气管上段腺样囊性癌的临床病理

目的　探讨气管上段腺样囊性癌的临床病理特征及诊断和鉴别诊断要点。方法　收集2000年1月至2014年2月在北京协和医院确诊的4例气管上段腺样囊性癌病例，通过光镜、免疫组织化学及组织化学染色分析其临床病理特征、免疫组织化学特点、诊断及鉴别诊断要点。结果　4例气管上段腺样囊性癌患者中，男1例，女3例，平均年龄47岁(38~57岁）；既往均无腺样囊性癌病史，1例患者既往有结节性甲状腺肿手术史。镜下检查4例均为筛状/管状型腺样囊性癌，3例累及甲状腺组织，3例累及神经组织，未见淋巴结受累。免疫组织化学染色示4例P16、CD117、BCL2、P63、SMA均阳性，Ki67指数平均8%，TTF1和P53均阴性；4例中基底膜样物胶原Ⅳ阳性；组织化学染色示AB/PAS阳性。术后均接受总剂量为48~56 Gy的放疗，随访6~120个月，平均72.5个月，1例术后96个月复发，3例随访期间无复发及转移。结论　气管上段腺样囊性癌是罕见的原发于气管的低度恶性肿瘤，肿瘤生长缓慢，就诊时多数已侵及甲状腺组织，需要与原发于甲状腺的恶性肿瘤相鉴别，特别是在甲状腺穿刺及术中冰冻检查时。结合电子喉气管镜下表现、典型的形态学及免疫组织化学和组织化学染色有助于准确诊断。手术难以切除干净，术后放疗对延缓疾病复发有一定帮助。     

A Study on Turbo—rotor Multi—fault Diagnosis Based on a Neural Network

The multi-fault phenomena are common in the turbo-rotor system of a liquid rocket engine.As it has many excellent qualities,the neural network might be used to solve the problems of multi-fault diagnasis of a turbo-rotor system.First,the feature expression of a common turbo-rotor fault was studied in order to build up the standard fault pattern and satisfy the need of neural network studying and diagnosing.Then.the turbo-rotor fault identification and diagnosis problems were investigated by using a BP(back-propaga-tion)neural network.According to the BP neural network problems,the parallel BP neural network method of multi-fault diagnosis and classification was presented and investigated.The results indicated that the parallel Bp neural network method could solve the turbo-rotor multi-fault diagnosis problems.     

系统备份及其误区分析

文章对系统备份的几个主要方面进行了讨论，并在此基础上，对系统备分的若干认识误区进行了分析。     

平面近场测试系统在天线测试和诊断中的应用

介绍了天线近场测量的基本原理和HD-1型平面近场测试系统,并对近场测量在实际天线测试中的应用情况、发展方向和应用前景等作了简单的描述。     

Quantitative demonstration and cost considerations of a software fault removal methodology

This paper presents a demonstration of a methodology for fault removal during software development. The methodology encompasses the entire development history, from system and software requirements generation to system test. Thus it considers not only the faults during software testing after formal configuration controls have been invoked, but also the faults discovered prior to that phase: during system and software requirements generation, preliminary design, detailed design and code and unit testing. The agents for fault discovery used in verification and validation are called activities, techniques and tools (AT & Ts) in this paper, each having a certain maximum potential or capability for fault discovery. The AT & Ts considered include the usual specification review activities, and also certain tools not normally applied in ‘standard’ software development, such as automated requirements aids. Application of the methodology yields numbers of residual faults as of each phase of development, including those remaining to be discovered during operations and maintenance. Some previous experience and data on residual faults correspond to these results, indicating that the methodology and choice of parameters are reasonable. The methodology also allows one to calculate a relative loss due to delay in fault discovery, which, as is well known, rises rapidly when faults are not discovered during the phase in which they are generated.     

Assessing continuous bivariate effects among different groups through nonparametric regression models: An application to breast cancer detection

In many applications, the joint effect of two continuous covariates on the target binary response may vary across groups defined by levels of a given factor. A testing procedure that would enable this type of surface-by-factor interactions to be detected has been designed. To accomplish this goal, a logistic generalized additive model (GAM) with bivariate continuous interactions varying across groups defined by levels of a factor is considered. A local scoring algorithm based on local linear kernel smoothers was implemented to estimate the proposed logistic GAM. Bootstrap resampling techniques were used for the purpose of testing for factor-by-surface interactions. Given the high computational cost involved, binning techniques were used to speed up computation in the estimation and testing processes. The adequacy of the bootstrap-based test was assessed by means of a simulation study. If a factor-by-surface interaction is detected in the model, it is then established that the use of the odds-ratio curves is very useful in obtaining a direct interpretation of the fitted model. The benefits of using this methodology when analyzing real data are illustrated by applying the technique to the outputs produced by a computerized system dedicated to the early detection of breast cancer.     

一种自制硬件诊断磁带的方法

牛哲成．一种自制硬件诊断磁带的方法．测并技术，１９９４，１８（２）：１４９～１５４硬件诊断磁带是由用于对计算机硬件系统各组成部分进行功能检查、状态测试和故障检测的诊断测试程序集构成的一种专用工具磁带。本文提出了一种用户在ＰＥ３２００系列计算机裸机环境下自己制作硬件诊断磁带的方法，井涉及到具体的程序实现。用该方法制作的硬件诊断磁带操作简单。对进一步搞好ＰＥ３２００系列计算机的维护，开发完善ＰＥ３２００系列计算机硬件诊断系统具有实际意义。     

Empirical Evaluations of Usage-Based Reading and Fault Content Estimation for Software Inspections

This thesis describes six empirical investigations of two techniques applied to software inspections, namely reading techniques and fault content estimation techniques. The first part of the thesis presents a series of experiments of a novel reading technique called usage-based reading. The second part investigates fault content estimation applied to the software inspection process. The estimation methods used are capture-recapture and curve fitting.     

On the relationship between parity space and approaches to fault detection

Parity space approach and H₂ approach are two important fault detection approaches. This paper studies the relationship between these two approaches, which reveals frequency domain characteristics of the optimal solution of the parity space approach on the one side and provides a numerical solution of the H₂-optimal design of residual generators on the other side.     

A formal model of asynchronous communication and its use in mechanically verifying a biphase mark protocol

We present a formal model of asynchronous communication between two digital hardware devices. The model takes the form of a function in the Boyer-Moore logic. The function transforms the signal stream generated by one processor into that consumed by an independently clocked processor, given the phases and rates of the two clocks and the communications delay. The model can be used quantitatively to derive concrete performance bounds on communications at ISO protocol level 1 (physical level). We use the model to show that an 18-bit/cell biphase mark protocol reliably sends messages of arbitrary length between two processors provided the ratio of the clock rates is within 5% of unity.