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1.
《International Journal of Hydrogen Energy》2022,47(84):35641-35654
The continuous catalytic regenerative (CCR) reforming process is one of the most significant sources of hydrogen production in the petroleum refining process. However, the fluctuations in feedstock composition and flow rate could significantly affect both product distribution and energy consumption. In this study, a robust deviation criterion based multi-objective optimization approach is proposed to perform the optimal operation of CCR reformer under feedstock uncertainty, with simultaneous maximization of product yields and minimization of energy consumption. Minimax approach is adopted to handle these uncertain objectives, and the Latin hypercube sampling method is then used to calculate these robust deviation criteria. Multi-objective surrogate-based optimization methods are next introduced to effectively solve the robust operational problem with high computational cost. The level diagram method is finally utilized to assist in multi-criteria decision-making. Two robust operational optimization problems with different objectives are solved to demonstrate the effectiveness of the proposed method for robust optimal operation of the CCR reforming process under feedstock uncertainty. 相似文献
2.
The number of clinical trials evaluating adipose-derived mesenchymal stem cells (AD-MSCs), platelet-rich plasma (PRP), and biomaterials efficacy in regenerative plastic surgery has exponentially increased during the last ten years. AD-MSCs are easily accessible from various fat depots and show intrinsic plasticity in giving rise to cell types involved in wound healing and angiogenesis. AD-MSCs have been used in the treatment of soft tissue defects and chronic wounds, employed in conjunction with a fat grafting technique or with dermal substitute scaffolds and platelet-rich plasma. In this systematic review, an overview of the current knowledge on this topic has been provided, based on existing studies and the authors’ experience. A multistep search of the PubMed, MEDLINE, Embase, PreMEDLINE, Ebase, CINAHL, PsycINFO, Clinicaltrials.gov, Scopus database, and Cochrane databases has been performed to identify papers on AD-MSCs, PRP, and biomaterials used in soft tissue defects and chronic wounds. Of the 2136 articles initially identified, 422 articles focusing on regenerative strategies in wound healing were selected and, consequently, only 278 articles apparently related to AD-MSC, PRP, and biomaterials were initially assessed for eligibility. Of these, 85 articles were excluded as pre-clinical, experimental, and in vitro studies. For the above-mentioned reasons, 193 articles were selected; of this amount, 121 letters, expert opinions, commentary, and editorials were removed. The remaining 72 articles, strictly regarding the use of AD-MSCs, PRP, and biomaterials in chronic skin wounds and soft tissue defects, were analyzed. The studies included had to match predetermined criteria according to the patients, intervention, comparator, outcomes, and study design (PICOS) approach. The information analyzed highlights the safety and efficacy of AD-MSCs, PRP, and biomaterials on soft tissue defects and chronic wounds, without major side effects. 相似文献
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Veronica Cocetta Vincenzo Quagliariello Francesco Fiorica Massimiliano Berretta Monica Montopoli 《International journal of molecular sciences》2021,22(4)
Resistance to chemotherapy still remains a major challenge in the clinic, impairing the quality of life and survival rate of patients. The identification of unconventional chemosensitizing agents is therefore an interesting aspect of cancer research. Resveratrol has emerged in the last decades as a fascinating molecule, able to modulate several cancer-related molecular mechanisms, suggesting a possible application as an adjuvant in cancer management. This review goes deep into the existing literature concerning the possible chemosensitizing effect of resveratrol associated with the most conventional chemotherapeutic drugs. Despite the promising effects observed in different cancer types in in vitro studies, the clinical translation still presents strong limitations due to the low bioavailability of resveratrol. Recently, efforts have been moved in the field of drug delivery to identifying possible strategies/formulations useful for a more effective administration. Despite the necessity of a huge implementation in this research area, resveratrol appears as a promising molecule able to sensitize resistant tumors to drugs, suggesting its potential use in therapy-refractory cancer patients. 相似文献
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回热损失对磁斯特林制冷循环制冷率的影响 总被引:7,自引:0,他引:7
从铁磁质的磁化强度一般表示式出发,探讨热阻和回热损失对磁斯特林制冷循环性能的影响,导出最大制冷率及其它性能参数。得到了结果适用于以顺磁质为工质的磁斯特林制冷循环。并指出在理想回热条件下的结论也适用于磁卡诺制冷循环。 相似文献
9.
D. P. Phillips, T. E. Ruth, and L. M. Wagner (1993) reported that 1969-1990 California mortality data show that Chinese Americans are particularly vulnerable to diseases that Chinese astrology and traditional Chinese medicine associate with their birth years. For example, because fire is associated with the heart, a Chinese person born in a fire year (such as 1937) is more likely to die of heart disease than is a Chinese person born in a nonfire year. However, many diseases were excluded from this study, some diseases that were included have ambiguous links to birth years, and the statistical tests were indirect. A more complete statistical analysis and independent California mortality data for the years 1960-1968 and 1991-2002 did not replicate the original results. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
10.
从汽轮机回热系统的实际情况出发,运用非线性规划理论和计算机技术,解决了给水焓升设计中的最优分配问题。结合具体实例,针对国产200MW汽轮机回热系统给水焓升的分配进行了说明。 相似文献