Comparison of copper emission rates from wood treated with different preservatives to the environment

This study describes a laboratory method for the estimation of emission from preservative-treated wood in the different situations where emissions could enter the environment for use classes 3 (not in contact with ground) and 4 and 5 (in contact with the ground, fresh water or sea water) according to OECD Guidelines. Samples of scotch pine sapwood (Pinus sylvestris L.) were treated with CCA (1% and 2%), ACQ-1900 (3% and 7%), ACQ-2200 (2%), Tanalith E 3491 (2% and 2.8%), and Wolmanit CX-8 (2%).     

Demand elasticities in OECD: Dynamical aspects

Four models with different lag structures are used to express final energy demand in OECD from 1960–1982 as a function of real GDP and average energy price. The income and long-run price elasticities are not significantly dependent on the model specification, but the Koyck lag scheme, estimated in its distributed lag form, is found to give the most satisfactory results. The statistical properties of the data together with evidence of trends in the elasticities both suggest that the period of falling real prices prior to 1971 is not comparable to the present period. For the period after 1971, an income elsticity of 1.02 and a long-run price elasticity of -0.37 are obtained.     

Dipotassium Glycyrrhizinate on Melanoma Cell Line: Inhibition of Cerebral Metastases Formation by Targeting NF-kB Genes-Mediating MicroRNA-4443 and MicroRNA-3620—Dipotassium Glycyrrhizinate Effect on Melanoma

Glycyrrhizic acid (GA), a natural compound isolated from licorice (Glycyrrhiza glabra), has exhibited anti-inflammatory and anti-tumor effects in vitro. Dipotassium glycyrrhizinate (DPG), a dipotassium salt of GA, also has shown an anti-tumor effect on glioblastoma cell lines, U87MG and T98G. The study investigated the DPG effects in the melanoma cell line (SK-MEL-28). MTT assay demonstrated that the viability of the cells was significantly decreased in a time- and dose-dependent manner after DPG (IC₅₀ = 36 mM; 24 h). DNA fragmentation suggested that DPG (IC₅₀) induced cellular apoptosis, which was confirmed by a significant number of TUNEL-positive cells (p-value = 0.048) and by PARP-1 [0.55 vs. 1.02 arbitrary units (AUs), p-value = 0.001], BAX (1.91 vs. 1.05 AUs, p-value = 0.09), and BCL-2 (0.51 vs. 1.07 AUs, p-value = 0.0018) mRNA compared to control cells. The proliferation and wound-healing assays showed an anti-proliferative effect on DPG-IC₅₀-treated cells, also indicating an inhibitory effect on cell migration (p-values < 0.001). Moreover, it was observed that DPG promoted a 100% reduction in melanospheres formation (p-value = 0.008). Our previous microRNAs (miRs) global analysis has revealed that DPG might increase miR-4443 and miR-3620 expression levels. Thus, qPCR showed that after DPG treatment, SK-MEL-28 cells presented significantly high miR-4443 (1.77 vs. 1.04 AUs, p-value = 0.02) and miR-3620 (2.30 vs. 1.00 AUs, p-value = 0.01) expression compared to control cells, which are predicted to target the NF-kB, CD209 and TNC genes, respectively. Both genes are responsible for cell attachment and migration, and qPCR revealed significantly decreased CD209 (1.01 vs. 0.54 AUs, p-value = 0.018) and TNC (1.00 vs. 0.31 AUs, p-value = 2.38 × 10⁻⁶) mRNA expression levels after DPG compared to untreated cells. Furthermore, the migration of SK-MEL-28 cells stimulated by 12-O-tetradecanoylphorbol-13-acetate (TPA) was attenuated by adding DPG by wound-healing assay (48 h: p-value = 0.004; 72 h: p-value = 7.0 × 10⁻⁴). In addition, the MMP-9 expression level was inhibited by DPG in melanoma cells stimulated by TPA and compared to TPA-treated cells (3.56 vs. 0.99 AUs, p-value = 0.0016) after 24 h of treatment. Our results suggested that DPG has an apoptotic, anti-proliferative, and anti-migratory effect on SK-MEL-28 cells. DPG was also able to inhibit cancer stem-like cells that may cause cerebral tumor formation.     

和谐发展理念下建筑经济活动导则初探

对和谐发展理念下建筑经济价值综合体现的内容和特点进行了分析,结合自己建筑经济方面的实践工作经验,进而就和谐发展理念下建筑经济活动的指导性原则做了初步探讨.     

Patenting and licensing by Spanish firms: Available survey evidence

This paper presents the results of the OEPM (Spanish Patent and Trademark Office)/OECD (Organisation for Economic Co-operation and Development) survey on the economic and financial uses of patents carried out in 2008 among Spanish business applicants of OEPM patents. It also summarizes evidence from previous surveys. All available information indicates that only a few Spanish firms holding patents license them out. Results from the OEPM/OECD survey also reveal that obtaining public support is the first financial use of patents for Spanish firms. Responses to the same OECD questionnaire by EPO patent applicants from several European countries are quite different: licensing out is an extended practice among EPO patent holders from different countries, including Spain, and convincing venture capitalists and private investors are their two most important financial uses of patents. In our view this suggests that there are significant differences across European countries as regards the development of national technology markets and results from international surveys are driven by responses from the largest and more developed countries. The drivers and actors in markets for patents that only protect inventions nationally may be quite distinct from those in markets for patents that protect inventions regionally, such as EPO patents within Europe.     

基于相位法的炮口初速测量系统设计

针对某型小口径自动炮的炮口初速测量困难的问题,设计了一种基于相位法的炮口初速测量系统。介绍了测量系统的基本原理和测试流程,使用集成金属接近探测器 CS209A和模拟锁相环 NE564搭建硬件电路,由锁相环电路输出经 CS209A获取的弹丸通过炮口两确定距离上的感应线圈时产生的始末相位的相位差信号,并采用 LabVIEW编写的处理软件对采集的相位差信号进行分析计算,获得弹丸炮口初速。试验结果表明,该测量系统测试结果可靠,适合部队推广使用。     

分布式发电并网系统综述

随着分布式发电(Distributed Generation)应用的增加,越来越多的分布式发电正在接入电网,由此带来的并网问题日益重要:并网系统(包括硬件和软件)主要用来连接分布式发电和电网(通常是本地电网),本文主要讨论了分布式发电与电网之间的并网类型,并网系统的分类、功能、主要结构及采取的控制方法,并简要介绍了现有的分布式发电并网导则。     

Simulation of the VVER-1000 pump start-up experiment of the OECD V1000CT benchmark with CATHARE and TRAC-PF1

In the framework of joint effort between the Nuclear Energy Agency (NEA) of OECD, the United States Department of Energy (US DOE), and the Commissariat a l'Energie Atomique (CEA), France a coupled three-dimensional (3D) thermal-hydraulics/neutron kinetics benchmark for VVER-1000 was defined. The benchmark consists of calculation of a pump start-up experiment labelled V1000CT-1 (Phase 1), as well as a vessel mixing experiment and main steam line break (MSLB) transient labelled V1000CT-2 (Phase 2), respectively. The reference nuclear plant is Kozloduy-6 in Bulgaria. The overall objective is to assess computer codes used in the analysis of VVER-1000 reactivity transients. A specific objective is to assess the vessel mixing models used in system codes. Plant data are available for code validation consisting of one experiment of pump start-up (V1000CT-1) and one experiment of steam generator isolation (V1000CT-2). The validated codes can be used to calculate asymmetric MSLB transients involving similar mixing patterns. This paper summarizes a comparison of CATHARE and TRAC-PF1 system code results for V1000CT-1, Exercise 1, which is a full plant point kinetics simulation of a reactor coolant system (RCS) pump start-up experiment. The reference plant data include integral and sector average parameters. The comparison is made from the point of view of vessel mixing and full system simulation. CATHARE used a six-sector multiple 1D vessel thermal-hydraulic model with cross flows and TRAC used a six-sector, 18-channel coarse-mesh 3D vessel model. Good agreement in terms of integral parameters and inter-loop mixing is observed.     

规划·规范·规则:深圳开发控制三大体系的互动关系

规划、规范和规则是建设项目审批依据的三个基本来源,三者共同构成开发控制管理制度的三大核心体系。研究结合深圳实践,阐述三大体系的特征、构成和分类,分析三者在静态条件下的优先关系和在动态条件下的互动关系,尝试揭示三大体系之间相互替代、补充、促进、转化和融合的演化规律。     

Electricity intensity convergence in IEA/OECD countries: Aggregate and sectoral analysis

Convergence in electricity intensity is analyzed among a sample of IEA countries. Sigma-convergence (the narrowing of the distribution) and to a lesser degree gamma-convergence (movement within the distribution) are detected. However, electricity intensity convergence is less dramatic than energy intensity convergence. Convergence within the end-use sectors is more diverse: in terms of the rates, timing, extent, and ultimate modal structure of the distributions. Commercial electricity intensity has more recently converged toward a bell-shape distribution. By contrast, industry electricity intensity is largely converging toward two distinct groups of countries: one with relatively high electricity intensity and another one with relatively low electricity intensity. Different still is related residential electricity consumption per capita where a small group of countries has stopped growing; another group has slowed considerably, while a third group experienced rapid growth.