D-HPG废水的预处理

D-对羟基苯甘氨酸制药废水 COD高 ,成分复杂。采用 Fe粉及 Fenton试剂预处理 ,COD总去除率高达98%以上。小试确定了 Fe粉加入量为 14 0 g/ L、曝气时间为 7h、Fenton法预处理 D- HPG废水的最佳反应条件 :H2 O2 质量浓度为 2 1.5 g/ L,Fe SO4 质量浓度为 3.8g/ L,氧化时间为 4 h,p H为 5     

新型环氧树脂固化剂2-烷基苯并咪唑的研究

用实验室自制的2-烷基苯并咪唑做环氧树脂固化剂,通过示差扫描量热法(DSC)、凝胶实验、FT IR等方法研究其与环氧树脂E-51的固化过程,发现取代基碳链增加,潜伏性增加,并且有很好的力学性能和吸湿性。初步探讨了2-烷基苯并咪唑的固化机理,结果发现其与烷基咪唑近似,同样遵循Heise固化机理。     

一锅法合成2-溴甲基苯并咪唑和3，4-二氢-1H-喹喔啉-2-酮

以邻苯二胺和溴代乙酸乙酯为原料一步合成了2-溴甲基苯并咪唑和3,4-二氢-1H-喹喔啉-2-酮．研究结果表明,这两种物质的生成具有伴生性．     

碱体系中系列羟基苯基卟啉红外光谱和拉曼光谱性质研究

本文继续深入研究该体系中相关物质的红外光谱和拉曼光谱的性质.论文结果说明,在碱体系中,NaOH只与羟基苯基卟啉周边meso-位的羟基反应形成盐,这个性质与紫外可见光谱性质是一致的.同时这一结果也为研究卟啉与金属的相互作用提供了有益的理论支持.     

对甲基苯甲醛的合成

提出了以对甲基苯甲酸为原料，经2-（4-甲基苯基）苯并咪唑的还原-水解合成对甲基苯甲醛的新方法。并讨论了还原-水解反应的条件。     

Soluble N‐substituted poly(benzimidazole imide)s via C−N coupling reaction

Novel heat‐resistant N‐substituted poly(benzimidazole imide)s (PBIIs) with good solubility were synthesized via a C ? N coupling reaction. A model reaction was carried out to assist in determining the optimal reaction conditions for the polymerization and to elucidate the chemical structures of the polymers. The structures of the resulting polymers were characterized by means of Fourier transform infrared and elemental analysis; the results showed good agreement with the proposed structures. The resulting PBIIs exhibited high glass transition temperatures (T_g > 290 ^oC) and good thermostability (T_5% > 440 ^oC). The thermal behavior in air of the PBII polymers suggests that they can be considered as a new class of high performance polyimides. © 2016 Society of Chemical Industry     

N-吡唑酰基苯并咪唑衍生物的合成研究

设计合成了5个未见文献报道的N-吡唑酰基苯并咪唑类化合物,其结构经元素分析、1HNMR、IR确证.     

Double Repositioning: Veterinary Antiparasitic to Human Anticancer

Drug repositioning, the approach of discovering different uses for existing drugs, has gained enormous popularity in recent years in the anticancer drug discovery field due to the increasing demand for anticancer drugs. Additionally, the repurposing of veterinary antiparasitic drugs for the treatment of cancer is gaining traction, as supported by existing literature. A prominent example is the proposal to implement the use of veterinary antiparasitics such as benzimidazole carbamates and halogenated salicylanilides as novel anticancer drugs. These agents have revealed pronounced anti-tumor activities and gained special attention for “double repositioning”, as they are repurposed for different species and diseases simultaneously, acting via different mechanisms depending on their target. As anticancer agents, these compounds employ several mechanisms, including the inhibition of oncogenic signal transduction pathways of mitochondrial respiration and the inhibition of cellular stress responses. In this review, we summarize and provide valuable information about the experimental, preclinical, and clinical trials of veterinary antiparasitic drugs available for the treatment of various cancers in humans. This review suggests the possibility of new treatment options that could improve the quality of life and outcomes for cancer patients in comparison to the currently used treatments.     

Extraction and characterization of lignins from maize stem and sugarcane bagasse

Lignins were isolated from maize stem and sugarcane bagasse by using mild dioxane or acidic dioxane solution. The result of nitrobenzene oxidation of the isolated lignins shows that there is a high proportion of p‐hydroxyphenyl alcohol in the lignins of maize stem and sugarcane bagasse. The lignins isolated from maize stem and sugarcane bagasse have relatively same value of the weight‐average (M _w = 3405–3868 g mol⁻¹) and number‐average (M _n = 1411–1612 g mol⁻¹) molecular weights, and polydispersity (M _w/M _n = 2.24–2.51). Acidic dioxane treatment did attack the β‐aryl ether structures in lignins, in particular for β‐aryl syringyl ethers, and broke the ester bonds between arabinose and ferulic acid that etherified to lignins, and it also cleaved lots of bonds in hemicellulosic polymer. The proportion of β‐O‐4 (threo) guaiacyl units is higher than that of β‐O‐4 (erthreo) guaiacyl units. The phenyl glycoside and benzyl ether linkages between lignin and hemicelluloses are also demonstrated in NMR analysis. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011     

苯并咪唑基芳醛化合物的合成及其荧光性质研究

以带有取代基的水杨醛和各种带有取代基团的邻苯二胺为原料,合成了7种具有荧光性能的苯并咪唑基芳醛化合物。改进了实验方法,收率提高了20%左右。并使用核磁对产品进行了表征,研究其荧光性能。以2-(2-羟基苯基)苯并咪唑为对照,发现在不同位置引入醛基后荧光均有减弱,其中在苯并咪唑环上连有醛基使荧光强度明显减弱。并发现各种取代基团对苯并咪唑基芳醛化合物的荧光性能均有影响,其中硝基的消光作用明显。实验结果为进一步实验提供了重要的实验依据。