Rapid degradation of the mycotoxin patulin in man quantified by stable isotope dilution assays

The absorption and degradation of the mycotoxin patulin in man was quantified by using a recently developed stable isotope dilution assay. Application of this currently most sensitive method revealed a patulin content less than 200 ng l -1 in the blood serum of five consumers of apple juice. Likewise, no patulin was found in the serum of a volunteer, whose blood was drawn shortly after consumption of a juice containing a maximum tolerable amount of patulin. In further in vitro experiments, the degradation of patulin by reacting it with whole blood was investigated. After addition of 100 μg patulin to 9 ml blood, only 6.1% of the mycotoxin was detected after 2 min. It was concluded, therefore, that even high naturally occurring concentrations of patulin in foods are quickly degraded before reaching other tissues than the gastrointestinal tract.     

石油钻采阀门内壁热丝TIG堆焊

石油钻采专用阀门的使用有耐强腐蚀性要求，制造时需在内壁表层堆焊耐腐蚀材料。此类阀门具有质量大、形状特殊、焊接可达性差，焊接质量要求严格等特点；重点介绍了Fronius热丝TIG焊工艺和ETR全自动堆焊设备在阀门堆焊制造上的应用。     

重组人EC-SOD包涵体的稀释复性及重折叠后蛋白的纯化

目的确定重组人ECSOD包涵体体外稀释复性和复性后蛋白纯化的适宜方法。方法通过对pH、温度、包涵体蛋白浓度、尿素和精氨酸浓度及氧化还原对比率的定性定量分析,研究重组人ECSOD包涵体体外稀释复性的基本条件。采用金属离子亲和柱(IMAC)和肝素亲和柱(Heparinsepharose)对复性蛋白进行纯化,比较纯化效率的差异。结果最佳复性条件为pH8.5,尿素浓度为1.5molL,精氨酸浓度大于0.3molL,GSH∶GSSG=4∶1;复性温度及包涵体蛋白终浓度越高,复性效率越低。IMAC和Heparinsepharose亲和柱均可用来纯化复性蛋白溶液,但Heparinsepharose纯化效率较高。结论确定了重组人ECSOD包涵体体外稀释复性的最佳条件及复性后蛋白纯化的方法。     

Effects of neutral solvent addition on the body-centered cubic spheres of block copolymers

We employ self-consistent mean-field (SCMF) theory in studying the body-centered cubic (bcc) spheres of block copolymers in the presence of a neutral solvent. First we examine the accuracy of the dilution approximation then analyze the dependence of the bcc structural sizes with copolymer volume fraction ?, the interaction parameter χ_AB, and degree of copolymerization N. Our results reveal that both distribution of each component and the micro-structural length scales are greatly influenced by each parameter ?, χ_AB, and N. As expected, with decreasing ?, more solvent distributes non-uniformally in the segregated domains, therefore deviation from the dilution approximation increases. This also suggests that when the effective segregation parameter ?χ_ABN is fixed, a larger deviation is expected as χ_ABN increases (i.e. ? decreases). Although when both χ_ABN and ? are fixed, decreasing N (i.e. increasing χ_AB) enlarges the deviation from the dilution approximation. Furthermore, this solvent non-uniformity behavior is so significant that it even affects the dependence of the domain spacing L^* and the matrix length Λ^* with respect to (χ_AB)_effN=?χ_ABN near the ODT. When the systems are in molten state and/or in the concentrated regime, both L^* and Λ^* exhibit a sharp increase behavior as ODT is approached, due to many of the minority blocks being pulled from the spherical domains and swelling the matrix. With increasing solvent amount and/or χ_ABN, we observe that the increase of the degree for the minority blocks pulled from the spheres into the matrix near the ODT is not as significant as that in the melt. As such, the sharp increase behavior in L^* as well as Λ^* near the ODT smoothens and even disappears.     

沈阳含蜡油稀释三榨脱蜡新工艺

本文研制出一种新型的含蜡油稀释三榨脱蜡新工艺,该工艺对加工沈北减二线含蜡油十分有效,提高了石蜡质量与产量。     

Mineral admixtures in mortars: Effect of inert materials on short-term hydration

This work is the first part of an overall project the aim of which is the development of general mix design rules for concrete containing different kinds of mineral admixtures. The separation of the different physical effects responsible for the modification of cement hydration, when chemically inert quartz powders are used in mortars, is presented. The phenomenological approach, based on semi-adiabatic calorimetry, is only associated with first-order phenomena, and the study excludes the complex physicochemical details involved in the chemistry of cement. The results, obtained for a wide range of fineness (between 180 and 2000 m²/kg) and replacement rates (up to 75%), show that short-term degrees of hydration in mortars containing a chemically inert mineral admixture (quartz) are always higher than for a reference mortar. This study confirms that cement hydration is enhanced by inert mineral admixtures. The two main physical effects responsible for the modification of the hydration of cement are identified as the dilution effect and heterogeneous nucleation. The dilution effect of the cement is highlighted with a coarse mineral admixture. The heterogeneous nucleation effect, although it increases with fineness of mineral admixtures, presents an optimum depending on the replacement rate. In the following part of this work, these results will be used for the development of an empirical model allowing us to quantify both physical effects.     

Marine Wastewater Discharges from Multiport Diffusers. II: Unstratified Flowing Water

Laboratory experiments on the near-field mixing of buoyant plumes discharged from multiport diffusers into unstratified flowing water are reported. The spatial variation of dilution was measured by a newly developed three-dimensional laser-induced fluorescence system and a microconductivity probe. The near-field hydrodynamics are complex. The plumes discharged upstream dilute and merge more rapidly than those discharged downstream. Even with wide port spacing, the plumes eventually merge to form a laterally uniform surface wastefield. The density profile in this wastefield becomes gravitationally stable and suppresses mixing, marking the end of the near field. The value of the port spacing ratio, s/H, below which the discharge approximates a line plume is greater for discharge into a flowing current than into a stationary environment, so the port spacing plays a lesser role in a flowing current. The mixing and dilution that occurs in the surface layer is less than for a discharge into a stationary environment, and it decreases as the current speed increases. Semiempirical equations to predict the major near field characteristics are presented.     

卫星导航系统基四选星算法

随着卫星导航系统的发展,可见星数大大增多,为了减少接收机运算量,需选择可见卫星的一个子类。本文分析了卫星导航系统中N个4星最优分布与某4星最优分布中的k(k≤3)个卫星(共4N+k颗卫星)的联合分布GDOP值,并以此为基础提出了一类低复杂度近似最优的基四选星算法。该算法以经典的4星选择算法(最大体积法和四步选择法)为基础,通过多次迭代与部分执行,实现任意多于4星的卫星选择。仿真结果表明该算法与准优算法相比运算复杂度和GDOP值都更低。     

应用低贫化放矿的可行性浅析

鉴于鲁中冶金矿山公司现行截止品位放矿方式中存在贫化率较大的问题，提出采用提高截止品位的低贫化放矿方式，通过技术经济指标的分析计算，认为低贫化放矿技术上可行，经济上合理，在现场易于实现，具有应用价值。