Mixing characteristics for the single and air-water two-phase flows in miniaturized parallel multichannel-based devices

Investigation on the miniaturized parallel multichannel-based devices packed with glass beads to improve the mass exchange execution is the critical focal point of the current study. One of the essential parameters to specify the miniaturized devices' flow distribution is the residence time distribution (RTD). In the present context, the RTDs of a liquid tracer were investigated for the air-water multiphase flows (concurrent) across the multichannel-based miniaturized devices (comprising of 11 similar dimensional parallel channels). The devices were variable in height and packed with glass beads. The conductivity estimations generated the RTD curves and were addressed by the axial dispersion model (ADM). The fluid-flow rates differed within the range of 5–23 ml min⁻¹. The axial dispersion coefficients and the rate of the specific energy dispersion were investigated. The effects of pressure difference and geometry on the hydrodynamic attributes and mixing properties were well-illustrated, and the new correlations were suggested.     

Investigation of liquid water heterogeneities in large area proton exchange membrane fuel cells using a Darcy two-phase flow model in a multiphysics code

Proper management of the liquid water and heat produced in proton exchange membrane (PEM) fuel cells remains crucial to increase both its performance and durability. In this study, a two-phase flow and multicomponent model, called two-fluid model, is developed in the commercial COMSOL Multiphysics® software to investigate the liquid water heterogeneities in large area PEM fuel cells, considering the real flow fields in the bipolar plate. A macroscopic pseudo-3D multi-layers approach has been chosen and generalized Darcy's relation is used both in the membrane-electrode assembly (MEA) and in the channel. The model considers two-phase flow and gas convection and diffusion coupled with electrochemistry and water transport through the membrane. The numerical results are compared to one-fluid model results and liquid water measurements obtained by neutron imaging for several operating conditions. Finally, according to the good agreement between the two-fluid and experimentation results, the numerical water distribution is examined in each component of the cell, exhibiting very heterogeneous water thickness over the cell surface.     

Experimental investigation of gas-liquid flow in a vertical venturi installed downstream of a horizontal blind tee flow conditioner and the flow regime transition

A venturi device is commonly used as an integral part of a multiphase flowmeter (MPFM) in real-time oil-gas production monitoring. Partial flow mixing is required by installing the venturi device vertically downstream of a blind tee pipework that conditions the incoming horizontal gas-liquid flow (for an accurate determination of individual phase fraction and flow rate). To study the flow-mixing effect of the blind tee, high-speed video flow visualization of gas-liquid flows has been performed at blind tee and venturi sections by using a purpose-built transparent test rig over a wide range of superficial liquid velocities (0.3–2.4 m/s) and gas volume fractions (10–95%). There is little ‘homogenization’ effect of the blind tee on the incoming intermittent horizontal flow regimes across the tested flow conditions, with the flow remaining intermittent but becoming more axis-symmetric and predictable in the venturi measurement section. A horizontal (blind tee) to vertical (venturi) flow-pattern transition map is proposed based on gas and liquid mass fluxes (weighted by the Baker parameters). Flow patterns can be identified from the mean and variance of a fast electrical capacitance holdup measured at the venturi throat.     

Electrochemical Quantification of Neurotransmitters in Single Live Cell Vesicles Shows Exocytosis is Predominantly Partial

Exocytosis plays an essential role in the communication between cells in the nervous system. Understanding the regulation of neurotransmitter release during exocytosis and the amount of neurotransmitter content that is stored in vesicles is of importance, as it provides fundamental insights to understand how the brain works and how neurons elicit a certain behavior. In this minireview, we summarize recent progress in amperometric measurements for monitoring exocytosis in single cells and electrochemical cytometry measurements of vesicular neurotransmitter content in individual vesicles. Important steps have increased our understanding of the different mechanisms of exocytosis. Increasing evidence is firmly establishing that partial release is the primary mechanism of release in multiple cell types.     

Flow state monitoring of gas-water two-phase flow using multi-Gaussian mixture model based on canonical variate analysis

As a highly complex and time-varying process, gas-water two-phase flow is commonly encountered in industries. It has a variety of typical flow states and transition flow states. Accurate identification and monitoring of flow states is not only beneficial to further study of two-phase flow but also helpful for stable operation and economic efficiency of process industry. Combining canonical variate analysis (CVA) and Gaussian mixture model (GMM), a strategy called multi-CVA-GMM is proposed for flow state monitoring in gas-water two-phase flow. CVA is used to extract flow state features from the perspective of correlation between historical data and future data, which solves the cross correlation and temporal correlation of multi-sensor measurement data. GMM calculates the possibility that the current flow state belongs to each typical flow pattern and judges the current flow state by probability indicators. It is conducive to follow-up use of Bayesian inference probability and Mahalanobis distance-based (BID) indicator for flow state monitoring, which avoids repeated traversal of multiple CVA-GMM models and improves the efficiency of the monitoring process. The probability indicators can also be used to analyze transition flow states. The method combining the probabilistic idea of GMM with the deterministic idea of multimodal modeling can accurately identify the current flow state and effectively monitor the evolution of flow state. The multi-CVA-GMM method is validated by using the measured data of the horizontal flow loop of gas-water two-phase flow experimental facility, and its effectiveness is proved.     

有水气藏开发早期可采储量的评价方法

有水气藏是天然气藏中的一个基本气藏类型，其采收率受多种因素的影响，如地面集输压力、井筒混合气水流动的液柱压力和储层物性等，目前普遍采用经验取值、物质平衡和气藏数值模拟等方法进行研究，但由于受开发评价阶段试采资料偏少和气藏数值模拟无法模拟井筒流动等因素的影响，早期采收率计算往往偏差较大，针对这些问题，从气田开发一体化的特点出发，提出了一种全面考虑地层→井筒→地面流动条件下，有水气藏（含凝析有水气藏）发废弃压力的计算方法，发展了利用物质平衡早期预测有水气藏采收率的理论，方法可靠、适用性强，能够推广应用。     

线性二次型最优控制闭环系统极点的必要条件

本文推导了线性二次型（LQ）最优控制闭环系统极点应满足的必要条件，以及与加权阵Q和R的等式关系     

Patterns of discrimination in hiring job applicants with disabilities: The role of disability type, job complexity, and public contact.

Objective: To evaluate the effects of disability type, job complexity, and public contact on hiring decisions. Design and Participants: An Americans With Disabilities Act (ADA; 1990) fact sheet and matched resumes with vocational and medical histories including chronic mental illness, developmental disability, closed head injury, and back injury were provided to 295 undergraduate business-related majors, who rated the applicants' suitability for 2 job positions and work shifts. Results: Findings indicated disparities in ratings of employability as a function of disability type. Paired comparisons yielded complementary findings, with effects of disability type and Disability Type × Job Complexity, but no effects of public contact. Conclusions: Stereotyping and discrimination in employment decisions apparently persist, more than 10 years after the ADA. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

液压转向助力系统能耗特性的分析和比较

 为了提高汽车转向系统的工作效率，利用在典型路面条件下获得的实验统计数据，分析了中位开式和中位闭式两种液压转向助力系统的能量消耗． 经过对4种不同工作原理的转向系统的经济性和环境适应性的评价，指出电动中位闭式系统在节能方面具有明显的优势，但在工程应用中仍有不少技术问题需要进一步解决．     

Measurement and prediction of pressure drop in two-phase flow

Experimental data for air–water two-phase co-current flow in two different pipe diameters were used to test the prediction of pressure drop by a number of existing theories and correlations. Several models are shown to be useful for prediction, particularly with the stratified regimes which have proved difficult to handle in the past. The model suggested by Olujic proved to be of particular value.