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1.
四川盆地上三叠统划分对比研究 总被引:36,自引:6,他引:30
四川盆地上三叠统对比长期存在混乱,给盆地整体评价带来困难。通过岩石地层、地震地层、事件地层及高分辨率旋回地层等多种方法讨论了须家河组与香溪群各岩性段的对比关系,得出了全盆地上三叠统的对比关系;指出须四段底可近似看成等时界面;须家河组下部地层自西向东、向南逐层超覆在雷口坡组之上,上部地层在盆地西北部自东南向西北方向剥蚀层位渐次变老。文章建议四川盆地上三叠统废除“香溪群”,统一使用“须家河组”,以利于对全盆地上三叠统进行油气资源整体评价与深化研究。 相似文献
2.
Charuhas V. Thakar Orfeas Liangos JeanPierre Yared David A. Nelson Srinivas Hariachar Emil P. Paganini 《Hemodialysis international. International Symposium on Home Hemodialysis》2003,7(2):143-147
Background: Acute renal failure (ARF) after cardiac surgery is associated with significant morbidity and mortality, irrespective of the need for dialysis. Previous studies have attempted to identify predictors of ARF and develop risk stratification algorithms. This study aims to validate the algorithm in an independent cohort of patients that includes a significant proportion of female and black patients and compares two different definitions of renal outcome.
Methods: A large single center cardiac surgery database was examined (n, 24,660; 1993–2000) which included 29.9% females and 3.7% black patients. Post‐operative ARF was defined as: a) ARF requiring dialysis, b) > 50% reduction in creatinine clearance relative to baseline or requiring dialysis. Clinical variables related to baseline renal function and cardiovascular disease were used in recursive partitioning analysis for both outcome definitions. Chi‐square goodness of fit analysis was performed to validate the algorithm.
Results: The frequency of post‐operative ARF requiring dialysis ranged between 0.5 and 15.5% based on the risk categories with the area under the receiver operating characteristic (ROC) curve of 0.78. Using the more inclusive definition of ARF, the frequency was significantly higher ranging from 2.6 to 25%(P < 0.001) with an area under ROC curve of 0.65.
Conclusions: The renal risk stratification algorithm is valid in predicting post‐operative ARF in an independent cohort of patients, well represented by differences in gender and race. Since the need for dialysis remains subjective, a more objective and inclusive definition of ARF may help in identifying a larger number of patients 'at‐risk'. 相似文献
Methods: A large single center cardiac surgery database was examined (n, 24,660; 1993–2000) which included 29.9% females and 3.7% black patients. Post‐operative ARF was defined as: a) ARF requiring dialysis, b) > 50% reduction in creatinine clearance relative to baseline or requiring dialysis. Clinical variables related to baseline renal function and cardiovascular disease were used in recursive partitioning analysis for both outcome definitions. Chi‐square goodness of fit analysis was performed to validate the algorithm.
Results: The frequency of post‐operative ARF requiring dialysis ranged between 0.5 and 15.5% based on the risk categories with the area under the receiver operating characteristic (ROC) curve of 0.78. Using the more inclusive definition of ARF, the frequency was significantly higher ranging from 2.6 to 25%(P < 0.001) with an area under ROC curve of 0.65.
Conclusions: The renal risk stratification algorithm is valid in predicting post‐operative ARF in an independent cohort of patients, well represented by differences in gender and race. Since the need for dialysis remains subjective, a more objective and inclusive definition of ARF may help in identifying a larger number of patients 'at‐risk'. 相似文献
3.
Thermal stratification in a mantled hot water storage tank is analysed numerically for different water inlet velocities. The aim is to obtain higher thermal stratification and supply hot water for usage as long as possible. Twelve different water inlet velocities to the hot water storage tank are considered. The numerical method is validated by comparing its results against experimental and numerical results from the literature. It turned out that the results obtained from the numerical analysis have shown very good agreements with the results from previous works. As a result, the water temperature in the tank increases with the increase of the water inlet velocities to the mantle but this increment is not proportional. After a period of operation of 7.2 h, which corresponds to the average sunshine duration in Turkey, temperature increments of 6.5 and 35 K have been estimated for the hot water inlet velocities of 0.01 and 0.3 m s?1, respectively, at a radial distance of 0.1 m and a height of 1 m inside the storage tank. Copyright © 2005 John Wiley & Sons, Ltd. 相似文献
4.
Nadezhda A. Evtushenko Arkadii K. Beilin Erdem B. Dashinimaev Rustam H. Ziganshin Anastasiya V. Kosykh Maxim M. Perfilov Alexandra L. Rippa Elena V. Alpeeva Andrey V. Vasiliev Ekaterina A. Vorotelyak Nadya G. Gurskaya 《International journal of molecular sciences》2021,22(8)
The recessive form of dystrophic epidermolysis bullosa (RDEB) is a crippling disease caused by impairments in the junctions of the dermis and the basement membrane of the epidermis. Using ectopic expression of hTERT/hTERT + BMI-1 in primary cells, we developed expansible cultures of RDEB fibroblasts and keratinocytes. We showed that they display the properties of their founders, including morphology, contraction ability and expression of the respective specific markers including reduced secretion of type VII collagen (C7). The immortalized keratinocytes retained normal stratification in 3D skin equivalents. The comparison of secreted protein patterns from immortalized RDEB and healthy keratinocytes revealed the differences in the contents of the extracellular matrix that were earlier observed specifically for RDEB. We demonstrated the possibility to reverse the genotype of immortalized cells to the state closer to the progenitors by the Cre-dependent hTERT switch off. Increased β-galactosidase activity and reduced proliferation of fibroblasts were shown after splitting out of transgenes. We anticipate our cell lines to be tractable models for studying RDEB from the level of single-cell changes to the evaluation of 3D skin equivalents. Our approach permits the creation of standardized and expandable models of RDEB that can be compared with the models based on primary cell cultures. 相似文献
5.
Larisa Anghel Radu Sascu Ioana Mdlina Zota Cristian Sttescu 《International journal of molecular sciences》2021,22(11)
Non-ischemic dilated cardiomyopathy encompasses a wide spectrum of myocardial disorders, characterized by left ventricular dilatation with systolic impairment and increased risk of sudden cardiac death. In spite of all the therapeutic progress that has been made in recent years, dilated cardiomyopathy continues to be an important cause of cardiac transplant, being associated with an enormous cost burden for health care systems worldwide. Predicting the prognosis of patients with dilated cardiomyopathy is essential to individualize treatment. Late gadolinium enhancement-cardiac magnetic resonance imaging, microvolt T-wave alternans, and genetic testing have emerged as powerful tools in predicting sudden cardiac death occurrence and maximizing patient’s selection. Despite all these new diagnostic modalities, additional tests to complement or replace current tools are required for better risk stratification. Therefore, biomarkers are an easy and important tool that can help to detect patients at risk of adverse cardiovascular events. Additionally, identifying potential biomarkers involved in dilated cardiomyopathy can provide us important information regarding the diagnostic, prognostic, risk stratification, and response to treatment for these patients. Many potential biomarkers have been studied in patients with dilated cardiomyopathy, but only a few have been adopted in current practice. Therefore, the aim of our review is to provide the clinicians with an update on the well-known and novel biomarkers that can be useful for risk stratification of patients with non-ischemic dilated cardiomyopathy. 相似文献
6.
由于目前缺乏对浮式取水口前流场变化规律的研究,以分析水库水温分层对取水口前各断面流速分布影响为目标,依据某水库水温资料,采用k-ε紊流模型对浮式取水口前流场进行三维数值模拟,针对水库水温均一和水温分层的两种情况,研究取水口前流速分布,分析水库水温分层对取水口前各断面流速分布的影响。研究结果表明,在浮式取水口附近,水温均一和水温分层的流速分布存在着差异,这种差距随着取水流量和淹没深度的增大而减小。研究成果可为浮式管型取水设施的应用和运行提供技术支持,为取水水温预测提供理论依据。 相似文献
7.
贾建新 《煤炭加工与综合利用》2002,(5):1-3
在总结了跳汰选煤长期生产实践的基础上 ,引入了准重液的概念 ,提出了跳汰分选过程中按准重液密度分层的假说 ;准重液密度 =(矿粒重力 -流体对矿粒流动阻力 ) 矿粒体积 相似文献
8.
9.
三维数学模型近年来越来越多地被用于研究滨海电厂温排水环境影响问题。海域自由面随潮波动、地形复杂多变,垂向网格的划分方式在一定程度上会影响流场、温度场计算结果。本文以某滨海核电厂为例,采用MIKE 3软件开发斜压三维水动力水温模型,在总分层数即算力保持一致的情况下探究纯sigma分层和垂向混合分层两种分层方式对计算结果的影响。结果表明:两种垂向分层模式对海域潮位的计算精度影响不大,但对有垂向流速梯度的流场刻画会产生一定影响,在近岸海域采用sigma分层模式有利于捕捉垂向流速的变化特征;同时,纯sigma分层方案下,4 ℃最大温升包络面积约为混合分层的4倍,表明不同垂向分层模式可能会对高温升包络面积计算结果产生较为显著的影响。 相似文献
10.
介绍了鞍钢建设公司工程网络计划系统软件的主要功能与特点,并较详细地阐述了系统实现中的几个主要技术问题的处理方法。 相似文献