利用高频结构仿真器分析波导魔T

高频结构仿真器（HFSS）是一种微波器件设计软件，该软件界面友好，通过仿真计算减小了调试工作量，使得微波器件的设计变得简单易行。本文利用HFSS对波导魔T进行了仿真分析，得到了该器件的S参数和动、静态场的分布情况，并对该器件进行了优化设计。     

基于Logistic混沌系统与魔方变换的图像加密方案

设计了一种基于Logistic映射与魔方变换的图像加密方案。该方案采用改进的混沌序列二值化方法,并借用魔方变换的思想,将二值序列转换所得的整数序列与图像像素值运算后,对图像的行列分别作循环移位完成对图像的加密。实验结果分析表明,该加密方案具有良好的图像加密效果,对于常见的攻击具有较强的抗干扰能力。     

If Virchow and Ehrlich Had Dreamt Together: What the Future Holds for KRAS-Mutant Lung Cancer

Non-small-cell lung cancer (NSCLC) with Kirsten rat sarcoma (KRAS) mutations has notoriously challenged oncologists and researchers for three notable reasons: (1) the historical assumption that KRAS is “undruggable”, (2) the disease heterogeneity and (3) the shaping of the tumor microenvironment by KRAS downstream effector functions. Better insights into KRAS structural biochemistry allowed researchers to develop direct KRAS(G12C) inhibitors, which have shown early signs of clinical activity in NSCLC patients and have recently led to an FDA breakthrough designation for AMG-510. Following the approval of immune checkpoint inhibitors for PDL1-positive NSCLC, this could fuel yet another major paradigm shift in the treatment of advanced lung cancer. Here, we review advances in our understanding of the biology of direct KRAS inhibition and project future opportunities and challenges of dual KRAS and immune checkpoint inhibition. This strategy is supported by preclinical models which show that KRAS(G12C) inhibitors can turn some immunologically “cold” tumors into “hot” ones and therefore could benefit patients whose tumors harbor subtype-defining STK11/LKB1 co-mutations. Forty years after the discovery of KRAS as a transforming oncogene, we are on the verge of approval of the first KRAS-targeted drug combinations, thus therapeutically unifying Paul Ehrlich’s century-old “magic bullet” vision with Rudolf Virchow’s cancer inflammation theory.     

High resolution solid state 13C n.m.r. of butadiene grafted polypropylene

¹H dipolar decoupled ¹³C n.m.r. experiments with the aid of the magic angle spinning technique have been used to determine the graft content and the isomer content of the polybutadiene grafts in a graft copolymer with isotactic polypropylene.     

磷改性ZSM-5分子筛物化性质和裂解制乙烯性能的研究

The physicochemical features of phosphorus-modified ZSM-5 zeolites (SiO2/Al2O3 molar ratio is 25) were characterized by XRD(X-ray diffraction), BET(Brunauer, Emmett and Teller spcific surface area measurement), NH3-TPD(ammonia temperature-programmed desorption) and MASNMR(magic angle spinning nuclear magnetic resonance), and the performance on catalytic pyrolysis to produce ethylene was investigated with a light hydrocarbon fixed bed micro-reactor with n-octane as feed. The results show that the acid site density, acid intensity and hydrothermal stability of ZSM-5 zeolite were improved by phosphorus modification. When P205 content in ZSM-5 zeolite is higher than 2.5%, phosphorus modification can prevent ZSM-5 zeolite crystal structure transformation from orthorhombic to monoclinic. In addition, the dealumination of ZSM-5 zeolite framework was moderated by phosphorus modification under high temperature hydrothermal treatment. The results of n-octane pyrolysis on phosphorus-modified ZSM-5 zeolites show that ethylene yields of zeolites with different phosphorus content are almost the same under the same n-octane conversion. However, the modified zeolites with higher pyrolysis activity give lower yield of propene, butene and total olefin than lower pyrolysis activity under the same n-octane conversion.     

含能子弹膛内抛射过程的数值模拟

为研究子弹膛内抛射,以某新型结构防空榴弹战斗部为基础,建立含能子弹膛内抛射过程数值模拟数学模型,运用ANSYS/LS-DYNA软件模拟火药燃烧、推板及含能子弹在膛内的运动过程,得到各层含能子弹出膛时相对速度曲线,并将模拟结果与理论估算值进行比较。结果表明:模拟数据可为其结构设计和毁伤威力计算提供参考。     

Figure of merit for environmental SEM and its implications

A recently introduced figure of merit for environmental and low vacuum scanning electron microscopes has now been computed in the full operational pressure range for one commercial instrument. The direct simulation Monte Carlo method has been used in lieu of experimental measurements. The theory of this figure of merit is further consolidated. It is shown that a thin pressure limiting aperture can indeed be used as an optimum reference system for all instruments employing differential pumping in the transfer of an electron beam from high vacuum to high pressure. The implications of the results obtained are discussed both in relation to existing commercial instruments and associated literature to pave the way for future progress in the field.     

Building magical realms: responses to pervasive and locative media technology

Abstract

This paper reports on 12 participatory design workshops involving 216 young people, aged 9 to 16. It discusses responses to existing and proposed locative and pervasive media technologies in gaming, mapping, gifting, game design, bodystorming, and collaborative storytelling activities. Issues of the technomagical in scenario planning are discussed.     

扑克牌猜牌魔术及C++实现

文章对一种扑克牌猜牌魔术进行了详细的分析,给出了一种实现的算法,并用C++语言实现。通过该问题的C++实现,可使学习者清晰地了解解决该魔术的全过程。     

基于3D-Zernike的三维弹痕特征提取技术

本文首次针对三维弹痕数据的三维拓扑结构特性的描述问题,提出基于3D-Zernike的三维特征提取方法。充分利用3D-Zernike描述子的平移,尺度,旋转不变性,信息表达的高效性,面向真实三维弹痕数据进行分析和比较。实验验证了该特征对于三维弹痕数据描述的有效性,3D-Zernike描述子对弹痕的次棱数据的描述表现出很好的同一性和差异性。