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1.
Quang-Minh Nguyen Arya Bagus Boedi Iswanto Geon Hui Son Sang Hee Kim 《International journal of molecular sciences》2021,22(9)
Plants rely on multiple immune systems to protect themselves from pathogens. When pattern-triggered immunity (PTI)—the first layer of the immune response—is no longer effective as a result of pathogenic effectors, effector-triggered immunity (ETI) often provides resistance. In ETI, host plants directly or indirectly perceive pathogen effectors via resistance proteins and launch a more robust and rapid defense response. Resistance proteins are typically found in the form of nucleotide-binding and leucine-rich-repeat-containing receptors (NLRs). Upon effector recognition, an NLR undergoes structural change and associates with other NLRs. The dimerization or oligomerization of NLRs signals to downstream components, activates “helper” NLRs, and culminates in the ETI response. Originally, PTI was thought to contribute little to ETI. However, most recent studies revealed crosstalk and cooperation between ETI and PTI. Here, we summarize recent advancements in our understanding of the ETI response and its components, as well as how these components cooperate in the innate immune signaling pathways. Based on up-to-date accumulated knowledge, this review provides our current perspective of potential engineering strategies for crop protection. 相似文献
2.
Yongying Su Yanger Chen Jing Chen Zijin Zhang Jinya Guo Yi Cai Chaoyang Zhu Zhongyuan Li Huaiyu Zhang 《International journal of molecular sciences》2021,22(9)
Puccinia striiformis f. sp. tritici (Pst) is an important pathogen of wheat (Triticum aestivum L.) stripe rust, and the effector protein secreted by haustoria is a very important component involved in the pathogenic process. Although the candidate effector proteins secreted by Pst haustoria have been predicted to be abundant, few have been functionally validated. Our study confirmed that chitin and flg22 could be used as elicitors of the pathogenic-associated molecular pattern-triggered immune (PTI) reaction in wheat leaves and that TaPr-1-14 could be used as a marker gene to detect the PTI reaction. In addition, the experimental results were consistent in wheat protoplasts. A rapid and efficient method for screening and identifying the effector proteins of Pst was established by using the wheat protoplast transient expression system. Thirty-nine Pst haustorial effector genes were successfully cloned and screened for expression in the protoplast. We identified three haustorial effector proteins, PSEC2, PSEC17, and PSEC45, that may inhibit the response of wheat to PTI. These proteins are localized in the somatic cytoplasm and nucleus of wheat protoplasts and are highly expressed during the infection and parasitism of wheat. 相似文献
3.
Multiphase flows consist of interacting phases that are dispersed randomly in space and in time. An additional complication arises from the fact that the flow region of interest often contains irregularly shaped structures. While, in principle, the intraphase conservation equations for mass, momentum, and energy, and their initial and boundary conditions can be written, the cost of detailed fluid flow and heat transfer analysis with explicit treatment of these internal structures with complex geometry and irregular shape often is prohibitive, if not impossible. In most engineering applications, all that is required is to capture the essential features of the system and to express the flow and temperature field in terms of local volume-averaged quantities while sacrificing some of the details. The present study is an attempt to achieve this goal by applying time averaging after local volume averaging.Local volume averaging of conservation equations of mass, momentum, and energy for a multiphase system yields equations in terms of local volume-averaged products of density, velocity, energy, stresses, and field forces, together with interface transfer integrals. These averaging relations are subject to the following length scale restrictions:
dℓL,