. Einaga A. Fujishima 《Sensors and actuators. B, Chemical》2001,80(3):193-201
The electrooxidation of homocysteine, glutathione (GSH), 2-mercapto ethanesulfonic acid and cephalexin at boron-doped diamond (BDD) electrodes and glassy carbon (GC) electrodes was investigated by cyclic voltammetry. The oxidation of these sulfur-containing compounds exhibited well-defined irreversible responses. This preliminary study has shown that BDD has better sensitivity than GC. Concentration dependence has been studied and indicated the promise of using BDD electrodes for quantitative determination. All of the compounds displayed recognizable oxidation peaks at BDD electrodes at millimolar concentration levels. Scan rate dependence of GSH has been examined. It was shown that there was no adsorption on the surface of the BDD electrode for the low concentration. 相似文献
5.
Water-gated phthalocyanine transistors: Operation and transduction of the peptide–enzyme interaction
The use of aqueous solutions as the gate medium is an attractive strategy to obtain high charge carrier density (1012 cm−2) and low operational voltages (<1 V) in organic transistors. Additionally, it provides a simple and favorable architecture to couple both ionic and electronic domains in a single device, which is crucial for the development of novel technologies in bioelectronics. Here, we demonstrate the operation of transistors containing copper phthalocyanine (CuPc) thin-films gated with water and discuss the charge dynamics at the CuPc/water interface. Without the need for complex multilayer patterning, or the use of surface treatments, water-gated CuPc transistors exhibited low threshold (100 ± 20 mV) and working voltages (<1 V) compared to conventional CuPc transistors, along with similar charge carrier mobilities (1.2 ± 0.2) x 10−3 cm2 V−1 s−1. Several device characteristics such as moderate switching speeds and hysteresis, associated with high capacitances at low frequencies upon bias application (3.4–12 μF cm−2), indicate the occurrence of interfacial ion doping. Finally, water-gated CuPc OTFTs were employed in the transduction of the biospecific interaction between tripeptide reduced glutathione (GSH) and glutathione S-transferase (GST) enzyme, taking advantage of the device sensitivity and multiparametricity. 相似文献
6.
Traumatic Acid Reduces Oxidative Stress and Enhances Collagen Biosynthesis in Cultured Human Skin Fibroblasts 下载免费PDF全文
Traumatic acid (TA) is a plant hormone (cytokinin) that in terms of chemical structure belongs to the group of fatty acids derivatives. It was isolated from Phaseolus vulgaris. TA activity and its influence on human cells and organism has not previously been the subject of research. The aim of this study was to examine the effects of TA on collagen content and basic oxidative stress parameters, such as antioxidative enzyme activity, reduced glutathione, thiol group content, and lipid peroxidation in physiological conditions. The results show a stimulatory effect of TA on tested parameters. TA caused a decrease in membrane phospholipid peroxidation and exhibited protective properties against ROS production. It also increases protein and collagen biosynthesis and its secretion into the culture medium. The present findings reveal that TA exhibits multiple and complex activity in fibroblast cells in vitro. TA, with its activity similar to unsaturated fatty acids, shows antioxidant and stimulatory effects on collagen biosynthesis. It is a potentially powerful agent with applications in the treatment of many skin diseases connected with oxidative stress and collagen biosynthesis disorders. 相似文献
7.
Ginger is known to possess potent antioxidant and anti-inflammatory properties. Therefore, in vivo studies in rats were initiated to investigate if ginger fed through diet can improve their antioxidant status. Inbred male Wistar/NIN rats were divided into four groups containing six animals per group. The 1st group received a stock diet whereas the 2nd, 3rd and 4th groups were fed with a diet incorporating ginger powder at 0.5%, 1% and 5% levels for a period of one month. After one month of feeding, rats were sacrificed and their livers and kidneys collected for the analysis of antioxidant enzymes like superoxide dismutase (SOD), catalase and glutathione peroxidase (GSHPx), and to estimate lipid peroxidation and protein oxidation. The levels of all the three enzymes, which are the important components of antioxidative defenses, were significantly stimulated in the livers of groups fed with ginger. The significant reduction in lipid peroxidation in livers and kidneys and inhibition of protein oxidative products in livers indicated the antioxidant potential of ginger when consumed naturally through diet. The findings reported suggest that regular intake of ginger through diet can protect against oxidative tissue damage. 相似文献
8.
9.
Robyn S. Lymbury Matthew J. Marino Anthony V. Perkins 《Molecular nutrition & food research》2010,54(10):1436-1444
Oxidative stress has been directly implicated in hypertension and myocardial remodelling, two pathologies fundamental to the development of chronic heart failure. Selenium (Se) can act directly and indirectly as an antioxidant and a lowered Se status leads to a higher risk of cardiovascular disease. This study examined the role of Se on the development of hypertension and subsequent progression to chronic heart failure in spontaneously hypertensive rats (SHR). Three dietary groups were studied: (i) Se‐free; (ii) normal Se (50 μg Se/kg food); and (iii) high Se (1000 μg Se/kg food). Systolic blood pressure and echocardiography were used to detect cardiac changes in vivo. At study end, cardiac tissues were assayed for glutathione peroxidase activity, thioredoxin reductase activity, and protein carbonyls. The major finding of this study was the high heart failure‐related mortality rate in SHRs fed an Se‐free diet (70%). Normal and high levels of dietary Se resulted in higher survival rates of 78 and 100%, respectively. Furthermore, high dietary Se was clearly associated with lower levels of cardiac oxidative damage and increased antioxidant expression, as well as a reduction in disease severity and mortality in the SHR. 相似文献
10.