人纤维蛋白原对急诊外伤致创伤性凝血病疗效及相关因素分析

目的:探讨人纤维蛋白原(fibrinogen，FIB)对急诊创伤性凝血病患者的临床疗效及相关因素。方法:将2015年6月至2018年6月本院收治的100例严重创伤患者纳入本研究，根据是否创伤性凝血病分为凝血病组(80例)和非凝血病组(20例)。比较凝血病组和非凝血病组患者收住后第1个24 h的急性生理和慢性健康评分(acute physiology and chronic health evaluation II，APACHE II)、创伤严重程度评分(injury severity score，ISS)、低体温及低灌注发生率等指标。采用Logistic多因素回归方法分析严重创伤患者发生创伤性凝血病的相关因素。将80例创伤性凝血病患者随机分为观察组(40例)和对照组(40例)。对照组按照常规诊疗措施治疗，观察组在对照组处理基础上给予人FIB，比较治疗前后观察组和对照组的凝血功能指标，及治疗后的临床用血量、住院时间及病死率。结果:与治疗前相比，治疗后观察组和对照组的凝血酶原时间(prothrombin time，PT)、活化部分凝血活酶时间(activated partial thromboplastin time，APTT)及D-二聚体水平降低(P<0.05)，FIB水平明显升高(P<0.05)。观察组的红细胞(red blood cell，RBC) 输注量、新鲜冰冻血浆(fresh frozen plasma，FFP)输注量、重症加强护理病房(intensive care unit，ICU)时间及病死率均明显低于对照组，差异具有统计学意义(P<0.05)。创伤性凝血病患者PT>18 s(r=0.623，P=0.024)、APTT>60 s(r=0.722，P=0.018)、凝血酶时间(thrombin time，TT)>15 s(r=0.719，P=0.033)与ISS评分呈正相关。碱缺失(base deficit，BD)≥6(OR=3.678，95%CI=1.065～9.417)、格拉斯哥评分(Glasgow coma scale，GCS)≤8(OR=5.299，95%CI=1.122～8.711)和血小板(platelet，PLT)计数(OR=0.982，95%CI=0.971～0.996)是严重创伤患者发生创伤性凝血病的独立预测因素。结论:人FIB可有效改善创伤性凝血病患者的凝血功能，降低病死率、缩短ICU时间，创伤性凝血病与创伤严重程度、合并休克、低体温和重型颅脑损伤存在一定的相关性。     

Makespan estimation and order acceptance in batch process industries when processing times are uncertain

Batch process industries are characterized by complex precedence relationships between operations, which renders the estimation of an acceptable workload very difficult. A detailed schedule based model can be used for this purpose, but for large problems this may require a prohibitive large amount of computation time. We propose a regression based model to estimate the makespan of a set of jobs. We extend earlier work based on deterministic processing times by considering Erlang-distributed processing times in our model. This regression-based model is used to support customer order acceptance. Three order acceptance policies are compared by means of simulation experiments: a scheduling policy, a workload policy and a regression policy. The results indicate that the performance of the regression policy can compete with the performance of the scheduling policy in situations with high variety in the job mix and high uncertainty in the processing times. Correspondence to: C.V. Ivanescu     

On basic definitions of unified fracture mechanics terminology

The adoption of unified fracture mechanics terminology (UFMT) will promote efficient communication between specialists in different fields of fracture research, harmonization of national and international standards relating to fracture mechanics, and last but not least improvement of the existing methodology for teaching and education in fatigue and fracture. In this paper the definitions of some basic and related terms included in different standards on fracture mechanics terminology are confronted with one another. Alternative definitions of the same terms are offered. By this strategy the author tries to show that the definitions of basic and related terms appropriate for the UFMT should emerge as a consequence of harmonizing a crack model with an actual crack and then both taken together with a fracture model, laboratory test methods, and failure assessment codes.Published in Problemy Prochonsti, No. 1, pp. 17–29, January, 1996.This paper is published as a matter of discussion.     

Superconductivity and magnetism in niobium doped YBa2Cu3O7 Related high Tc ceramics

Magnetic characterization has been performed on the members of the cuprateniobate RBa₂Cu₂NbO₈ (R = Pr, Nd, and La) series and R_1.5Ce_0.5Sr₂Cu₂NbO₁₀ (R = Pr, Eu, Nd, and Sm) series. The PrBCNO samples show a signature in the magnetization of a magnetic ordering at 12K. The PrCSCNO sample is nonsuperconducting and shows two distinct orderings at 17K and 53K. No such magnetic phase transition is observed down to 2K in the Nd and La based RBCNO materials or the Nd, Sm, and Eu based RCSCNO materials. Measurements of the lower critical field curve, dc irreversibility line, and critical curent densities are reported for each of the superconducting NdCSCNO, SmCSCNO, and EuCSCNO compounds.     

Appraisal as a Pervasive Determinant of Anger.

L. Berkowitz and E. Harmon-Jones (see record 2004-15096-001) challenge appraisal theories of emotion by describing 2 sets of conditions (physical discomfort and anger-related muscle actions) in which anger appears to be elicited in the absence of theoretically predicted appraisals. In response, the authors discuss the ability of the specific appraisal model they have developed (e.g., C. A. Smith & L. D. Kirby, 2000, 2001; C. A. Smith & R. S. Lazarus, 1990) to account for such instances of anger. First, a number of issues are clarified relevant to the authors' model, including the nature of both the cognitive operations underlying appraisal and the specific appraisals hypothesized to evoke anger. The authors then describe how their model can account for the instances of anger described by L. Berkowitz and E. Harmon-Jones and how both accounts might be tested. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Toward an Understanding of the Determinants of Anger.

Research bearing on several popular conceptions of the major determinants of anger arousal indicates that the particular appraisals often identified as causes of anger frequently only serve to affect the intensity of the anger that is generated. Research into effects of physical pain or other physically unpleasant conditions or involving social stresses suggests that decidedly aversive conditions are a major spur to anger. Experiments are also reviewed showing that anger-related muscular movements can also lead to anger-related feelings, memories, cognitions, and autonomic responses. Alternative explanations for the findings are discussed. The authors urge emotion theorists to widen their methodology and analyses so that they give careful, detailed attention to the many different factors that can influence anger. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

舰船用断路器抗冲击欠压脱扣器的设计

对断路器的欠压脱扣器结构进行分析和研究 ,采用平衡机构、弹性球效应等抗冲击设计方法 ,并通过理论计算和验证 ,将H—DW14舰船用断路器的欠压脱扣器设计成具有抗冲击能力的产品 ,以适应舰船的要求。     

Energy and resources as production factors in process industries

It is shown that, when the mean productivity of some factors, such as energy or materials, is upperly bounded (a condition usually arising in energy production or in the process industries where energy takes part in physico-chemical processes), the production function may not be convex and, under some further conditions, is concave. Consequences of this model on the economics of energy savings are examined, and it is shown that energy savings may be considered at three levels: in the short run, by action on labour factors: in the medium run, by investment and action on labour factors; in the long run, by technological innovation, investment in new technologies and action on labour factors. Empirical findings along these lines are thus confirmed.     

Anaerobic digestion of alkaline black liquor using an up-flow anaerobic sludge blanket reactor

The anaerobic digestion of alkaline black liquor from a cereal straw pulping mill was studied in batch (serum bottles) and continuous systems (up-flow anaerobic sludge blanket reactor—UASB). The batch digestion studies confirmed that lignin and related compounds (LRC) in the alkaline black liquor were the main inhibitory substances and could not be decomposed by anaerobic bacteria. At organic loading rates of 5–10 kg COD m^?3 day^?1, the UASB reactor achieved 50–60% COD removal efficiencies. Gas production was 2–3 dm³ per dm³ of alkaline black liquor. Two different sludge types were examined in the reactor: granular and cluster-like sludges. Sludge in a cluster, which involved many small granules and flocs, tended to form larger aggregates and possessed good settling ability.     

融合创意产业的民族手工艺品发展策略

文章首先介绍湖南、贵州等地少数民族手工艺产品的当代状况,并从传统工艺的文化的传承和资本的流动的角度进行了分析。之后,文章简介了台湾省内对于创意产业的发展的部分经验,总结融合创意产业发展少数民族手工艺产品的发展策略。