Xilinx XC4000系列FPGA自动测试平台搭建

随着FPGA的发展,FPGA测试技术也得到了相应的发展。因为FPGA的结构和传统专用集成电路(ASIC)有着本质的区别,在FPGA中不能形成可测性设计电路,但它的可编程能力决定了其测试电路可以通过编程的方法来实现。本文讨论了Xilinx XC4000系列FPGA中CLB资源和互连资源的自动测试方法。而且提出了一种新的测试资源坐标定位方法,使得由软件仿真向器件真实测试取得了突破。并搭建了硬件测试平台。     

基于Modbus RTU协议的水箱液位监控系统设计与实现

介绍了利用VB6.0实现工控机和研华ADAM4000模块Modbus通信的设计方法,并将此方法应用于水箱液位监控系统设计中。测试结果表明,此系统能实现水箱液位的恒定控制,对水箱液位、调节阀开度和流量可以实现在线监测。     

三元体系PEG 4000-Cs2SO4-H2O在25,35和45 ℃时的相平衡研究

采用自制的相平衡研究装置，测定了PEG 4000-Cs2SO4-H2O三元体系在25，35和45℃时的等温平衡溶解度，同时给出了该体系的完整相图，在相图中观察到6个相区。结果表明，该体系双液相区随着温度的升高略有增加，结线的斜率也随温度的升高而增大。用四参数方程y=a bx^0.5 cχ dχ^2对该体系的双液线进行了拟合，拟合结果较好。用Othmer-Tobias方程和Bancroft方程对该体系结线的实验数据进行了关联，所有线性相关系数均大于0．98。热重分析确定平衡固相组成为无水硫酸铯。     

PEG4000用量对溶胶-凝胶法制备多孔钛酸锶光催化剂的影响

以聚乙二醇PEG4000为模板剂,采用溶胶-凝胶法制备多孔钛酸锶光催化剂,研究PEG4000添加量对催化剂组成和性能的影响。结果表明:添加模板剂后样品的比表面积显著增大,钛酸锶的物相由Sr2TiO4转变成SrTiO3。随着模板剂添加量的增加,样品的颗粒粒径逐渐变小,SrTiO3相的晶粒尺寸也逐渐下降。当PEG4000的添加量为1.5g时,多孔样品由SrTiO3和SrCO3相组成,SrTiO3相的特征衍射峰强度最大,样品的光催化活性最强。当光催化时间为120min时,甲基橙在多孔样品上的降解率为97.9%,明显高于未添加PEG4000制备的样品。     

Lonidamine Solid Dispersions: In Vitro and In Vivo Evaluation

ABSTRACT

Solid dispersions of lonidamine in PEG 4000 and PVP K 29/32 were prepared by the spray-drying method. Then, the binary systems were studied and characterized using differential scanning calorimetry, hot stage microscopy, and x-ray diffractometry. In vitro dissolution studies of the solid dispersed powders were performed to verify if any lonidamine dissolution rate or water solubility improvement occurred. In vivo tests were carried out on the solid dispersions and on the cyclodextrin inclusion complexes to verify if this lonidamine water solubility increase was really able to improve the in vivo drug plasma levels. Drug water solubility was increased by the solid dispersion formation, and the extent of increase depended on the polymer content of the powder. The greater increase of solubility corresponded to the highest content of polymer. Both the solid dispersions and the cyclodextrin complexes were able to improve the in vivo bioavailability of the lonidamine when administered per os. Particularly, the AUC of the drug plasma levels was increased from 1.5 to 1.9-fold depending on the type of carrier.     

ADAM-4000在QCS生料质量控制系统中的应用

概述了QCS水泥生料质量控制系统的要求及ADAM-4000的特性。介绍了ADAM-4000在QCS生料质量控制系统中的应用及使用注意事项。     

Lonidamine solid dispersions: in vitro and in vivo evaluation

Solid dispersions of lonidamine in PEG 4000 and PVP K 29/32 were prepared by the spray-drying method. Then, the binary systems were studied and characterized using differential scanning calorimetry, hot stage microscopy, and x-ray diffractometry. In vitro dissolution studies of the solid dispersed powders were performed to verify if any lonidamine dissolution rate or water solubility improvement occurred. In vivo tests were carried out on the solid dispersions and on the cyclodextrin inclusion complexes to verify if this lonidamine water solubility increase was really able to improve the in vivo drug plasma levels. Drug water solubility was increased by the solid dispersion formation, and the extent of increase depended on the polymer content of the powder. The greater increase of solubility corresponded to the highest content of polymer. Both the solid dispersions and the cyclodextrin complexes were able to improve the in vivo bioavailability of the lonidamine when administered per os. Particularly, the AUC of the drug plasma levels was increased from 1.5 to 1.9-fold depending on the type of carrier.     

国内首条4000t钢管水压试验机机组的研制

介绍了太原重工技术中心研制的的国内首条4000t水压试验机组的机构特点和性能参数。该水压试验机是目前国内试验压力最大的,并首次采用了倾斜机架布置方式及滚动支撑结构的新型设备。     

Preparation of a Solid Dispersion by a Dropping Methodto Improve the Rate of Dissolution of Meloxicam

Application of a solid dispersion system is one of the methods used to increase the bioavailability of poorly water-soluble drugs. Adaptation of the dropping method from the chemical industry as a formulation procedure may help the scaling-up process and simplify the formulation of poorly water-soluble compounds. Meloxicam (ME), a nonsteroidal anti-inflammatory drug that is poorly soluble in water, and polyethylene glycol (PEG) 4000, a water-soluble carrier, were formulated by using a dropping method in an attempt to improve the dissolution of ME. Pure ME and physical mixtures and tablets of ME–PEG 4000 (1:3 ratio) were compared as regards their dissolution with samples formulated by the dropping method. The results revealed that the round particles (solid drops) exhibited a higher dissolution rate than those of the physical mixtures, tablets, and pure ME. Self-modeling curve resolution (SMCR) as a chemometric method was used to evaluate X-ray powder diffractometry (XRPD) data. The results demonstrated the presence of a new crystalline phase in the solid dispersion, which can help the fast and quantitative dissolution from the solid drops. The round particles can be adapted to individual therapy by using a distributor.     

基于LTC4000 的锂电池充电模块

为了达到高效、便捷、低成本的充电目的,设计一款基于LTC4000的锂电池充电模块。该模块以三阶段充电法为设计理念,硬件方面选用 MSP430系列单片机作为主控芯片,具有电压、电流调节模块实现稳定输出,软件方面通过MODBUS协议和RS485物理接口实现与上位机的通信,并制作PCB电路板对该模块进行验证。实验结果证明：该系统结构简单、携带方便、实用性强,上电后能迅速达到稳定状态,有广阔的市场前景。