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1.
Diffusers are widely-used to quickly dilute effluents in receiving water bodies. This study proposed a novel diffuser that pre-mixes effluent with ambient water before discharging and that uses the swirling jet to further enhance near-field dilution. The nozzle of the diffuser was examined in two ambient flow conditions: co-flow and counter-flow that are commonly-met in the environment such as oceans due to tidal effect. Physical experiments were first conducted in co-flow on its dilution performance and hydrodynamics, using heated water as the effluent. A 3-D CFD model was developed and calibrated the co-flow scenarios, and then used to investigate the diffuser in counter-flow. The results showed that the nozzle can effectively reduce the maximum temperature rise of the effluent by about 50 % before discharging. The swirling jet from the outlet has a larger shear area, half-width and entrainment rate, enabling the effluent to be rapidly diluted to a minimum of around 10 times at x/D = 6 in co-flow, whereas the dilution for conventional nozzles is about 1 because of the potential core. The flow amplification ratio (α) decreases gradually with increasing velocity ratio in co-flow but increases with increasing velocity ratio in counter-flow. The counter-flow reduces the water drawn into the device; however, the pre-dilution effect at the outlet remains stable. The near-field dilution in counter-flow was significantly enhanced than that in co-flow. Environmental regulations at outfalls and mixing zones can be more easily met using this novel diffuser. 相似文献
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Mri Miczi Mria Golda Balzs Kunkli Tibor Nagy Jzsef Tzsr Jnos Andrs Mtyn 《International journal of molecular sciences》2020,21(24)
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease-19 (COVID-19) being associated with severe pneumonia. Like with other viruses, the interaction of SARS-CoV-2 with host cell proteins is necessary for successful replication, and cleavage of cellular targets by the viral protease also may contribute to the pathogenesis, but knowledge about the human proteins that are processed by the main protease (3CLpro) of SARS-CoV-2 is still limited. We tested the prediction potentials of two different in silico methods for the identification of SARS-CoV-2 3CLpro cleavage sites in human proteins. Short stretches of homologous host-pathogen protein sequences (SSHHPS) that are present in SARS-CoV-2 polyprotein and human proteins were identified using BLAST analysis, and the NetCorona 1.0 webserver was used to successfully predict cleavage sites, although this method was primarily developed for SARS-CoV. Human C-terminal-binding protein 1 (CTBP1) was found to be cleaved in vitro by SARS-CoV-2 3CLpro, the existence of the cleavage site was proved experimentally by using a His6-MBP-mEYFP recombinant substrate containing the predicted target sequence. Our results highlight both potentials and limitations of the tested algorithms. The identification of candidate host substrates of 3CLpro may help better develop an understanding of the molecular mechanisms behind the replication and pathogenesis of SARS-CoV-2. 相似文献
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分析了MOSFET误导通产生的原因,分别从原理和理论推导两个方面作了分析,主要考虑了开关管中寄生参数对开关特性的影响。通过求解误导通发生的条件,得到哪些参数会导致误触发,最后给出了仿真。文中还提出如何避免MOSFET误导通产生,以及改进方法,对减少实际应用中MOSFET破坏性损坏有一定意义。 相似文献
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CMOS光接收机主放大器设计 总被引:1,自引:0,他引:1
利用CMOS工艺设计一种用于SDH STM 4速率级(622 Mb/s)光纤用户网的光接收机放大电路。此电路由输入/输出缓冲、主放大单元、偏置补偿电路4部分组成。通过直接耦合技术提高增益,降低功耗;利用有源电感负载提高系统带宽。采用商用SmartSpice电路仿真软件和CSMC HJ 0.6μm工艺参数对该电路进行仿真。结果表明,该电路在5 V工作电压下中频增益为81 dB,3 dB带宽为470 MHz。 相似文献
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文中对万家寨引黄工程北干线1号隧洞Ⅳ标使用的155—274型TBM主轴承总成各部件组装过程及其相应的技术要求进行了概要的描述,目的是进一步熟悉155—274型TBM主轴承总成的各个部件并加深对主轴承工作原理的理解。 相似文献
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浅谈冲压模具的维修要领及常见故障的排除 总被引:1,自引:0,他引:1
介绍冲压模具修理和检查各环节的主要工作内容及维修要领 ,列举了常见故障的排除方法 ,通过总结实际生产中的修模经验 ,对缩短修模周期 ,降低成本 ,延长模具寿命有一定的参考价值。。 相似文献
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陆西凹陷包日温都断裂构造带岩性油藏研究 总被引:1,自引:1,他引:0
为寻找岩性油藏,应用波阻抗反演地震储层预测技术,对包日温都断裂构造带砂体展布情况进行了预测,发现并落实了2个岩性圈闭,由此认为,研究区北部是大型水下扇砂体与半深湖相暗色泥岩交汇之处,有利于形成岩性油藏,这一结论将对今后加强储层预测工作和寻找有利砂体提供借鉴。 相似文献